research 588 Skin fibroblast heterogeneity and plasticity are determined by the local niche
Mouse skin fibroblasts vary in function and adaptability based on their environment.
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840-870 / 1000+ results research Human keratin hydrogels support fibroblast attachment and proliferation in vitro
research Fibroblast state switching orchestrates dermal maturation and wound healing
Fibroblast state switching is crucial for skin healing and development.
research Deep skin fibroblast-mediated macrophage recruitment supports acute wound healing
Deep skin fibroblasts help recruit immune cells for better wound healing.
research SFRP2/DPP4 and FMO1/LSP1 Define Major Fibroblast Populations in Human Skin
Two main types of fibroblasts with unique functions and additional subtypes were identified in human skin.
research Fibroblasts in Diabetic Foot Ulcers
Understanding fibroblast issues in diabetic foot ulcers is key to creating better treatments.
research Rare Gli1+ perivascular fibroblasts promote skin wound repair
Rare Gli1+ fibroblasts are crucial for skin wound healing.
research Regeneration of Dermis: Scarring and Cells Involved
Different fibroblasts play key roles in skin healing and scarring.
research Fibroblast Lineage Switching as the Developmental Origin of Scarring and Target for Regenerating Healing
Mimicking fetal wound environments may enable scarless healing in adults.
research Fibroblast depletion reveals mammalian epithelial resilience across neonatal and adult stages
The skin can still regenerate and function well even with fewer fibroblasts.
research Microporous Dermal-Mimetic Electrospun Scaffolds Pre-Seeded with Fibroblasts Promote Tissue Regeneration in Full-Thickness Skin Wounds
Pre-seeding scaffolds with fibroblasts improves skin wound healing.
research Hair-follicle dermal papilla and sheath fibroblasts provide a supportive microenvironment for human skin regeneration
Certain cells around hair follicles help improve skin regeneration for potential use in skin grafts.
research Epithelial Fibronectin meshwork controls skin regeneration
Fibronectin is essential for hair follicle regeneration by supporting stem cells.
research Dynamic ultrastructural changes of the connective tissue sheath of human hair follicles during hair cycle
The connective tissue around hair follicles changes structure throughout the hair cycle.
research Fibroblasts and endothelial cells interplay drives hypertrophic scar formation: Insights from in vitro and in vivo models
Fibroblast and endothelial cell interactions are crucial in forming hypertrophic scars.
research From Design to Production: Applications of Polymer and Protein Nanofibers for Regenerating Tissue
FN nanofiber dressings improve wound healing and restore natural skin structure.
research Outer root sheath (ORS) cells organize into epidermoid cyst-like spheroids when cultured inside Matrigel: a light-microscopic and immunohistological comparison between human ORS cells and interfollicular keratinocytes
research Human Dermal Fibroblasts Demonstrate Positive Immunostaining for Neuron- and Glia- Specific Proteins
Fibroblasts can be mistaken for neural cells, so functional validation is needed.
research Fibroblast Growth Factors in Epithelial Homeostasis and Repair
Fibroblast Growth Factors (FGFs) help maintain and repair skin tissues, which is important for preventing diseases like inflammation, fibrosis, and cancer.
research Fibroblast Lineage Switching as the Developmental Origin of Scarring and Target for Regenerative Healing
Reprogramming adult fibroblasts may enable scar-free healing.
research Single‐cell transcriptomic analysis of small and large wounds reveals the distinct spatial organization of regenerative fibroblasts
Different types of skin cells are organized in a special way in large wounds to help with healing and hair growth.
research 866 Senescent fibroblasts secretome promote tumoural initiation of normal human keratinocytes through cellular activation, enhanced migration and ECM remodelling
Senescent fibroblasts can help start tumors in normal skin cells.
research Wound-healing effects of frozen-thawed allogeneic fibroblast sheet transplantation and xenogeneic fibroblast cell sheet transplantation cultured on a new substrate
Frozen-thawed fibroblast sheets enhance wound healing and hair growth in mice.
research Nucleation and growth of macrofibrils in trichocyte (hard-α) keratins
Sheet formation is key to macrofibril structure differences in wool.
research Multi-omics analysis unveils the role of cancer-associated fibroblasts in cutaneous squamous cell carcinoma
Cancer-associated fibroblasts promote tumor growth in skin cancer.
research Fibroblast growth factors: key players in regeneration and tissue repair
Fibroblast Growth Factors (FGFs) are important for tissue repair and regeneration, influencing cell behavior and other factors involved in healing, and are crucial in processes like wound healing, bone repair, and hair growth.
research 259 Scalp hair follicle dermal sheath fibroblasts express genes associated with promotion of skin integrity/wound healing and prevention of autoimmune responses in Recessive Dystrophic Epidermolysis Bullosa
Scalp hair follicle cells help protect and heal skin in certain skin conditions.
research Cultured human skin fibroblasts: a model for the study of androgen action
research Single-cell analysis reveals fibroblast heterogeneity and myeloid-derived adipocyte progenitors in murine skin wounds
The research found that different types of fibroblasts are involved in wound healing and that some blood cells can turn into fat cells during this process.
research Heparin-based sericin hydrogel–encapsulated basic fibroblast growth factor for in vitro and in vivo skin repair
The hydrogel significantly speeds up wound healing and supports skin cell growth.