research Dissecting the bulge in hair regeneration
Stem cells in hair follicles are diverse and change throughout the hair cycle.
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research Human αβ and γδ T Cells in Skin Immunity and Disease
Certain types of T cells are essential for healthy skin and play a role in skin diseases, but more research is needed to improve treatments.
research Vitamin D-dependent rickets type II. Defective induction of 25-hydroxyvitamin D3-24-hydroxylase by 1,25-dihydroxyvitamin D3 in cultured skin fibroblasts.
Measuring 24-OHase induction helps identify defects in vitamin D processing and predict treatment response.
research Ornithine decarboxylase is a target for chemoprevention of basal and squamous cell carcinomas in Ptch1+/– mice
Inhibiting ornithine decarboxylase may help prevent certain skin cancers.
research Ornithine decarboxylase is a target for chemoprevention of basal and squamous cell carcinomas in Ptch1+/– mice
Targeting ornithine decarboxylase can help prevent skin cancer.
research Involvement of 4‐hydroxy‐2‐nonenal in pollution‐induced skin damage
Pollution increases a compound in the skin that can lead to faster aging and more inflammation.
research High resolution full scan liquid chromatography mass spectrometry comprehensive screening in sports antidoping urine analysis
The method effectively detects banned substances in urine for sports antidoping.
research Gender aspects in skin diseases
Men are more likely to get infectious skin diseases, while women are more prone to autoimmune and pigment-related skin conditions, influenced by biological and environmental factors.
research High-throughput T cell receptor sequencing identifies clonally expanded CD8+ T cell populations in alopecia areata
CD8+ T cells are involved in alopecia areata and may cause disease relapse.
research SYK inhibitor entospletinib prevents ocular and skin GVHD in mice
Entospletinib effectively prevents eye and skin GVHD in mice.
research Selective inhibition of JAK3 signaling is sufficient to reverse alopecia areata
Blocking JAK3 signaling can reverse hair loss from alopecia areata.
research Radiation-Induced Microvascular Injury as a Mechanism of Salivary Gland Hypofunction and Potential Target for Radioprotectors
Radiation damages salivary glands by harming blood vessels, but antioxidants might help protect them.
research Metabolic Syndrome and Skin Diseases
Metabolic Syndrome is linked to several skin conditions, and stem cell therapy might help treat them.
research Effects of Hair Follicle Stem Cells on Partial-Thickness Burn Wound Healing and Tensile Strength
Hair follicle stem cells help burns heal faster and stronger.
research Isolation of epithelial stem cells from dermis by a three-dimensional culture system
Researchers isolated a new type of stem cell from mouse skin that can renew itself and turn into multiple cell types.
research Skin inflammation activates intestinal stromal fibroblasts and promotes colitis
Skin inflammation can worsen intestinal inflammation and colitis.
research Neural Wiskott-Aldrich syndrome protein modulates Wnt signaling and is required for hair follicle cycling in mice
N-WASP is essential for normal hair growth in mice.
research Vasoactive intestinal peptide, whose receptor-mediated signalling may be defective in alopecia areata, provides protection from hair follicle immune privilege collapse
A substance called VIP might protect hair follicles from being attacked by the immune system, and problems with VIP signaling could lead to hair loss in alopecia areata.
research Evaluation of the predictive capacity of DNA variants associated with straight hair in Europeans
Certain DNA variants can predict straight hair in Europeans but are not highly specific.
research In vitro Antibacterial Activity of Alkaloids Isolated from Leaves of Eclipta alba Against Human Pathogenic Bacteria
Eclipta alba leaves have compounds that can fight certain harmful bacteria.
research Hair follicle stem cell replication stress drives IFI16/STING-dependent inflammation in hidradenitis suppurativa
Stress in hair follicle stem cells causes inflammation in a chronic skin condition through a specific immune response pathway.
research IL-36γ drives skin toxicity induced by EGFR/MEK inhibition and commensal Cutibacterium acnes
A protein called IL-36γ causes skin side effects from certain cancer treatments when combined with a common skin bacteria.
research Fatty acids and related lipid mediators in the regulation of cutaneous inflammation
Certain fats in the skin help control inflammation and health, and changing these fats through diet or supplements might treat skin inflammation.
research Geriatric challenges in the new coronavirus disease-19 (COVID-19) pandemic: A systematic review
Elderly people, especially with chronic conditions, are more at risk of severe COVID-19 complications and need preventive care and social support.
research A transcriptomic map of murine and human alopecia areata
Alopecia areata involves specific immune cells, offering potential treatment targets.
research Hormonal activity in commonly used Black hair care products: evaluating hormone disruption as a plausible contribution to health disparities
Common Black hair care products may affect hormone levels and potentially impact health, especially in reproductive and metabolic areas.
research Iontophoresis of minoxidil sulphate loaded microparticles, a strategy for follicular drug targeting?
Iontophoresis improves minoxidil delivery to hair follicles for hair loss treatment.
research Helicobacter pylori infection and skin disorders
Some skin disorders might be linked to H. pylori infection, but more research is needed to confirm this.
research Phytochemical investigation and hair growth studies on the rhizomes of Nardostachys jatamansi DC
Nardostachys jatamansi DC compounds help promote hair growth.
research Development of a nude mouse model to study human sebaceous gland physiology and pathophysiology.
The model using human skin on mice helps study human sebaceous glands.