8 citations
,
October 2019 in “The Journal of surgical research/Journal of surgical research” Sodium valproate helps skin healing by affecting GABA and histone deacetylase.
6 citations
,
September 2012 in “Aesthetic Plastic Surgery” Minoxidil applied before and after surgery improves skin flap survival in rats.
1 citations
,
January 2019 in “Advances in Medical Sciences” The combination of azelaic acid, minoxidil, and caffeine significantly increased the survival of skin flaps by affecting certain body channels and nitric oxide levels.
12 citations
,
August 2015 in “Plastic Surgery” Botulinum toxin may help reduce skin flap damage caused by cigarette smoke.
25 citations
,
January 2001 in “Facial Plastic Surgery” Both tissue expansion and serial excision are effective for scar revision in the head and neck area.
5 citations
,
January 1985 in “Facial Plastic Surgery” Flap surgery is effective for treating male baldness, offering immediate results with dense hair growth.
January 2006 in “Chinese Journal of Aesthetic Medicine” Zinc improves skin flap survival in rats.
4 citations
,
June 2013 in “Aesthetic Plastic Surgery” Minoxidil improved rat skin flap survival but was less effective than surgical methods.
50 citations
,
May 1999 in “Journal of Reconstructive Microsurgery” Microsurgical reconstruction effectively covers complex scalp defects but doesn't improve survival for cancer-related cases.
December 1994 in “The American Journal of Cosmetic Surgery” Understanding the scalp's blood flow and using delay techniques can improve the success of hair restoration surgeries.
November 2002 in “Dermatologic Surgery” Scalp reduction gives the most natural result for significant crown baldness, despite potential complications, and a systematic approach to surgical hair restoration results in few complications and high graft survival.
1 citations
,
January 2025 in “Head & Neck” The snail flap technique is an easy, reliable, and hair-preserving method for scalp reconstruction, especially good for elderly or frail patients.
1 citations
,
February 2015 in “PubMed” 5α-reductase inhibitors may help skin flaps survive better by affecting nitric oxide.
19 citations
,
February 2008 in “Facial Plastic Surgery” The article concludes that microvascular free flaps, especially the latissimus dorsi flap, are recommended for large scalp reconstructions, and hair transplantation offers high survival rates and excellent aesthetic results.
June 2024 in “Archives of Plastic Surgery” Hair transplantation on a reconstructed scalp can effectively improve hair growth and appearance.
4 citations
,
May 2013 in “Annals of Plastic Surgery” Hair transplants onto a scalp reconstruction flap improved appearance successfully.
March 2025 in “Wound Repair and Regeneration” The hydrogel scaffold improved skin flap healing and reduced inflammation.
15 citations
,
May 2015 in “Photomedicine and Laser Surgery” Low-Level Laser Therapy may help with flap survival and burn scar healing, but not with venous ulcers or hair loss, and more research is needed.
2 citations
,
January 2013 in “Hair therapy & transplantation” Hair transplants can be a treatment for scarring hair loss if there's good blood flow and no active disease.
18 citations
,
May 2017 in “Head & Neck” Free tissue transfer is highly effective for fixing exposed implants after skull surgery.
1 citations
,
January 2010 in “Elsevier eBooks” The document concludes that local flaps are effective for reconstructive surgery in the head and neck, offering good skin match and function.
June 2017 in “Experimental dermatology” Skin has a larger surface area than thought, certain skin cells improve skin flap survival, better trials for skin conditions in children are needed, Stevens-Johnson syndrome rates vary by age and race, and better skin barrier function may reduce inflammation in the elderly.
March 2026 in “Panacea Journal of Medical Sciences” The technique successfully reconstructed a functional neo-vagina with 100% survival and patency, but lacked mucus secretion.
Various substances, quitting smoking, and certain topical applications can enhance the survival of skin flaps used in surgery. Oxygen-free radicals play a role in tissue injury, but certain treatments can have beneficial effects.
September 2021 in “Journal of the European Academy of Dermatology and Venereology” Francisco Camacho Martinez has made significant contributions to skin and sexually transmitted diseases, developed surgical techniques, but is concerned about patient survival rates and over-specialization in dermatology.
14 citations
,
September 2001 in “Dermatologic Surgery” The document concludes that following specific surgical guidelines can improve scalp surgery results and reduce complications.
Combining microneedling with platelet-rich plasma enhances skin repair and collagen production but may not offer significant extra benefits.
January 2020 in “Medical Journal of Clinical Trials & Case Studies” Topical minoxidil effectively prevents tissue death in certain surgeries.
September 2007 in “Dermatologic Surgery” 3% hydrogen peroxide does not reduce hair graft survival compared to saline.
8 citations
,
March 2009 in “Aesthetic Plastic Surgery” The "flying-wings" scalp flap technique is a simple, safe, and effective way to reconstruct large areas of scalp loss in children.