research Nano-PROTACs: state of the art and perspectives
Nano-PROTACs could improve drug targeting and delivery by using nanotechnology.
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research Steroidal 5α-reductase and 17α-hydroxylase/17,20-lyase (CYP17) inhibitors useful in the treatment of prostatic diseases
Certain drugs that block specific enzymes can help treat prostate diseases.
research A novel finasteride 0.25% topical solution for androgenetic alopecia: pharmacokinetics and effects on plasma androgen levels in healthy male volunteers
New finasteride solution effectively reduces baldness-causing hormone, potentially with fewer side effects.
research What controls hair follicle cycling?
The control system for hair growth cycles is not well understood and needs more research.
research Design of a biofluid-absorbing bioactive sandwich-structured Zn–Si bioceramic composite wound dressing for hair follicle regeneration and skin burn wound healing
Wound dressing absorbs fluid, regenerates hair follicles, and heals skin burns.
research Novel skin patch combining human fibroblast-derived matrix and ciprofloxacin for infected wound healing
The new skin patch with human matrix and antibiotic improves wound healing.
research Activation of Wnt Signaling in Hematopoietic Regeneration
Wnt10b helps blood stem cells grow after injury.
research Microneedle-Based Approaches for Skin Disease Treatment
Microneedles offer a promising, painless way to treat skin diseases but need improvements for better use.
research Noncoding dsRNA induces retinoic acid synthesis to stimulate hair follicle regeneration via TLR3
Noncoding dsRNA boosts hair growth by activating TLR3 and increasing retinoic acid.
research A nude mouse model of hypertrophic scar shows morphologic and histologic characteristics of human hypertrophic scar
Nude mice with grafted human skin developed scars similar to human hypertrophic scars.
research Recent studies on the delivery of hydrophilic drugs in nanoparticulate systems
Nanoparticulate systems improve drug delivery by controlling release, protecting drugs, changing absorption and distribution, and concentrating drugs in targeted areas.
research Chrousos syndrome: from molecular pathogenesis to therapeutic management
The review suggests thorough evaluation and genetic testing for proper diagnosis and treatment of Chrousos syndrome.
research Sustained release of dermal papilla-derived extracellular vesicles from injectable microgel promotes hair growth
Injecting a special gel with human protein particles can help hair grow.
research Adaptations in the structure and innervation of follicle‐sinus complexes to an aquatic environment as seen in the Florida manatee (Trichechus manatus latirostris)
Manatee whiskers are specially adapted for touch in water.
research Thyrotropin-Releasing Hormone (TRH) Promotes Wound Re-Epithelialisation in Frog and Human Skin
Thyrotropin-Releasing Hormone helps heal wounds in frog and human skin.
research Natural Bizbenzoquinoline Derivatives Protect Zebrafish Lateral Line Sensory Hair Cells from Aminoglycoside Toxicity
Some natural compounds can protect fish ear cells from damage by certain antibiotics without affecting the antibiotics' ability to fight infections.
research Acquired scalp alopecia. Part I: A review
Accurate diagnosis is key for treating different kinds of hair loss, and immune response variations may affect the condition and treatment results.
research Lymphatic vessels interact dynamically with the hair follicle stem cell niche during skin regeneration in vivo
Lymphatic vessels are essential for hair follicle growth and skin regeneration.
research Primary cicatricial alopecia: Recent advances in understanding and management
New understanding of the causes of primary cicatricial alopecia has led to better diagnosis and potential new treatments.
research Hoxc-Dependent Mesenchymal Niche Heterogeneity Drives Regional Hair Follicle Regeneration
Hoxc genes control hair growth through Wnt signaling.
research Fat, Stem Cells, and Platelet-Rich Plasma
The conclusion is that fat grafting is safe and effective but carries risks that need careful management.
research Mechanical Stretch Upregulates SDF-1α in Skin Tissue and Induces Migration of Circulating Bone Marrow-Derived Stem Cells into the Expanded Skin
Stretching skin increases a certain protein that attracts stem cells, helping skin regeneration.
research Hair cosmetics
The article concludes that advancements in hair cosmetics require dermatologists to stay informed about products and their potential risks, including allergies and higher risks for hairdressers.
research Microneedle Arrays Combined with Nanomedicine Approaches for Transdermal Delivery of Therapeutics
Microneedle arrays with nanotechnology show promise for painless drug delivery through the skin but need more research on safety and effectiveness.
research Analysis of Protein Interactions by Surface Plasmon Resonance
Surface Plasmon Resonance is a useful tool for studying protein interactions and has potential for future technological advancements.
research Azathioprine
Azathioprine's effectiveness and safety require careful monitoring and more research, especially regarding its use with corticosteroids and the role of TPMT status in patients.
research Repurposing of Drugs as Novel Influenza Inhibitors From Clinical Gene Expression Infection Signatures
A blood pressure drug, diltiazem, may also help treat influenza.
research The Role of Adipocytes in Tissue Regeneration and Stem Cell Niches
Fat cells are important for tissue repair and stem cell support in various body parts.
research Steroid 5α-Reductase Inhibitors
New steroidal compounds could be effective for treating conditions related to 5α-reductase enzyme activity.
research Targeted delivery of extracellular vesicles: the mechanisms, techniques and therapeutic applications
Engineered extracellular vesicles show promise for targeted therapy but need more research for clinical use.