5 citations
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January 2007 in “Annals of Internal Medicine” Folic acid might help with age-related hearing loss.
January 2014 in “Dermatology Review” Folate may reduce methotrexate side effects in psoriasis patients, but its impact on effectiveness is unclear.
1 citations
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October 2023 in “JEADV. Journal of the European Academy of Dermatology and Venereology/Journal of the European Academy of Dermatology and Venereology” A man developed skin lesions as a side effect of a gamma secretase inhibitor used for treating a tumor.
July 2024 in “Brazilian Journal of Clinical Medicine and Review” Hair loss after bariatric surgery is common due to nutrient deficiencies and rapid weight loss.
November 2015 in “Ankara Medical Journal” Weekly 5 mg folate is enough to prevent methotrexate toxicity in rheumatoid arthritis patients.
October 2019 in “Turkderm” Patients with pernio have lower vitamin B12 and ferritin levels than healthy people.
December 2021 in “Vestnik Rossiĭskoĭ akademii meditsinskikh nauk / Rossiĭskaia akademiia meditsinskikh nauk” Personalized vitamin and trace element treatment improves hair density and reduces hair loss in men with early-stage androgenic alopecia.
January 2023 in “National journal of physiology, pharmacy and pharmacology” Low-dose methotrexate is generally safe but can cause mild to severe side effects, and folic acid can reduce these risks.
63 citations
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May 2017 in “American Journal of Clinical Dermatology” People with alopecia areata often have lower levels of vitamin D, zinc, and folate, but more research is needed to understand if supplements can help treat it.
Older people tend to have higher biotin levels, which are weakly linked to certain blood components and negatively linked to triglycerides; biotin should be checked in patients with high triglycerides or medication-related skin issues, and only supplemented if deficient. Vitamin D and folate deficiencies are linked to specific skin conditions.
May 2022 in “Zenodo (CERN European Organization for Nuclear Research)” Weight loss improved health issues, but calcium and protein intake need attention.
The 1298CC genotype in RA patients leads to higher methotrexate toxicity, while the 1298AA genotype results in better treatment response.
20 citations
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July 1990 in “Clinical and experimental dermatology” Taking cyproterone acetate and ethinyl oestradiol for hair loss can lower vitamin B12 levels in women.
June 2017 in “Journal of clinical and investigative dermatology” Red blood cell folate levels are reliable indicators of long-term folate status in alopecia areata patients.
3 citations
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November 2020 in “Curēus” A child's hair loss from alopecia areata was fully reversed in five months using diet and supplements.
Folate salts penetrate skin well and improve wound healing, suggesting potential for skin treatments.
January 2018 in “International journal of medical biochemistry” Women with telogen effluvium have lower levels of iron, folate, and vitamin B12.
September 2009 in “European journal of paediatric neurology” Biotin supplements did not significantly reduce hair loss in rats on valproic acid.
3 citations
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November 2018 in “PubMed” People with TED often have low B12 levels and might benefit from B12 supplements.
2 citations
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April 2019 in “Медицинский совет” Combined oral contraceptives improve skin, hormone levels, and quality of life in women with PCOS.
1 citations
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September 2025 in “Frontiers in Immunology” Folate receptor β helps suppress the immune system in macrophages and affects cancer growth and hair health.
June 2024 in “Research Square (Research Square)” Young women in West Bengal, India, with PCOS often have estrogen resistance, leptin receptor issues, folate deficiency, T2DM, and acanthosis, commonly linked to obesity.
239 citations
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July 2002 in “Clinical and Experimental Dermatology” Low iron and L-lysine levels can cause hair loss in women, and increasing these nutrients can reduce hair shedding.
78 citations
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January 2017 in “Skin appendage disorders” Biotin supplements may improve hair and nail growth in people with certain deficiencies or conditions, but there's not enough evidence to recommend it for healthy individuals.
70 citations
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June 2010 in “Clinics in Dermatology” Certain groups may need vitamin supplements to improve hair health and prevent other health problems.
14 citations
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April 2000 in “Animal Science/Animal science” Nutrients like vitamins, copper, zinc, and amino acids are crucial for healthy hair and wool growth.
13 citations
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January 2019 in “Journal of the American Academy of Dermatology” Most people using biotin don't see skin improvements, and it may affect lab tests, so doctors shouldn't suggest it without confirming a deficiency.
11 citations
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June 2020 in “Russian Open Medical Journal” Lower ferritin and serum iron levels may be linked to melasma.
10 citations
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August 2021 in “Journal of Cosmetic Dermatology” Most patients with telogen effluvium had low iron and vitamin D levels; iron supplements were commonly prescribed.
8 citations
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January 2019 in “Chirurgia” Bariatric surgery is safe and effective for treating adolescent obesity.