34 citations
,
June 2020 in “British journal of dermatology/British journal of dermatology, Supplement” Frontal fibrosing alopecia is linked to increased immune system activity and reduced stem cells, suggesting early treatment targeting this pathway might prevent hair follicle damage.
1 citations
,
July 2020 in “Revista Cereus” Using growth factors with microneedling is effective for treating hair loss.
1 citations
,
January 2014 Crataegus pinnatifida extract promotes hair growth in mice.
135 citations
,
October 1999 in “Journal of Cell Science” Overexpressing PKCα in mice skin increases inflammation but doesn't affect tumor growth.
91 citations
,
May 1972 in “Journal of Biological Chemistry” Transglutaminases work through a ping-pong mechanism, and human plasma and platelet transglutaminases have similar catalytic subunits.
22 citations
,
December 2015 in “The journal of investigative dermatology/Journal of investigative dermatology” A mouse gene mutation increases the risk of skin cancer.
20 citations
,
August 2015 in “International Journal of Molecular Medicine” Human placental extract may help hair growth by affecting certain cell signals and could be more effective with minoxidil.
3 citations
,
January 2021 in “Plastic and Aesthetic Research” Hair loss reduces hair thickness and coverage, but drug treatments mainly revive dormant hairs rather than reverse thinning; patients often undervalue their hair loss severity.
1 citations
,
September 2017 in “Journal of Investigative Dermatology” Hair care products reduced hair roughness, a combination of Stemoxydine and Resveratrol increased hair density, fermented mackerel oil promoted hair growth, and genes TERT and Bmi-1 helped create new hair follicles.
Justicia procumbens extract may help prevent hair loss and improve hair thickness and shine in a type of hair loss condition.
January 2006 in “Advances in developmental biology” The Hairless gene is crucial for healthy skin and hair growth.
September 2004 in “Experimental Dermatology” Stress increases nerve growth factor, causing hair loss in mice.
10 citations
,
January 2016 in “Planta Medica” Formononetin, found in red clover plants, can promote hair regrowth and reduce hair loss by preventing cell death.
September 1997 in “JEADV. Journal of the European Academy of Dermatology and Venereology/Journal of the European Academy of Dermatology and Venereology” Anti-IL-1 treatments might help with certain types of hair loss in people with high inflammation.
1 citations
,
July 2022 in “Journal of dermatology” Disrupted citric acid metabolism stops hair growth.
Baricitinib may reactivate trichilemmal cysts in people with a history of these cysts.
January 1999 in “Journal of S C C J” Certain growth factors regulate hair growth cycles, male hormones affect hair cycles, and drugs like Minoxidil and Finasteride can stimulate hair growth and inhibit male pattern baldness respectively.
January 2020 in “Journal of Genetics and Gene Therapy” The combination of hair follicle stem cells and PRP shows promise for treating hair loss in Asian men and women.
11 citations
,
July 2012 in “Experimental dermatology” Innate immunity genes in hair follicle stem cells might have new roles beyond traditional immune functions.
1 citations
,
May 2021 in “Research Square (Research Square)” Micro-injury can help regrow hair and repigment vitiligo by activating specific cells.
117 citations
,
April 2008 in “Developmental biology” Ectodysplasin inhibits Wnt signaling to help form hair follicles.
30 citations
,
January 2014 in “Journal of Controlled Release” This method is effective for needle-free HIV-1 vaccination by activating immune responses in the skin.
6 citations
,
March 2009 in “Pigment Cell & Melanoma Research” A sphingolipid from human placenta may help treat vitiligo by activating melanocyte stem cells.
4 citations
,
April 2025 in “Antioxidants” Alpha-ketoglutarate protects rabbit skin cells from oxidative damage by activating a specific cell pathway.
September 2025 in “Stem Cells Translational Medicine” Lithium chloride-treated stem cell exosomes boost hair growth by activating a specific pathway.
May 2025 in “Journal of Traditional Chinese Medical Sciences” Stellera chamaejasme L. extract promotes hair growth by activating hair growth genes.
CRH causes hair loss by reducing cell survival in hair follicles.
120 citations
,
November 2014 in “Biological Reviews” The telogen phase of hair growth is active and important for preparing hair follicles for regeneration, not just a resting stage.
March 2024 in “Bioactive Materials” New treatment using engineered nanovesicles in hydrogel improves hair growth by repairing hair follicle cells in a mouse model of hair loss.
3 citations
,
November 2021 in “Journal of The American Academy of Dermatology” Androgenetic alopecia, a genetic disorder affecting up to 50% of adults, is caused by an excessive response to androgens leading to hair follicle shrinkage. Treatments include FDA-approved drugs, other therapies like low-dose oral minoxidil, and hair transplantation.