March 2026 in “Frontiers in Medicine” Different types of alopecia cause hair loss due to immune system issues, with some allowing regrowth and others causing permanent loss.
November 2025 in “Skin Appendage Disorders” Fibrosis contributes to hair loss in androgenetic alopecia, and targeting it may improve treatment.
November 2025 in “Journal of Investigative Dermatology” Hair follicle stem cells help maintain skin health after injury.
Combining anti-androgenic, anti-inflammatory, and anti-fibrotic treatments may improve hair loss outcomes.
Combining anti-androgenic, anti-inflammatory, and anti-fibrotic treatments may improve hair loss outcomes, but more testing is needed.
June 2024 in “Georgetown Scientific Research Journal” Bleomycin injections in mice cause skin thickening and hair loss.
A high fat lard diet may protect against skin fibrosis and affect hair growth.
September 2023 in “Frontiers in medicine” The mTOR signaling pathway is crucial for hair health and targeting it may lead to new hair loss treatments.
September 2022 in “The American journal of dermatopathology/American journal of dermatopathology” Sunscreen particles were not found in inflamed or fibrotic areas of skin in FFA patients, suggesting no direct link to the disease.
July 2022 in “JEADV Clinical Practice” The document concludes that different types of permanent hair loss conditions are related and early treatment is key to preventing further damage.
August 2021 in “Case Reports” A woman thought to have rosacea was actually suffering from Frontal Fibrosing Alopecia, a hair loss condition. Despite treatment, her condition didn't change, showing the importance of accurate early diagnosis.
July 2021 in “British Journal of Dermatology” A woman with systemic sclerosis developed a unique scarring hair loss combining features of systemic sclerosis and frontal fibrosing alopecia.
6 citations
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January 2019 in “The American Journal of Dermatopathology” The conclusion is that fat tissue in the skin is a new finding in Frontal fibrosing alopecia and may contribute to hair follicle and muscle degeneration.
5 citations
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September 2018 in “Acta histochemica” The mTOR pathway proteins are altered in the hair follicles of patients with Lichen Planopilaris and Frontal Fibrosing Alopecia.
June 2025 in “Journal of Ultrasound in Medicine” High-frequency ultrasound effectively evaluates and diagnoses frontal fibrosing alopecia.
April 2023 in “JAAD international” Patients with Frontal fibrosing alopecia in Morocco often have skin conditions and thyroid disorders.
April 2023 in “Journal of Investigative Dermatology” Being allergic to linalool, a common fragrance ingredient, might contribute to developing frontal fibrosing alopecia.
February 2021 in “Cureus” A woman's hair loss was initially misdiagnosed as scarring hair loss but was actually a treatable autoimmune hair loss.
April 2018 in “Journal of Investigative Dermatology” Macrophages are more involved in Lichen planopilaris than in Frontal fibrosing alopecia.
December 2015 in “Actas Dermo-Sifiliográficas” Hair transplantation for Frontal Fibrosing Alopecia may work if the disease is inactive for 2 years and with ongoing treatment to maintain results.
May 2015 in “Journal of the American Academy of Dermatology” Certain drugs and supplements may contribute to hair loss in the frontal hairline in older women.
September 2013 in “Hair transplant forum international” The document says doctors should identify and treat Frontal fibrosing alopecia medically before considering surgery, as treatments often don't work well.
23 citations
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May 2017 in “Journal of the American Academy of Dermatology” FFA patients have fewer melanocytes and thinner skin compared to others.
22 citations
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April 2013 in “International Journal of Dermatology” Frontal fibrosing alopecia can occur with lichen planus pigmentosus, needing careful diagnosis and treatment.
2 citations
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June 2024 in “Skin Appendage Disorders” Trichoscopy helps diagnose frontal fibrosing alopecia in Caucasians, but more research is needed.
September 2019 in “The journal of investigative dermatology/Journal of investigative dermatology” Eyebrow hair transplants in patients with frontal fibrosing alopecia may look good at first but often lose the new hair after a few years.
February 2011 in “Journal of the American Academy of Dermatology” A 60-year-old man with a long-term balding condition also developed a rare hair loss condition usually seen in postmenopausal women.
145 citations
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November 2018 in “Nature Communications” The Sonic hedgehog pathway is crucial for new hair growth during mouse skin healing.
April 2019 in “Journal of Investigative Dermatology” Activating the Sonic hedgehog pathway can help regenerate hair follicles during wound healing in mice, potentially improving regeneration after injury.
46 citations
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January 2015 in “Journal of The American Academy of Dermatology” Trichoscopy helps diagnose and assess the severity of Frontal Fibrosing Alopecia.