88 citations
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December 2018 in “Advanced Healthcare Materials” Layer-by-Layer self-assembly is promising for biomedical uses like tissue engineering and cell therapy, but challenges remain in material safety and process optimization.
81 citations
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September 2013 in “PLoS ONE” Primary and secondary hair follicle cells in Cashmere goats have different gene expressions affecting hair growth and size.
77 citations
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March 2014 in “Cold Spring Harbor Perspectives in Medicine” Fat cells are important for healthy skin, hair growth, and healing, and changes in these cells can affect skin conditions and aging.
76 citations
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March 2005 in “Cancer Research” Doxorubicin can block blood vessels from hair follicles, reducing skin tumor growth.
75 citations
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March 2014 in “Journal of Investigative Dermatology” Aging mice have slower hair regeneration due to changes in signal balance, but the environment, not stem cell loss, controls this, suggesting treatments could focus on environmental factors.
75 citations
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May 1986 in “Clinics in endocrinology and metabolism” Male hormones are important for hair and oil gland development and can cause conditions like excessive hair growth and acne.
71 citations
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February 2020 in “Journal of Translational Medicine” Progress has been made in skin and nerve regeneration, but more research is needed to improve methods and ensure safety.
68 citations
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December 2011 in “Journal of Investigative Dermatology” Sox2-positive dermal papilla cells have unique characteristics and contribute more to skin and hair follicle formation than Sox2-negative cells.
68 citations
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March 1965 in “The BMJ” Hormones and genetics affect hair growth and patterns, with some changes reversible and others not.
66 citations
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June 2015 in “Aesthetic Plastic Surgery” Platelet preparations generally show positive effects on wound healing and facial rejuvenation, but more thorough research is needed to confirm their effectiveness.
66 citations
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May 2012 in “Scientific Reports” Scientists successfully created and transplanted bioengineered hair follicles that function like natural ones, suggesting a new treatment for hair loss.
65 citations
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July 2020 in “Science Advances” Dermal exosomes with miR-218-5p boost hair growth by controlling β-catenin signaling.
63 citations
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April 2010 in “Development” Compartmentalized organization might be crucial for stem cells to effectively respond to growth or injury.
62 citations
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July 1993 in “Journal of Investigative Dermatology” Hair growth is influenced by interactions between skin layers, growth factors, and hormones, but the exact mechanisms are not fully understood.
58 citations
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January 2006 in “Skin Pharmacology and Physiology” High levels of testosterone and 5α-DHT can lead to cell death in cells important for hair growth.
55 citations
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March 2012 in “Journal of Investigative Dermatology” Research on epidermal stem cells has advanced significantly, showing promise for improved clinical therapies.
55 citations
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October 2008 in “American Journal Of Pathology” mIGF-1 in skin cells speeds up wound healing and hair growth in mice without harmful effects.
55 citations
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October 1992 in “Archives of Dermatology” Loose Anagen Hair Syndrome is a hereditary condition causing hair loss in children due to abnormal hair follicles.
53 citations
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October 2012 in “The FASEB Journal” Bimatoprost, a glaucoma medication, may also help treat hair loss.
45 citations
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March 2020 in “ACS Applied Materials & Interfaces” The new biomaterial inspired by ancient Chinese medicine effectively promotes hair growth and heals wounds in burned skin.
45 citations
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June 2003 in “Journal of Investigative Dermatology Symposium Proceedings” Understanding hair follicles through various models can help develop new treatments for hair disorders.
44 citations
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July 2016 in “Stem Cells Translational Medicine” Scientists discovered that certain stem cells from mice and humans can be used to grow new hair follicles and skin glands when treated with a special mixture.
44 citations
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August 2008 in “Archives of Dermatology” Trichoscopy is a non-invasive way to diagnose hair and scalp problems without needing hair samples.
43 citations
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April 2021 in “Angiogenesis” Lymphatic vessels develop from various cell types and mechanisms, not just veins.
43 citations
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March 2009 in “Journal of Cellular and Molecular Medicine” TGF-β2 plays a key role in human hair growth and development.
42 citations
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May 2016 in “Annual Review of Cell and Developmental Biology” Fat cells are important for tissue repair and stem cell support in various body parts.
41 citations
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September 2010 in “Journal of dermatological science” Bone marrow and umbilical cord stem cells can help grow new hair.
41 citations
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June 2006 in “Journal of Investigative Dermatology” Beard and scalp hair cells have different gene expressions, which may affect beard growth characteristics.
40 citations
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March 2018 in “Aesthetic Surgery Journal” New treatment combining PRP and SVF increases hair density in 6-12 weeks for androgenetic alopecia patients.
39 citations
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August 2022 in “Cell Death and Disease” DA-MeHA hydrogel effectively aids stem cell-based skin regeneration.