77 citations
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May 2012 in “Expert Opinion on Emerging Drugs” New treatments for male hypogonadism are effective and should be personalized.
76 citations
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July 2019 in “Cellular and Molecular Life Sciences” Stem cells are crucial for tissue growth, cancer treatment, and disease modeling, but challenges remain in clinical use.
73 citations
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April 2013 in “Stem cells” LGR5 helps maintain corneal cell characteristics and prevents unwanted changes by controlling specific cell signaling pathways.
72 citations
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April 2008 in “The Journal of urology/The journal of urology” Dutasteride and finasteride do not significantly affect bone density, blood fats, or blood production, but slightly lower PSA levels and minimally impact sexual function in healthy young men.
70 citations
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March 2016 in “Urologic Clinics of North America” The document explains how the male reproductive system works, its role in making testosterone, and how conditions like obesity can disrupt it, leading to low testosterone and fertility issues.
68 citations
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July 2016 in “Dermatology and Therapy” Light and laser therapies show promise for treating Acne Keloidalis Nuchae, but more research is needed.
57 citations
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December 2021 in “Nature Communications” Non-canonical Wnt signaling helps intestinal stem cells move to injury sites for tissue repair.
57 citations
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January 1986 in “The Prostate” The document suggests that targeting the hormone DHT could be a more effective treatment for prostate cancer than targeting testosterone.
51 citations
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January 2006 in “Wound Repair and Regeneration” MRL/MpJ mice's skin wounds heal with scars, unlike their ear wounds which can regenerate.
47 citations
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February 2021 in “Pharmacological research” Exosomes can improve skin health and offer new treatments for skin repair and rejuvenation.
44 citations
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July 2011 in “Dermato-endocrinology” Thyroid hormone affects skin health, with too little causing rough, pale skin and too much leading to smooth, thin skin, and may also impact wound healing and skin conditions.
36 citations
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September 2009 in “Journal of Cellular and Molecular Medicine” New treatments targeting skin stem cells show promise for skin repair, anti-aging, and cancer therapy.
32 citations
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January 2005 in “Advances in Biochemical Engineering / Biotechnology” Fetal wounds heal without scarring because of different biological factors, which could help improve adult wound healing.
31 citations
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May 2012 in “European Journal of Dermatology” Menopause affects hair and skin; more research needed for treatment.
26 citations
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August 1971 in “Journal of Morphology” Lizards can regrow their tail scales with the same structure, distribution, and gender-specific features as the original ones, and this unique ability is not seen in adult mammals.
25 citations
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May 2016 in “Progress in Biophysics & Molecular Biology” R-spondins and their receptors help increase bone growth and may be used to treat bone loss diseases.
25 citations
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March 2000 in “Journal of Endocrinological Investigation” Testosterone therapy aims to treat hormone deficiencies and various conditions safely and effectively, but requires careful patient monitoring due to potential side effects.
24 citations
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November 2016 in “Molecular Medicine Reports” Hormonal imbalances, often indicating conditions like PCOS, are common in women with hard-to-treat acne, and a treatment approach addressing these imbalances may be needed.
23 citations
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August 2005 in “Expert opinion on pharmacotherapy” New treatments for low male hormones improved sexual function and mood but had unclear risks, especially for older men.
21 citations
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January 2019 in “Experimental dermatology” Light therapy using helium-neon lasers can help restore skin color in vitiligo by promoting skin cell growth and movement.
21 citations
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March 2018 in “Experimental Dermatology” The guide explains how to study human skin fat cells and their tissue, aiming to improve research and medical treatments.
20 citations
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April 1999 in “British journal of plastic surgery” Ruby laser hair removal significantly reduces hair density.
18 citations
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July 2021 in “Molecular Medicine Reports” The WNT signaling pathway is crucial for mesenchymal stem cells' function and therapy success.
18 citations
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December 2014 in “Obstetrics and Gynecology Clinics of North America” Losing 5-10% body weight can improve PCOS symptoms, letrozole is better than clomiphene for fertility, and managing weight and blood sugar is important to reduce pregnancy complications.
18 citations
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April 2014 in “Stem cells” The study found stem cells in minor salivary glands that can differentiate and are involved in tumor formation when exposed to tobacco.
16 citations
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July 2012 in “Current pharmaceutical biotechnology” New treatments for skin conditions related to the sebaceous gland are being developed based on current research.
15 citations
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August 1998 in “Australasian journal of dermatology” The document concludes that various cosmetic and drug treatments are available for hirsutism, and some new drugs show promise.
14 citations
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January 2018 in “Advances in Clinical Chemistry” The document concludes that hormonal biomarkers are key for diagnosing hyperandrogenemia in women and hypogonadism in men.
13 citations
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February 2020 in “Cold Spring Harbor Perspectives in Biology” New methods have helped find cells that create other cells in the body.
13 citations
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February 2010 in “Stem Cell Reviews and Reports” Stem cells compete for space using cell adhesion, and mutations can affect their competitive success, with implications for tissue health and disease.