990 citations
,
October 1999 in “Development” Activated LEF/TCF complexes are crucial for hair development and cycling.
949 citations
,
January 2001 in “Cell” Adult mouse skin contains stem cells that can create new hair, skin, and oil glands.
520 citations
,
February 2001 in “Journal of Clinical Investigation” VEGF helps hair grow and determines follicle size by increasing blood vessel growth.
125 citations
,
August 1992 in “Development” Implanted dermal papillae can induce hair growth in rat ear wounds.
117 citations
,
November 2006 in “Experimental Dermatology” The article concludes that the wool follicle is a valuable model for studying tissue interactions and has potential for genetic improvements in wool production.
116 citations
,
January 1957 in “Australian Journal of Agricultural Research” Certain hair follicle traits in Merino sheep may be inherited.
95 citations
,
March 2009 in “Differentiation” Gene expression in wool follicles changes with growth cycles, offering insights into wool and human hair growth.
72 citations
,
January 1983 in “The Anatomical Record” Epidermal growth factor delays skin and hair development in mice.
67 citations
,
December 1990 in “The journal of cell biology/The Journal of cell biology” Researchers found genes for cysteine-rich proteins that form the protective layer of hair in humans and sheep.
61 citations
,
October 1996 in “Development” Hair growth can be stimulated by combining certain skin cells, which can rejuvenate old cells and cause them to specialize in hair follicle creation.
57 citations
,
April 2009 in “Differentiation” SDF-1/CXCL12 and its receptor CXCR4 are crucial for melanocyte movement in mouse hair follicles.
56 citations
,
August 1994 in “PubMed” Prolactin and melatonin can stimulate hair growth in Cashmere goat hair follicles, but melatonin may reduce follicle viability over time.
47 citations
,
December 2003 in “Journal of Investigative Dermatology” DS cells in hair follicles can help form and restore hair, especially in hair loss conditions.
46 citations
,
July 2007 in “Journal of comparative neurology” Manatee whiskers are specially adapted for touch in water.
46 citations
,
November 1998 in “Experimental Cell Research” K15 gene is mainly active in the basal layers of hair follicles and epithelia, aiding early skin cell development.
45 citations
,
August 2018 in “Stem Cells International” Stem cells, especially from fat tissue and Wharton's jelly, can potentially regenerate hair follicles and treat hair loss, but more research is needed to perfect the treatment.
43 citations
,
December 2008 in “Molecular biology of the cell” Disrupting Smad4 in mouse skin causes early hair follicle stem cell activity that leads to their eventual depletion.
41 citations
,
May 2001 in “PubMed” Different thicknesses of hair strands can indicate the severity of hair thinning.
36 citations
,
May 2016 in “Biomaterials” Endo-HSE helps grow hair-like structures from human skin cells in the lab.
30 citations
,
May 2016 in “International Journal of Cosmetic Science” Hair loss in women links to inflammation around hair follicles.
30 citations
,
June 2008 in “Dermatologic Surgery” The SAFE System may improve hair transplant results but isn't suitable for everyone.
29 citations
,
July 1993 in “The journal of investigative dermatology/Journal of investigative dermatology” Hair follicle development involves complex interactions between skin layers and cells, but many details are still unknown.
28 citations
,
July 1993 in “The journal of investigative dermatology/Journal of investigative dermatology” Dermal papilla cells are crucial for hair growth and can induce new hair follicles.
27 citations
,
July 2018 in “Journal of optometry” Eyelashes protect the eyes, but more research is needed to understand how.
26 citations
,
December 1999 in “Journal of Investigative Dermatology” Certain genes are linked to wool follicle structure and function, but not hair cycle regulation.
25 citations
,
June 2022 in “Developmental cell” Overactivating Hedgehog signaling makes hair follicle cells in mice grow hair faster and create more follicles.
24 citations
,
May 2009 in “The FASEB Journal” Akt2 and SGK3 are both important for normal hair growth and development.
24 citations
,
April 2006 in “Journal of the American Academy of Dermatology” Heat shock protein 27 is more present in the active growth phase of human scalp hair follicles.
22 citations
,
October 2018 in “Aesthetic Plastic Surgery” Understanding hair follicle biology and stem cell control could lead to new hair loss treatments.
19 citations
,
July 1993 in “The journal of investigative dermatology/Journal of investigative dermatology” Dermal-epidermal interactions are crucial for hair growth and maintenance.