July 2023 in “British journal of dermatology/British journal of dermatology, Supplement” Aging changes scalp cells, possibly affecting hair health in older women.
8 citations
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November 2018 in “Australasian Journal of Dermatology” Frontal fibrosing alopecia in families shows similar signs to individual cases and may have a genetic link.
December 2024 in “Brazilian Journal of Health Review” Early diagnosis of alopecia frontal fibrosante is crucial, but treatment remains controversial and varies.
Lack of Fgf21 slows hair growth by affecting gene interactions.
17 citations
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June 2016 in “Archives de Pédiatrie” Frontal fibrosing alopecia can occur in children, not just postmenopausal women.
24 citations
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September 2002 in “Dermatologic Surgery” The study found that hair follicles are above muscle connections in the scalp, which may help protect stem cell areas.
July 2015 in “Journal of the Dermatology Nurses’ Association” A 66-year-old woman experienced hair loss due to Frontal Fibrosing Alopecia, a condition with no consistently effective treatment, but it usually stabilizes over time. More research is needed for better understanding and treatment options.
August 2023 in “Cell Proliferation” Human cells in plasma-derived gels can potentially mimic hair follicle environments, improving hair regeneration therapies.
4 citations
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January 2020 in “Skin appendage disorders” A woman with an unusual pattern of hair loss was confirmed to have Frontal Fibrosing Alopecia and treated with specific medications.
Protein profiling of forehead skin can help distinguish between frontal fibrosing alopecia and androgenetic alopecia.
2 citations
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April 2017 in “Actas Dermo-Sifiliográficas” Best treatment for Frontal Fibrosing Alopecia is 5-alpha-reductase inhibitors and intralesional corticosteroids.
August 2016 in “Journal of Investigative Dermatology” Human hair follicles have a scent receptor that can influence hair growth.
April 2017 in “Journal of Investigative Dermatology” Scientists created a tiny, 3D model of a hair follicle that grows and acts like a real one.
14 citations
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January 2014 in “Indian Journal of Dermatology Venereology and Leprology” Frontal fibrosing alopecia can affect men's beards and leads to permanent hair loss.
January 2022 in “SSRN Electronic Journal” LncRNA RP11-818024.3 helps hair growth and recovery in hair loss by boosting cell survival and reducing cell death.
27 citations
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February 2017 in “Clinical, Cosmetic and Investigational Dermatology” New compounds were found to help increase hair growth and decrease hair loss.
9 citations
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April 2019 in “Bioscience, biotechnology, and biochemistry” Ten miRNAs may play key roles in starting secondary hair follicle development in sheep foetuses.
72 citations
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October 2009 in “The FASEB journal” TRH stimulates human hair growth and extends the hair growth phase.
53 citations
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July 2002 in “Journal of Investigative Dermatology” The Dfl mutation in mice causes poor sebaceous gland function and complete hair loss.
April 2023 in “Journal of Investigative Dermatology” Being allergic to linalool, a common fragrance ingredient, might contribute to developing frontal fibrosing alopecia.
April 2023 in “World Journal Of Advanced Research and Reviews” Cosmetic products or emotional factors might contribute to Frontal Fibrosing Alopecia, and trichoscopy is useful for diagnosis.
86 citations
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July 2002 in “Clinical and Experimental Dermatology” FPHL is a common, age-related, genetic hair loss with unclear causes and limited treatment options.
166 citations
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April 2012 in “Journal of The American Academy of Dermatology” Mostly postmenopausal Caucasian women get Frontal Fibrosing Alopecia, which often includes eyebrow loss and has limited treatment success.
February 2022 in “Research Square (Research Square)” LGR5 is a marker found in hair follicle stem cells in various species and is important for hair growth and skin repair.
11 citations
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September 2019 in “The journal of investigative dermatology/Journal of investigative dermatology” A specific group of skin stem cells was found to help maintain hair follicle cells.
1 citations
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November 2004 in “Hair transplant forum international” Hair restoration surgeons must understand the differences between CTE and FPHL for accurate diagnosis and treatment.
October 2012 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” Scientists used a special imaging technique to observe that hair follicle regeneration involves cell division and structural changes, mostly in the lower part of the follicle, and that the dermal papilla at the base is crucial for regrowth.
January 2026 in “Current Issues in Molecular Biology” FGF-7 helps hair grow by activating hair follicles and is a promising target for hair loss treatments.
25 citations
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December 2017 in “Facial Plastic Surgery” Combination therapy with steroids and pimecrolimus improved or stabilized hair loss in most patients with Frontal Fibrosing Alopecia, who also had a high rate of hypothyroidism.
Folicrex may help with hair growth and health but lacks clinical evidence.