research In vivo transcriptional governance of hair follicle stem cells by canonical Wnt regulators
Wnt signaling controls whether hair follicle stem cells stay inactive or regenerate hair.
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research Stem cell dynamics in the hair follicle niche
Stem cells in the hair follicle are regulated by their surrounding environment, which is important for hair growth.
research What’s Sex Got to Do With COVID-19? Gender-Based Differences in the Host Immune Response to Coronaviruses
Men generally have more severe COVID-19 cases and higher death rates than women due to biological differences.
research Resting no more: re‐defining telogen, the maintenance stage of the hair growth cycle
The telogen phase of hair growth is active and important for preparing hair follicles for regeneration, not just a resting stage.
research Wnt and Notch signaling pathway involved in wound healing by targeting c-Myc and Hes1 separately
Wnt and Notch signaling help wound healing by promoting cell growth and regulating cell differentiation.
research The hair cycle
The document concludes that the hair cycle is a complex process involving growth, regression, and rest phases, regulated by various molecular signals.
research Ferreting out stem cells from their niches
New methods have greatly improved our understanding of stem cell behavior and roles in the body.
research Corticosterone inhibits GAS6 to govern hair follicle stem-cell quiescence
Stress hormone corticosterone blocks a growth factor to slow down hair stem cell activity and hair growth.
research Identifying novel strategies for treating human hair loss disorders: Cyclosporine A suppresses the Wnt inhibitor, SFRP1, in the dermal papilla of human scalp hair follicles
Cyclosporine A may help treat hair loss by blocking a protein that inhibits hair growth.
research From neural crest cells to melanocytes: cellular plasticity during development and beyond
Melanocyte development from neural crest cells is complex and influenced by many factors, and better understanding could help treat skin disorders.
research Stem cell quiescence acts as a tumour suppressor in squamous tumours
Inactive hair follicle stem cells help prevent skin cancer.
research Emerging nonmetabolic functions of skin fat
Skin fat has important roles in hair growth, skin repair, immune defense, and aging, and could be targeted for skin and hair treatments.
research Lef1 Contributes to the Differentiation of Bulge Stem Cells by Nuclear Translocation and Cross-Talk with the Notch Signaling Pathway
Lef1 helps stem cells become hair cells by interacting with specific signaling pathways.
research Current Evidence for Clinical Efficacy of Platelet Rich Plasma in Aesthetic Surgery: A Systematic Review
The document concludes that the effectiveness of platelet rich plasma in aesthetic surgery is unclear due to inconsistent reporting and lack of objective measures in studies.
research Hirsutism and the Variable Response of the Pilosebaceous Unit to Androgen
Different women's hair and skin glands respond to hormones in varied ways, which can cause unwanted hair growth even with normal hormone levels, and more research is needed to treat this effectively.
research Lymphatic vessels interact dynamically with the hair follicle stem cell niche during skin regeneration in vivo
Lymphatic vessels are essential for hair follicle growth and skin regeneration.
research Xenobiotica-metabolizing enzymes in the skin of rat, mouse, pig, guinea pig, man, and in human skin models
Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.
research Live imaging of stem cells: answering old questions and raising new ones
Live imaging has advanced our understanding of stem cell behavior and raised new research questions.
research The Mesenchymal Niche of the Hair Follicle Induces Regeneration by Releasing Primed Progenitors from Inhibitory Effects of Quiescent Stem Cells
The study found that a specific area of the hair follicle helps start hair growth by reducing the blocking effects on certain cells and controlling growth signals.
research Stem cells and alopecia: a review of pathogenesis
Damaged hair follicle stem cells can cause permanent hair loss, but understanding their role could lead to new treatments.
research New onset of alopecia areata in a patient with SARS‐CoV‐2 infection: Possible pathogenetic correlations?
COVID-19 infection may trigger alopecia areata in some patients.
research LPA3, a unique G protein-coupled receptor for lysophosphatidic acid
LPA3 is crucial for embryo implantation and links LPA to prostaglandin signaling.
research Gata6 promotes hair follicle progenitor cell renewal by genome maintenance during proliferation
Gata6 is important for protecting hair growth cells from DNA damage and keeping normal hair growth.
research Wnt10b Promotes Differentiation of Mouse Hair Follicle Melanocytes
Wnt10b helps hair follicle cells mature and produce pigment.
research Resveratrol derivatives: a patent review (2009 – 2012)
New resveratrol-related compounds show promise for treating various health issues but need more research for clinical use.
research Symmetry breaking of tissue mechanics in wound induced hair follicle regeneration of laboratory and spiny mice
Tissue stiffness affects hair follicle regeneration, and Twist1 is a key regulator.
research Fisetin Promotes Hair Growth by Augmenting TERT Expression
Fisetin, a type of polyphenol, may help hair grow by increasing certain protein activities in cells.
research RASopathic alopecia: Hair changes associated with vemurafenib therapy
Vemurafenib therapy can cause hair loss, but clobetasol propionate foam can help regrow hair.
research Targeted therapy in melanoma
New treatments for advanced skin cancer are improving patient outcomes, but drug resistance and finding the right treatment combinations are still big challenges.
research Human placental extract exerts hair growth-promoting effects through the GSK-3β signaling pathway in human dermal papilla cells
Human placental extract may help hair growth by affecting certain cell signals and could be more effective with minoxidil.