November 2024 in “Journal of Translational Internal Medicine” Exosomes from stem cells help hair regrowth by activating a specific signaling pathway.
Stem cell therapy shows promise for treating hair loss in androgenetic alopecia.
4 citations
,
July 2025 in “Frontiers in Immunology” Early intervention with JAK inhibitors may prevent alopecia areata progression.
January 2014 in “Journal of Investigative Dermatology” Proteins like aPKC and PDGF-AA, substances like adenosine and ATP, and adipose-derived stem cells all play important roles in hair growth and health, and could potentially be used to treat hair loss and skin conditions.
211 citations
,
November 2018 in “Nature Cell Biology” Stem cells help heal skin wounds by moving and changing roles, working with other cells, and needing more research on their activation and behavior.
124 citations
,
February 2018 in “Nature Reviews Genetics” Stem cell plasticity is crucial for wound healing but can also contribute to cancer development.
66 citations
,
December 2013 in “Nature Cell Biology” Inactive hair follicle stem cells help prevent skin cancer.
56 citations
,
May 2017 in “Nature Cell Biology” Hair can regrow after certain stem cells are lost because other stem cells can take over their role.
46 citations
,
July 1988 in “Journal of The American Academy of Dermatology” Hormone imbalances can cause specific skin changes, which may help in early detection of endocrine disorders.
45 citations
,
August 2013 in “Facial Plastic Surgery Clinics of North America” Using sharp tools and the right techniques in hair transplant surgery leads to less damage to hair follicles.
38 citations
,
January 2016 in “Cell Death and Disease” The TCL1 transgenic mouse model is useful for understanding human B-cell leukemia and testing new treatments.
36 citations
,
August 2011 in “Experimental Dermatology” Eccrine sweat gland's clear cells likely cause excessive sweating in hyperhidrosis.
35 citations
,
January 2018 in “Skin pharmacology and physiology” Nanoemulsion creams with certain enhancers can greatly increase caffeine delivery through skin.
34 citations
,
October 2014 in “European journal of pharmaceutics and biopharmaceutics” The new drug delivery system releases the drug better in sebum and targets follicles more effectively than the conventional cream.
32 citations
,
March 2013 in “Journal of Pharmaceutical Sciences” Iontophoresis improves minoxidil delivery for alopecia treatment.
31 citations
,
September 2014 in “Journal of Pharmaceutical Sciences” Using a special laser can improve how well hair loss treatments get into the skin and hair follicles.
29 citations
,
December 2005 in “BioEssays” Wnt/ß-catenin signaling is crucial for regulating skin stem cells and hair growth, with the right levels and timing needed for proper function.
20 citations
,
September 1978 in “International Journal of Dermatology” Hair growth is influenced by factors like genetics and nutrition, and more research is needed to understand hair loss and growth mechanisms.
19 citations
,
July 2020 in “Journal of drug delivery science and technology” Nanoemulsions with minoxidil and clove oil effectively target hair follicles for better alopecia treatment.
19 citations
,
December 2016 in “PLOS ONE” Early-stage skin cells help regenerate hair follicles, with proteins SDF1, MMP3, biglycan, and LTBP1 playing key roles.
18 citations
,
January 2008 in “Journal of The American Academy of Dermatology” Certain proteins and their receptors are more active during the growth phase of human hair and could be targeted to treat hair disorders.
16 citations
,
September 2016 in “Experimental Dermatology” Two-photon microscopy effectively tracks live stem cell activity in mouse skin with minimal harm and clear images.
15 citations
,
November 2020 in “Pharmaceutics” Tofacitinib nanoparticles can safely and effectively treat alopecia areata by targeting hair follicles.
14 citations
,
March 2017 in “Plastic and reconstructive surgery. Global open” Hair follicle damage happens during hair transplants and can impact success; better surgical methods are needed.
11 citations
,
May 2010 in “Journal of Medicinal Chemistry” A new compound was created in 2010 that can control oil production when applied to the skin, and its effects are completely reversible after two weeks.
10 citations
,
January 2013 in “Journal of skin cancer” PKC ε increases hair follicle stem cell turnover and may raise skin cancer risk.
9 citations
,
July 2017 in “Journal of Drug Delivery Science and Technology” Scientists developed a new method to deliver alopecia treatment directly to hair follicles, which could be a promising treatment for hair loss and other hair diseases.
9 citations
,
January 2017 in “Elsevier eBooks” Skin's epithelial stem cells are crucial for repair and maintenance, and understanding them could improve treatments for skin problems.
9 citations
,
January 2021 in “RSC Advances” Non-thermal plasma helps hair grow by improving the area around hair follicles.
9 citations
,
March 2019 in “Scientific reports” Temporary ROS production in cultured human hair follicles promotes growth and stem cell activation.