260 citations
,
December 2012 in “Cold Spring Harbor Perspectives in Biology” Wnt signaling is crucial for skin development and health, and its disruption can cause skin diseases.
45 citations
,
May 2003 in “Journal of Cell Science” α3β1-integrin is crucial for maintaining normal hair follicle shape and function but not needed for the development of the surrounding skin.
19 citations
,
November 2001 in “Journal of Investigative Dermatology Symposium Proceedings” Human hair follicles can regenerate and recover after severe injury by going through a brief abnormal resting phase before growing again.
2 citations
,
November 2012 in “InTech eBooks” The document concludes that sex hormones are crucial for mammalian reproduction, health, and behavior, and require more research for therapeutic use.
1 citations
,
March 2018 in “bioRxiv (Cold Spring Harbor Laboratory)” The hair treatment made hair grow faster and thicker and strengthened the hair roots.
December 2025 in “Italian Journal of Anatomy and Embryology” Understanding embryologic layers improves skin disorder diagnosis and supports developing targeted therapies.
November 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” Disrupted cholesterol production impairs hair follicle stem cells, leading to hair loss.
September 2013 in “Experimental Dermatology” The document concluded that stem cells are crucial for skin repair, regeneration, and may help in developing advanced skin substitutes.
25 citations
,
November 2008 in “Facial Plastic Surgery” Dr. Michael Beehner recommends a personalized, careful approach to hairline design in hair replacement surgery for a natural look.
January 2016 in “Georg Thieme Verlag eBooks” More East Asians are accepting and getting facial plastic surgery, with a focus on natural-looking results and using both surgical and nonsurgical methods.
January 2012 in “Elsevier eBooks” Hair loss can cause emotional and social issues, and various treatments, including medication, surgery, and psychological support, are needed.
129 citations
,
May 2015 in “Cell Stem Cell” Different types of stem cells exist within individual skin layers, and they can adapt to damage, transplantation, or tumor growth. These cells are regulated by their environment and genetic factors. Tumor growth is driven by expanding, genetically altered cells, not long-lived mutant stem cells. There's evidence of cancer stem cells in skin tumors. Other cells, bacteria, and genetic factors help maintain balance and contribute to disease progression. A method for growing mini organs from single cells has been developed.
127 citations
,
December 2007 in “Journal of Investigative Dermatology” Mice hair growth patterns get more complex with age and can change with events like pregnancy or injury.
42 citations
,
January 2014 in “Cold Spring Harbor Perspectives in Medicine” Hair growth is influenced by various body and external factors, and neighboring hairs communicate to synchronize regeneration.
36 citations
,
November 2009 in “European Radiology” The study found that women with PCOS have more and larger ovarian follicles and differences in ovarian structure, but these features alone can't always diagnose PCOS.
19 citations
,
October 2019 in “Dermatology Practical & Conceptual” Dermoscopy now helps diagnose various skin, hair, and nail issues, improving patient care and treatment understanding.
4 citations
,
October 2012 in “Expert Review of Dermatology” Dermoscopy greatly improves melanoma diagnosis and reduces unneeded surgeries.
September 2025 in “Medical Materials Research” Microneedles offer a painless, precise, and versatile method for drug delivery and disease treatment.
January 2025 in “International Journal of Pharmacognosy and Life Science” Herbal treatments like Aloe vera, Bhringraj, Neem, Tea tree oil, Amla, and Hibiscus are promising for safer, effective hair care.
349 citations
,
January 2005 in “The FASEB journal” Human skin can make serotonin and melatonin, which help protect and maintain it.
5 citations
,
January 2019 in “Elsevier eBooks” Current therapies cannot fully regenerate adult skin without scars; more research is needed for scar-free healing.
10 citations
,
May 2025 in “Nutrition & Metabolism” Metabolic syndrome is linked to skin diseases, requiring integrated treatment and monitoring.
March 2026 in “Preprints.org” Robotic systems in cosmetic surgery are promising but need more development and research.
Aesthetic rehabilitation techniques can improve life quality and wellbeing for disabled patients.
May 2015 in “Hair transplant forum international” Androgenetic alopecia causes hair loss by shrinking hair follicles due to androgens, with the connection between the muscle and hair follicle determining if the loss is reversible.
November 2023 in “Journal of Investigative Dermatology” EGFR-targeted cancer therapy can cause skin issues starting at hair follicles, leading to inflammation.
November 2025 in “Journal of Clinical Medicine” Alopecia areata patients should have eye check-ups due to increased risk of eye problems.
September 2025 in “Journal of Cutaneous and Aesthetic Surgery” Scalp micropigmentation improves appearance and satisfaction in scarring alopecia but may require repeat sessions.
31 citations
,
January 2009 in “Autoimmunity Reviews” Damage to hair follicle stem cells causes permanent hair loss and scarring in cutaneous lupus erythematosus.
May 2025 in “Frontiers in Pharmacology” New treatments are needed for non-scarring alopecia due to current limitations.