April 2019 in “The journal of investigative dermatology/Journal of investigative dermatology” Disrupting the Tsc2 gene in certain cells leads to thicker skin, larger hair, and changes in hair growth signaling, which can be partly reversed with specific treatment.
20 citations
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April 2014 in “Dermatologic Therapy” Sulfotransferase in hair follicles helps predict how well minoxidil works for female hair loss.
9 citations
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February 2022 in “BMC Genomics” Melatonin affects gene expression in goat hair follicles, potentially increasing cashmere production.
TLR2 is crucial for hair growth and regeneration, and boosting it can help prevent hair loss.
January 2011 in “Hispania Judaica bulletin” Mechanical forces are crucial for hair regeneration in skin organoids.
176 citations
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April 2011 in “Science” Hair stem cell regeneration is controlled by signals that can explain different hair growth patterns and baldness.
6 citations
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February 2014 in “Experimental Dermatology” Hair follicle regeneration is possible but challenging, especially in humans, due to the need for specific cells and a better understanding of how they signal growth.
1010 citations
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August 2000 in “Cell” Hair follicle stem cells can form both hair follicles and skin.
9 citations
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March 2019 in “Scientific reports” Temporary ROS production in cultured human hair follicles promotes growth and stem cell activation.
September 2019 in “Journal of Investigative Dermatology” Researchers developed a new method to deliver molecules to hair follicles to manage hair growth without damaging surrounding skin.
8 citations
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July 2019 in “Cell Proliferation” Researchers found a way to turn skin cells into cells that can grow new hair.
405 citations
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January 2004 in “Journal of Investigative Dermatology” Hair follicle size and distribution vary significantly across different body sites.
February 2001 in “Chinese Journal of Dermatology” Epidermal growth factor (EGF) boosts the growth of hair follicle cells.
51 citations
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February 2009 in “Journal of dermatological science” Pitx2 helps outer root sheath cells differentiate but can't start hair growth on its own.
29 citations
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January 2021 in “Journal of nanobiotechnology” Tiny particles from brain cells help hair grow by targeting a specific hair growth pathway.
1 citations
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May 2023 in “PubMed” A certain type of skin cell, marked by EGFR, produces a lot of IGF1 and helps hair follicles grow back faster.
19 citations
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July 2011 in “Microscopy and Microanalysis” The hair follicle bulge is an important area for adult stem cells involved in hair growth and repair, with potential for medical use needing more research.
3 citations
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November 2022 in “Frontiers in molecular biosciences” Plasmalogens activate a channel in cells that may stimulate hair growth.
April 2018 in “The journal of investigative dermatology/Journal of investigative dermatology” Certain immune cells, when activated by specific signals, can encourage hair growth.
24 citations
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September 2019 in “Experimental cell research” BMP2 helps hair follicle stem cells become specialized by increasing PTEN, which causes autophagy.
103 citations
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April 2005 in “Experimental dermatology” Prostaglandin F2alpha and related compounds can increase hair growth and darken hair in mice.
5 citations
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February 2022 in “Stem cell reports” Thymic stromal lymphopoietin (TSLP) promotes hair growth, especially after skin injury.
9 citations
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July 1993 in “The journal of investigative dermatology/Journal of investigative dermatology” Sex hormones and antiandrogens can either stimulate or inhibit human hair follicle cell growth depending on the dose.
1 citations
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June 2013 in “Science-business Exchange” Increasing the levels of a protein called FGF9 can promote hair growth, but humans may not respond the same way due to a lack of certain cells.
January 2010 in “Journal of Yangzhou University” Sulfated fucans promote hair growth in mice by speeding up the growth phase and delaying the rest phase.
August 2018 in “The Molecular Biology Society of Japan”
August 2013 in “Nature Reviews Drug Discovery” A protein called FGF9 helps regenerate hair follicles in mice after skin damage, and increasing FGF9 could potentially help human hair growth.
January 2021 in “Figshare” Melatonin helps Cashmere goat hair follicles grow by affecting stem cell signals and the surrounding microenvironment.
12 citations
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May 2002 in “PubMed” Hair growth is regulated by a combination of hormones, blood vessels, and nerve signals.
29 citations
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March 2015 in “Journal of Investigative Dermatology” Cyclosporine A promotes hair growth and prolongs the active growth phase in human hair follicles, but may work differently than in rodents.