Folicrex may help with hair growth and health but lacks clinical evidence.
Activin A and Follistatin affect how mouse hair follicles grow.
1 citations
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June 2013 in “Science-business Exchange” Increasing the levels of a protein called FGF9 can promote hair growth, but humans may not respond the same way due to a lack of certain cells.
April 2026 in “Brazilian Journal of Hair Health” This narrative review explores the role of perifollicular fibrosis in androgenetic alopecia (AGA), highlighting its impact on hair regrowth and treatment efficacy. The review discusses the pathophysiology involving androgen-driven profibrotic signaling, TGF-β activation, and chronic microinflammation, which contribute to collagen deposition and dermal sheath thickening, creating barriers to follicular regeneration. Conventional treatments like minoxidil and 5-alpha-reductase inhibitors show limited antifibrotic effects in advanced cases. Promising therapeutic strategies include anti-inflammatory approaches, microneedling, platelet-rich plasma, regenerative cell therapies, and targeting TGF-β and CXCL12. However, robust randomized controlled trials are needed to validate these antifibrotic strategies, with future research focusing on combination therapies addressing both androgen signaling and fibrotic pathways.
39 citations
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May 2010 in “Stem Cells” Ephrins slow down skin and hair follicle cell growth.
2 citations
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November 2007 in “Journal of Investigative Dermatology” Fluocinolone acetonide slows down hair follicle stem cells but speeds up skin cell growth in mice.
September 2023 in “Cosmoderma” Early diagnosis and treatment of favus can prevent permanent hair loss.
4 citations
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May 2009 in “Clinical and experimental dermatology” Flexural follicular lichen planus is a rare skin condition affecting body folds.
20 citations
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July 2005 in “Experimental dermatology” The fuzzy gene is crucial for controlling hair growth cycles.
45 citations
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January 2012 in “Experimental Dermatology” Human hair follicles switch between active and resting phases unpredictably.
January 2023 in “Медицинский вестник Северного Кавказа” The patient with Hoffman's folliculitis got better with the right treatment, leading to hair regrowth.
September 2024 in “Journal of the American Academy of Dermatology” Phenoxyethanol in hair growth products may be linked to frontal fibrosing alopecia.
Activin A and follistatin control when ear hair cells form in mice.
11 citations
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January 1988 51 citations
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May 1984 in “Journal of the American Academy of Dermatology” Benign follicular mucinosis involves immune cells attacking hair follicles.
40 citations
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January 2013 in “International journal of trichology” Perifollicular erythema can indicate active frontal fibrosing alopecia.
June 2020 in “Zenodo (CERN European Organization for Nuclear Research)” Controlled microflora in animals delays immune cell maturation and affects immunity.
6 citations
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March 2005 in “Journal of the American Academy of Dermatology” Follicular dystrophy in immunocompromised patients may be linked to medication or viral factors and can improve with treatment changes.
April 2022 in “Jurnal Ilmiah Kesehatan Media Husada” Telogen effluvium is a common, reversible hair loss condition treatable with patient education and sometimes Minoxidil.
September 2017 in “Klìnìčna farmacìâ” The cream with plant substances can stimulate hair follicles.
April 2023 in “The journal of investigative dermatology/Journal of investigative dermatology” Folliculotropic mycosis fungoides has unique molecular features and cell interactions that could guide targeted therapy.
45 citations
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November 2017 in “Biomaterials” Researchers found a new way to create hair-growing structures in the lab that can grow hair when put into mice.
January 1995 in “Revista de arqueología” 1 alpha,25-dihydroxy-vitamin D3 and calcipotriol speed up cell differentiation in hair follicles.
10 citations
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April 2016 in “Research and reports in transdermal drug delivery” Transfollicular drug delivery is promising but needs more research to improve and understand it better.
Keratinocytes grew and migrated into hair follicle areas but disappeared after 15-20 days.
11 citations
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December 1921 in “Archives of dermatology and syphilology” A rare scalp disease causes hair loss, pus-filled nodules, and scarring.
6 citations
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July 2004 in “JDDG Journal der Deutschen Dermatologischen Gesellschaft” Frontal fibrosing alopecia in postmenopausal women can be managed with early treatment using corticosteroids to stop hair loss.
April 2018 in “Journal of Investigative Dermatology” FOL-005, a hair growth promoter, acts locally on mouse skin where injected and could be a promising hair loss treatment.
72 citations
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November 2012 in “PloS one” The protein folliculin, involved in a rare disease, works with another protein to control how cells stick together and their organization, and changes in this interaction can lead to disease symptoms.
March 2003 in “CRC Press eBooks” Telogen effluvium is hair loss caused by many hairs stopping growth suddenly, often due to stress or illness, but sometimes it's normal and not due to disease.