97 citations
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January 2006 in “Dermatology” imTA and pulse therapy are effective for alopecia areata with manageable side effects, but relapse rates need improvement.
6 citations
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August 1996 in “The Journal of Clinical Endocrinology and Metabolism” MK-386 and finasteride together effectively reduce DHT levels, potentially treating acne and male pattern baldness.
3 citations
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August 2019 in “Journal of The American Academy of Dermatology” Clascoterone safely promotes hair growth similar to minoxidil.
June 2013 in “Clinical Neurophysiology” Finasteride improved reflexes and motor activity in rats with liver-related brain issues.
4 citations
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January 2006 in “PubMed” DHT deficiency may disrupt rat epididymis function by affecting estrogen receptors.
111 citations
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August 2002 in “Journal of Medicinal Chemistry” New compounds were made that block an enzyme linked to breast cancer better than existing treatments.
4 citations
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January 1998 in “Heterocycles” Researchers made two new compounds that could be used for medicine.
September 2002 in “Research Repository (Kingston University London)” Mimicking the steroid A-ring may help create effective enzyme inhibitors for prostate disease treatment.
10 citations
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October 2020 in “Microscopy and Microanalysis” Resveratrol helps prevent finasteride-induced damage in male rats, improving reproductive function.
September 2020 in “Oxford University Press eBooks” Unable to provide a summary as the provided text does not contain enough information.
3 citations
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August 2018 in “Therapeutics and Clinical Risk Management” Corticosteroid therapy for alopecia areata can cause severe hip bone damage.
29 citations
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November 1975 in “Clinics in endocrinology and metabolism” Testosterone is made by Leydig cells, is active when not bound to proteins, and works by binding to receptors in muscles and other tissues.
December 2023 in “Journal of ethnopharmacology” Tribuloside can increase skin pigmentation by enhancing melanin production and distribution.
January 1988 in “Toxicological Sciences” 4PeCDF is highly toxic to male rats, causing weight loss, organ damage, and death.
6 citations
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February 2020 in “Journal of Natural Products” A new compound from a sponge strongly inhibits an enzyme linked to male-pattern hair loss without being toxic at low levels.
2 citations
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October 2010 in “BMB Reports” L-threonate may help prevent balding by blocking a key hair loss factor.
204 citations
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May 2014 in “The Journal of Sexual Medicine” Hormone therapy for trans individuals is effective and generally safe in the short term.
24 citations
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May 2015 in “Schizophrenia Research” A drug improved schizophrenia-like symptoms in stressed rats by changing brain steroid levels.
1 citations
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January 1995 in “Journal of Investigative Dermatology” RU58841, a substance from France, can potentially block the effects of hormones that cause hair loss and excessive hair growth, performing better than a similar substance, cyproterone acetate.
9 citations
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August 2012 in “Thermochimica Acta” Finasteride's two forms have different stability based on temperature and pressure.
January 2022 in “Asian journal of Current Research in Clinical Cancer” Some dibenzo compounds might help treat cancer with fewer side effects.
21 citations
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January 2021 in “Therapeutic Advances in Endocrinology and Metabolism” Testosterone may have a dual role in COVID-19, potentially worsening outcomes in men, and testosterone therapy could help some patients, but more research is needed.
December 2022 in “Journal of The European Academy of Dermatology and Venereology” The 7.1% withdrawal rate was in the oral finasteride group, not the topical one.
3 citations
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April 2021 in “Journal of Medicinal Chemistry” Finasteride may affect PNMT, causing side effects.
Flutamide helps with prostate cancer and some skin conditions but can harm the liver.
24 citations
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September 2002 in “Der Urologe” A stronger dual 5α-reductase inhibitor could improve treatment for benign prostatic hyperplasia by further reducing DHT levels.
April 2025 in “The Journal of Urology” Long-term finasteride use may lower prostate cancer risk but increase the need for erectile dysfunction medication.
January 2025 in “International Journal of Pharmacology” Both steroids, especially cyproterone acetate, harm quail's vital organs.
20 citations
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August 1987 in “Journal of steroid biochemistry/Journal of Steroid Biochemistry” Aldactone was more effective in reducing hair growth in women with hirsutism than Diane, despite having less impact on hormone levels.
Finasteride and testosterone are the drugs most linked to male infertility, but many other potential drugs may be under-reported.