Keratinocytes grew and migrated into hair follicle areas but disappeared after 15-20 days.
15 citations
,
April 2014 in “Experimental Dermatology” Scientists developed a system to study human hair growth using skin cells, which could help understand hair development and improve skin substitutes for medical use.
January 1995 in “Skin Cancer” The outer root sheath in hair follicles changes during growth, with different keratinization processes in its layers.
1 citations
,
June 2017 in “PLOS ONE” Host cells are crucial for the maturation of reconstructed hair follicles.
27 citations
,
December 1997 in “Archives of Dermatological Research” Rat dermal papilla cells have unique properties and interact differently with their environment compared to other skin cells.
4 citations
,
June 2007 in “PubMed” Engineered skin with specific cells can effectively repair skin and restore its function.
37 citations
,
January 2022 in “Frontiers in Genetics” Aging reduces dermal sheath cells, affecting youthful skin appearance.
211 citations
,
April 2013 in “Development” More dermal papilla cells in hair follicles lead to larger, healthier hair, while fewer cells cause hair thinning and loss.
September 2021 in “Morphologia” Dermal fibroblasts have at least three distinct types, each with unique roles in skin structure and hair development.
1 citations
,
October 2024 in “European Journal of Histochemistry” Telocytes in silky fowl embryos develop distinct features and connections by the 20th day of incubation.
December 2004 in “Reproduction Fertility and Development” Porcine hair follicles are useful for studying keratinocyte function, with galectin-1 as a potential stem cell marker.
April 2017 in “The journal of investigative dermatology/Journal of investigative dermatology” Human hair follicles can be used to create heart muscle cells.
March 2020 in “Central European Journal of Biology” The study found that stem cells and neutrophils are important for regenerating hair follicle structures in mice.
1 citations
,
February 2016 in “Cell Transplantation” Hair follicles have a more inactive cell cycle than other skin cells, which may help develop targeted therapies for skin diseases and cancer.
16 citations
,
August 2019 in “Cell Proliferation” Keratinocytes help keep hair follicle cells and skin cells separate in 3D cultures, which is important for hair growth research.
1 citations
,
June 2020 in “bioRxiv (Cold Spring Harbor Laboratory)” Fetal skin has unique immune cells different from adult skin.
10 citations
,
April 2013 in “Journal of Investigative Dermatology” Scientists created a model using sheep cells to study hair root formation, which can test how different substances affect hair growth.
Finasteride-loaded microemulsions, made with cinnamon oil, Tween20, propylene glycol, and water, can help maintain stemness of dermal cells, potentially aiding in hair regeneration.
The skin can still regenerate and function well even with fewer fibroblasts.
6 citations
,
February 2014 in “Experimental Dermatology” Hair follicle regeneration is possible but challenging, especially in humans, due to the need for specific cells and a better understanding of how they signal growth.
78 citations
,
August 2002 in “Experimental Dermatology” Researchers developed a quick and easy way to get and grow cells from the base of human hair follicles.
9 citations
,
July 1993 in “The journal of investigative dermatology/Journal of investigative dermatology” Sex hormones and antiandrogens can either stimulate or inhibit human hair follicle cell growth depending on the dose.
22 citations
,
February 2008 in “Biochemical and Biophysical Research Communications” Androgen effects on hair follicles vary by skin area.
28 citations
,
November 2013 in “Cell and Tissue Research” January 2017 in “PRISM (University of Calgary)” Unique genes in hair follicle cells help tissue regeneration.
April 2023 in “Journal of Investigative Dermatology” The research mapped gene activity in developing mouse skin and found key markers for skin cell types and changes from fetal to early postnatal stages.
January 2008 in “Yearbook of Dermatology and Dermatologic Surgery” One type of progenitor cell can maintain normal skin in mice.
2 citations
,
September 2022 in “Organoid” A new method was developed to efficiently grow skin hair follicles from stem cells, potentially aiding alopecia treatment.
19 citations
,
July 1993 in “The journal of investigative dermatology/Journal of investigative dermatology” Dermal-epidermal interactions are crucial for hair growth and maintenance.
April 2023 in “Journal of Investigative Dermatology” Protein analysis shows aging changes in scalp cell types from women.