research HDAC6-dependent deacetylation of NGF dictates its ubiquitination and maintains primordial follicle dormancy
HDAC6 helps keep ovarian follicles dormant, extending female fertility.
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research Advances in mitochondria-centered mechanism behind the roles of androgens and androgen receptor in the regulation of glucose and lipid metabolism
Androgens and androgen receptors are important for metabolic health, affecting how the body uses glucose and fats through mitochondrial function.
research Vpliv prehrane na pojavnost aken
A Western diet may increase acne risk, while a Mediterranean diet and certain supplements can help reduce it.
research Avaliação do impacto da redução significativa de peso pela dieta cetogênica de muito baixa caloria nos parâmetros metabólicos, inflamatórios, hormonais e seminais de homens obesos
A very low-calorie ketogenic diet led to weight loss and improved metabolic and hormonal health in obese men, with better sperm motility.
research 毛乳頭細胞と毛包上皮細胞間の細胞内・細胞外情報伝達
3D-oxy exosomes may significantly boost hair growth, offering new treatment options for hair loss.
research Encapsulación en ciclodextrinas de compuestos con actividad frente a la alopecia androgénica masculina.
Encapsulating hair loss drugs in cyclodextrins improves their solubility and reduces scalp irritation.
research SnapshotDx Quiz: April 2019
Seborrheic dermatitis is influenced by diet, genetics, and psychological factors.
research Perspectives of Alopecia behind the Regulation of Foxn1 Gene Exposes the Human Nude Phenotype
The gene Foxn1 is important for hair growth, and understanding it may lead to new alopecia treatments.
research Alopecia areata susceptibility variant identified by MHC risk haplotype sequencing reproduces symptomatic patched hair loss in mice
A gene variant causes patched hair loss in mice, similar to alopecia areata in humans.
research TLR3 signaling modulates immunomodulatory property of human periodontal ligament stem cells.
TLR3 signaling enhances the immunosuppressive properties of human periodontal ligament stem cells.
research Genetic Defects of Female Sexual Differentiation
Genetic mutations can affect female sexual development, requiring personalized medical care.
research Obesity and peri-implantation endometrium
Obesity negatively affects the endometrium, leading to higher miscarriage risk and impaired cell function.
research Modelling androgen synthesis and action during human sexual differentiation
Male sexual differentiation is regulated independently, while female differentiation occurs in an androgenic environment, affecting conditions like congenital adrenal hyperplasia.
research A Study of the androgen receptor gene polymorphism and the level of expression of the androgen receptor in androgenetic alopecia among Egyptians
The study suggests that a specific gene variation and higher gene activity are linked to increased baldness in Egyptian men.
research First use of thymus transplantation therapy for FOXN1 deficiency (nude/SCID): a report of 2 cases
Thymus transplantation successfully restored immune function in infants with FOXN1 deficiency.
research Biology and Genetics of Hair
The document concludes that understanding the genes and pathways involved in hair growth is crucial for developing treatments for hair diseases.
research Unraveling the Molecular Mechanisms of Hair and Nail Genodermatoses
Genetic discoveries are key for understanding, diagnosing, and treating inherited hair and nail disorders.
research Expanding research and development of novel agents for the treatment and prevention of chemotherapy-induced alopecia
No FDA-approved treatments for chemotherapy-induced hair loss existed in 2006; more research was needed.
research A novel hairless highly immunodeficient mice model optimized for in vivo imaging
The new Hairless R/J mice model improves imaging for tumor monitoring and cancer therapy evaluation.
research All Roads Go to the Nucleus: Integration of Signaling/Transcription Factor-Mediated and Epigenetic Regulatory Mechanisms in the Control of Skin Development and Regeneration
The nucleus is key in controlling skin growth and repair by coordinating signals, gene regulators, and epigenetic changes.
research Aging in hair follicle stem cells and niche microenvironment
Aging in hair follicle stem cells leads to hair graying, thinning, and loss.
research Role of Metformin in Acanthosis Nigricans
Metformin may improve acanthosis nigricans by reducing insulin resistance.
research The role of hair follicles in the percutaneous absorption of caffeine
Hair follicles significantly increase the speed and amount of caffeine absorbed through the skin.
research Cutaneous Scarring: Basic Science, Current Treatments, and Future Directions
New effective scar treatments are urgently needed due to the current options' limited success.
research Action of isotretinoin in acne rosacea and gram-negative folliculitis
Isotretinoin is highly effective in treating severe acne, rosacea, and gram-negative folliculitis.
research What Surgeons Need to Know About Gender Confirmation Surgery When Providing Care for Transgender Individuals
Surgeons must understand the full care process for gender confirmation surgery to help transgender individuals effectively.
research Flares of systemic lupus erythematosus during pregnancy and the puerperium: prevention, diagnosis and management
Pregnancy can increase lupus activity, but careful planning and treatment can improve outcomes.
research Tumour regression predicts higher risk of sentinel node involvement in thin cutaneous melanomas
Shrinking skin cancer increases the chance of cancer in nearby lymph nodes.
research Treatment of Vitiligo With the 308-nm Xenon Chloride Excimer Laser
The 308-nm excimer laser is a promising treatment for vitiligo with varying success and mild side effects.
research Topical minoxidil in alopecia areata
Minoxidil helps hair regrowth in alopecia areata safely.