June 2012 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” Six new risk spots for early hair loss were found, which also link to Parkinson's disease and lower fertility. Two genes, FOXA2 and HDAC4, could be new treatment targets. Hair loss might also be connected to heart disease, metabolic syndrome, and prostate cancer.
15 citations
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November 2020 in “Physiological reports” Sox6 is important in heart and kidney health, affecting diseases like diabetes, heart disease, and high blood pressure.
245 citations
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April 2009 in “Circulation Research” CD133+ cells help heal diabetic ulcers by promoting blood vessel growth and activating Wnt signaling.
11 citations
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April 2022 in “International Journal of Molecular Sciences” Understanding the Wnt/β-catenin pathway and photobiomodulation could improve diabetic wound healing.
55 citations
,
August 2024 in “Heliyon” Stem cell transplantation shows promise for treating diseases but faces challenges like safety, ethics, and cost.
46 citations
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August 2022 in “Animals” miR-144-y and FOXO3 play key roles in skin and feather development in Zhedong White geese.
20 citations
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August 2020 in “Stem Cell Research & Therapy” miR-150 helps blood vessel cells develop and speeds up blood clot healing.
12 citations
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June 2013 in “Gene” Researchers found genes that affect hair growth in Yangtze River Delta white goats.
11 citations
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June 2017 in “Asian-Australasian journal of animal sciences” Fox genes are important for hair growth and development in cashmere goats.
9 citations
,
August 2024 in “Pharmacological Reviews” The intestinal lymphatic system is active and promising for targeted drug delivery and therapies.
1 citations
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September 2023 in “Applied sciences (Basel)” Ishige sinicola extract may help prevent muscle atrophy through its antioxidant and anti-inflammatory effects.
March 2026 in “Journal of Zhejiang University (Medical Sciences)” Angelica sinensis helps repair and regenerate the thymus in mice.
7 citations
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January 2020 in “The journal of investigative dermatology/Journal of investigative dermatology” NIPP1 is important for healthy skin and could help treat skin inflammation.
Qu-shi-yu-fa Decoction may help treat hair loss by promoting hair growth and strengthening hair follicles.
8 citations
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November 2019 in “Clinical Science” High DHA levels delay wound healing and worsen skin repair quality.
April 2010 in “The journal of immunology/The Journal of immunology” FoxN1 gene is crucial for proper thymus structure and normal skin appearance.
35 citations
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June 2012 in “PloS one” Keratin 15 expression in skin cells is regulated by two mechanisms involving PKC/AP-1 and FOXM1.
318 citations
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January 2022 in “Signal Transduction and Targeted Therapy” The Wnt/β-catenin pathway is important for body functions and diseases, and targeting it may treat conditions like cancer, but with safety challenges.
177 citations
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March 2018 in “International Journal of Molecular Sciences” mTOR inhibitors may help treat lung fibrosis.
59 citations
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August 2021 in “Frontiers in Endocrinology” GLP-1 receptor agonists, like Dulaglutide, Liraglutide, and Semaglutide, have potential benefits beyond the pancreas, including neuroprotection, pain suppression, cardiovascular protection, obesity management, and cancer treatment, but there are concerns about pancreatitis and pancreatic cancer risks.
54 citations
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January 2023 in “Signal Transduction and Targeted Therapy” New therapies are being developed that target integrin pathways to treat various diseases.
48 citations
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April 2023 in “Aging Cell” Targeting cellular senescence may improve skin aging and disorders.
41 citations
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June 2024 in “Journal of Cellular and Molecular Medicine” Natural antioxidants may help prevent hair loss by reducing oxidative stress.
21 citations
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July 2018 in “International Journal of Molecular Sciences” Foxn1 is crucial for skin development and healing, and altering its expression may aid regenerative medicine.
19 citations
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July 2019 in “Journal of Endocrinology” GTx-024 and Danazol affect the uterus like DHT, while GTx-007 has little impact.
15 citations
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January 2023 in “Journal of Translational Autoimmunity” Melatonin may help treat skin conditions.
7 citations
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August 2020 in “Genes” Different genes are active in dogs' hair growth and skin, similar to humans, which helps understand dog skin and hair diseases and can relate to human conditions.
6 citations
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August 2022 in “Science immunology” Foxn1 gene regulation is crucial for thymus development but not for hair growth.
6 citations
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February 2021 in “Frontiers in Cell and Developmental Biology” Eating too much or too little vitamin A can cause hair loss.
4 citations
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January 2019 in “Evidence-based Complementary and Alternative Medicine” Yangyin Qingre Huoxue Prescription may help treat atherosclerosis with fewer liver side effects than simvastatin.