research The 5-alpha reductase inhibitor finasteride reduces dyskinesia in a rat model of Parkinson’s disease
Finasteride reduces movement issues in Parkinson's disease rats.
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research News in brief
A new protein linked to Alzheimer's was discovered, and a hair loss treatment showed effectiveness but had some sexual side effects.
research Serotoninergic and melatoninergic systems are fully expressed in human skin
Human skin can make serotonin and melatonin.
research Finasteride toxicity information: “limited”, “poor quality”, “biased”
Finasteride toxicity information is limited, poor quality, and biased.
research 1409 Temporary cell cycle arrest by ALRN-6924: A novel, p53-targeting strategy to protect human scalp hair follicles against cyclophosphamide-induced alopecia
ALRN-6924 can protect hair follicles from chemotherapy damage by temporarily stopping cell division.
research Psoriasiform drug eruption to finasteride: Uncommon side effect of a commonly used drug
Finasteride can cause rare but serious skin rashes.
research Effect of finasteride on adrenal steroidogenesis in men.
Finasteride, when taken daily, lowers dihydrotestosterone levels but doesn't noticeably affect adrenal steroid production, except by blocking the 5 alpha-reductase enzyme.
research Review of Fluconazole Properties and Analytical Methods for Its Determination
The document concludes that validated methods are needed to ensure the quality of fluconazole drugs and that new antifungal medications are necessary due to safety and resistance concerns.
research Biosynthetic studies through feeding experiments in Eclipta prostrata (L.) L. hairy roots
The study found that in Eclipta prostrata roots, coumestans come from acetate and shikimate pathways, and phenylpropanoid is made only through the shikimate pathway.
research Frontal fibrosing alopecia associated with lichen planus pigmentosum
research Abstracts
Mice treatments didn't grow hair, a patient treatment may affect immune response, and people with hair loss often feel anxious or depressed.
research 5mg/day finasteride treatment for normoandrogenic Asian women with female pattern hair loss
Finasteride 5mg/day improves hair loss in normoandrogenic Asian women.
research Finasteride-induced recurrent aphthous ulceration–like lesions: a case report with dechallenge–rechallenge confirmation
Finasteride can cause recurrent mouth ulcers.
research Topical Finasteride: A Comprehensive Review of Androgenetic Alopecia Management for Men and Women
Topical finasteride might be a good alternative for hair loss treatment with fewer side effects, but more research is needed.
research Exploration of the Possible Relationships Between Gut and Hypothalamic Inflammation and Allopregnanolone: Preclinical Findings in a Post-Finasteride Rat Model.
Allopregnanolone may help reduce inflammation and symptoms related to post-finasteride syndrome.
research Metabolite screening of aromatic amine hair dyes usingin vitrohepatic models
The tested hair dye ingredients do not form harmful oxidized metabolites in the liver.
research Steven Kossards postmenopausal frontal fibrosing alopecia (PFFA)--a therapeutic dilemma.
Current treatments for postmenopausal frontal fibrosing alopecia stop hair loss but don't regrow hair.
research Clinical observation of simultaneous continuous infusion of fluorouracil and disodium folinate combined with oxaliplatin for metastatic colorectal cancer
Disodium folinate can safely and effectively replace calcium folinate in colorectal cancer treatment.
research 11β-Hydroxylase inhibitors protect against seizures in mice by increasing endogenous neurosteroid synthesis
11β-Hydroxylase inhibitors help prevent seizures in mice by boosting natural neurosteroid production.
research The increasing incidence of frontal fibrosing alopecia. In search of triggering factors
Various potential triggers may be causing the rise in frontal fibrosing alopecia, and avoiding these could help stop the disease's increase.
research Frontal fibrosing alopecia – review of recent case reports and case series in PubMed
Most patients with frontal fibrosing alopecia are middle-aged women, often have thyroid disease, and some treatments can help stabilize the condition.
research Association between finasteride with subjective memory deficits: a study from the NHANES and FAERS databases
Finasteride use is linked to a higher risk of memory problems.
research Abstract 313: Finasteride Delays Atherosclerosis Progression and Reduces Hepatic Inflammation in Low-density Lipoprotein Receptor-deficient Mice
Finasteride may slow down heart disease by lowering cholesterol and reducing inflammation.
research A 2018 Approach to Combating Methotrexate Toxicity Folic Acid and Beyond.
New strategies like vitamin A and dextromethorphan can help reduce methotrexate side effects and improve patient adherence.
research Urticarial rush due to finasteride
Finasteride can cause skin rash.
research Synthesis, Anticancer and Molecular Docking Studies of 2-(4-chlorophenyl)-5-aryl-1,3,4-Oxadiazole Analogues
The compound 4c showed strong potential as an anticancer agent.
research Synergy of Eflornithine Cream with Laser and Light-Based Systems for Hair Management
Using Eflornithine cream with laser treatments improves facial hair removal.
research Determination of finasteride in human serum by LC-MS/MS
A reliable method was developed to measure finasteride levels in human serum.
research β-Nicotinamide Mononucleotide Promotes Cell Proliferation and Hair Growth by Reducing Oxidative Stress
NMN could potentially treat hair loss by reducing oxidative stress and improving cell health.
research Review of Fluconazole Properties and Analytical Methods for Its Determination
Fluconazole is an effective antifungal medication with potential side effects and lacks official analytical methods for its determination.