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Three specific 4-azasteroid-2-oximes showed strong enzyme inhibition, but less than finasteride.

FA-MNPs effectively targeted and killed cancer cells but didn't overcome drug resistance.

Researchers created a skin patch that delivers two drugs for treating enlarged prostate, which may improve patient use and dosage control.

Trazodone might help reverse post finasteride syndrome.

Liarozole may be more effective than cyproterone acetate for treating advanced prostate cancer, with better PSA response and survival rates, while maintaining quality of life.

Intralesional triamcinolone acetonide helps regrow eyebrows in patients with frontal fibrosing alopecia.

FOL-005 peptide may help treat excessive hair growth safely.

Tamsulosin increases the risk of floppy iris during eye surgery.

Using GnRHa agonists helps diagnose and treat ovarian hyperthecosis when surgery isn't possible.

Finasteride reduces prostate cancer risk but may increase high-grade tumors; new drugs and better diagnosis are in development, but funding and industry commitment are challenges.

Progesterone's seizure-reducing effects are mainly due to allopregnanolone, not progesterone receptors.

PCOS women have more severe metabolic issues and higher androgen levels than hyperandrogenic women without PCOS.

Higher SRD5A2 expression predicts better response to finasteride in treating urinary symptoms.

Alpha-blockers and 5-alpha reductase inhibitors are main treatments for BPH, with new support for phosphodiesterase-5 inhibitors and beta-3 agonists.

A male patient developed frontal fibrosing alopecia after antiandrogen therapy for prostate cancer.

GLP-1 receptor agonists, like Dulaglutide, Liraglutide, and Semaglutide, have potential benefits beyond the pancreas, including neuroprotection, pain suppression, cardiovascular protection, obesity management, and cancer treatment, but there are concerns about pancreatitis and pancreatic cancer risks.

Pramipexole can cause side effects like dizziness, sleepiness, hallucinations, and low blood pressure, and it's important to educate patients and keep doses low.

The model improves understanding of androgen interactions by focusing on signal intensity and system capacity.

The study suggests hormonal factors may play a role in Frontal Fibrosing Alopecia and that treatments like oral antiandrogens and steroids could be beneficial.

Blocking prolactin increases the activity of secondary hair follicles in cashmere goats.

The document confirms the structures of major metabolites of the CRTh2 antagonist Setipiprant and identifies minor metabolites.

Tafluprost could be a potential treatment for hair loss by promoting hair growth phase changes.

5αR inhibitors help slow early prostate cancer cell growth, suggesting combined treatments are needed.

Blocking CRF1 receptors improved male hormone levels and reduced testicular tumor size in men with a specific adrenal condition.

Certain progesterone derivatives can inhibit enzymes and reduce androgenic activity, potentially affecting prostate growth.

Regulatory challenges make developing combination therapies in urology difficult and costly.

5α-reduced neurosteroids may help regulate glial cell differentiation.

The drug BAY 1158061 is safe, well-tolerated, and shows potential for treating diseases related to prolactin.

Allopregnanolone affects fear responses differently in male and female rats, possibly explaining sex differences in anxiety disorders.