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Frontal fibrosing alopecia shows increased inflammation and JAK-STAT pathway activity without reduced hair proteins.

Tofacitinib is a promising treatment for children with rheumatic diseases.

The Notch signaling pathway helps in mouse hair development through a noncanonical mechanism that does not rely on RBPj or transcription.

Fibroblast growth factor receptor signaling controls cell development and repair, and its malfunction can cause disorders and cancer, but it also offers potential for targeted therapies.

Gap junctions help control feather pattern formation by enabling cell communication.

Frizzled 3 and Frizzled 6 together control the orientation of mouse hair follicles.

The protein FLCN is involved in cellular cleanup and is regulated by ULK1.

Blocking the NOTCH pathway can prevent fibrosis in systemic sclerosis.

Collagen XXII is a marker for tissue junctions, aiding in structural integrity and found in muscles, heart, skin, and arthritic joints.

Tcf3 helps cells move and heal wounds by controlling lipocalin 2.

FGF9 controls which receptors it binds to through a process where two FGF9 molecules join, and changes in FGF9 can lead to incorrect receptor activation.

Blocking JAK-STAT signaling can lead to hair growth.

Cirsium japonicum flower extract increases melanin production and could help treat depigmentation conditions.

ACKR2 helps prevent skin scarring and hair loss by controlling inflammation.

Folliculin helps regulate energy and nutrient sensing, impacting Birt–Hogg–Dubé syndrome.

FR-1 reduces skin scarring and promotes healing without harmful effects.

A new test helps find drugs to treat head and neck cancer by targeting c-Rel.

Foxc1 helps keep hair follicle stem cells inactive, preventing hair loss.

Disrupting Notch signaling in blood vessels increases scarring during wound healing in mice.

Fos protein is crucial for cell transition to cornification in keratinized tissues.

Granulocyte colony stimulating factor helps heal wounds without scars.

Desmosomes are crucial for skin and heart development, and JNK may help regulate them.

AP-1 and TGFß work together to drive resistance in basal cell carcinoma, suggesting new treatment options.

Far-infrared radiation improves stem cell growth and movement, helping heart therapy.

CS12192 effectively treats alopecia areata with better safety than current options.

Retinoic acid-binding proteins in skin are regulated by β-catenin and Notch signalling.

2-Methoxyestradiol causes cancer cell death by activating specific pathways, but androgens can block this effect.

GLI2 increases follistatin production in human skin cells.