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GlossaryFractional Lasers

target small skin areas to boost collagen and rejuvenation

Fractional lasers, also known as fractional laser therapy or fractional laser resurfacing, are a type of laser treatment that targets small, precise areas of the skin to promote collagen production and skin rejuvenation. By creating microscopic columns of treated skin surrounded by untreated tissue, these lasers help in faster healing and are commonly used for reducing wrinkles, scars, and pigmentation issues.

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research Follicular unit extraction combined with fractional carbon dioxide laser therapy for post‐traumatic eyebrow scar with defects: A prospective and comparative study

3 citations , August 2024 in “Journal of Cosmetic Dermatology”

Combining laser therapy with hair extraction improves eyebrow scar treatment.

research Enhancing hair growth in male androgenetic alopecia by a combination of fractional CO2 laser therapy and hair growth factors

26 citations , May 2017 in “Lasers in Medical Science”

Laser therapy and hair growth factors significantly improve hair density in male baldness.

research Efficacy and Safety of Ablative Fractional CO ₂ Laser Therapy for Localized Scleroderma: A Comprehensive Bench‐to‐Bedside Approach

January 2025 in “Dermatologic Therapy”

CO₂ laser therapy improves skin and hair growth in localized scleroderma without severe side effects.

Research Progress on Fractional CO2 Laser in Multimodal Therapy

research Research Progress on Fractional CO<sub>2</sub> Laser in Multimodal Therapy

January 2025 in “Advances in Clinical Medicine”

Fractional CO2 laser therapy effectively improves skin conditions and recovery when combined with other treatments.

research Does low-energy fractional carbon dioxide laser therapy improve hair regrowth in female-pattern hair loss?

September 2024 in “Egyptian Journal of Dermatology and Venerology”

Low-energy fractional CO2 laser therapy significantly improves hair regrowth in women with female-pattern hair loss.

research Update dermatologic laser therapy

27 citations , November 2010 in “JDDG Journal der Deutschen Dermatologischen Gesellschaft”

New laser therapies are effective for skin damage, hair removal, and fat reduction.

research Progress of clinical research on fractional laser treatment of androgenetic alopecia: A review article

July 2024 in “Journal of Cosmetic Dermatology”

Fractional laser therapy is a promising, effective, and minimally invasive treatment for hair loss.

research Effect of fractional laser alone or in combination on alopecia areata: A systematic review and meta‐analysis

January 2023 in “Journal of cosmetic dermatology”

Fractional lasers effectively treat alopecia areata, especially when combined with minoxidil or cortisol.

research Fractional Photothermolysis Laser Treatment of Male Pattern Hair Loss

50 citations , December 2010 in “Dermatologic Surgery”

Laser treatment can stimulate hair growth for male pattern hair loss.

research Evaluation of the effectiveness of fractional lasers in the treatment of androgenetic alopecia: a literature review

June 2025 in “Medical alphabet”

Fractional lasers, combined with topical therapy, are a promising and safe treatment for hair loss.

The Role of Fractional Laser-Assisted Drug Delivery in Enhancing the Efficacy of Topical Bimatoprost Solution in the Treatment of Alopecia Areata: An Intra-Patient Comparative Randomized Clinical Trial

research The role of fractional laser‐assisted drug delivery in enhancing the efficacy of topical bimatoprost solution in the treatment of alopecia areata: An intra‐patient comparative randomized clinical trial

February 2024 in “Journal of Cosmetic Dermatology”

Using a laser with bimatoprost solution works better for hair regrowth in alopecia areata than bimatoprost alone.

research 1398 Platelet-rich plasma and laser combination therapy in dermatology: A systematic review

April 2023 in “Journal of Investigative Dermatology”

Combining platelet-rich plasma with laser therapy improves treatment for vitiligo, skin rejuvenation, and acne scars, but more research is needed.

research The Effect of Conditioned Media From Human Adipocyte-Derived Mesenchymal Stem Cells on Androgenetic Alopecia After Nonablative Fractional Laser Treatment

10 citations , August 2020 in “Dermatologic Surgery”

Conditioned media from stem cells improves hair growth after laser treatment for hair loss.

research Effects of CO2 fractional laser on hair growth in C57BL/6 mice and potential underlying mechanisms

3 citations , March 2019 in “Chinese Medical Journal”

CO2 fractional laser therapy may help regrow hair without scarring by affecting certain inflammatory and growth-related molecules.

research Effectiveness and safety of the ablative fractional 2940-nm Er: YAG laser for the treatment of androgenetic alopecia

May 2024 in “Lasers in medical science”

The 2940-nm Er: YAG laser combined with medication is a safe and better treatment for male hair loss than medication alone.

research Non-ablative Fractional Laser as an Emerging Treatment for Alopecia Areata

January 2019 in “Clinical Dermatology Open Access Journal”

Combining corticosteroids and non-ablative fractional laser therapy may effectively treat extensive alopecia areata.

research Laser-assisted Hair Regrowth

5 citations , April 2019 in “Plastic and reconstructive surgery. Global open”

Fractional lasers could help hair regrowth in androgenic alopecia, but more research is needed to confirm their effectiveness and safety.

research Lasers Uses in the Treatment of Alopecia Areata: Review Article

1 citations , April 2022 in “The Egyptian Journal of Hospital Medicine ”

Fractional laser therapy may help regrow hair in alopecia areata.

research Lasers for treatment of androgenetic alopecia: an in-depth analysis

February 2025 in “Lasers in Medical Science”

Laser therapy shows promise for hair loss but lacks strong evidence due to limited studies.

research Laser therapies in androgenetic alopecia: Review and clinical experiences

January 2025 in “Journal of Cutaneous and Aesthetic Surgery”

Low-level laser therapy effectively improves hair growth in androgenetic alopecia with minimal side effects.

research Carbon‐dioxide laser‐associated PDT treatment of folliculitis decalvans

1 citations , March 2024 in “International Journal of Dermatology”

CO2 laser-associated PDT effectively treated therapy-resistant folliculitis decalvans.

research Fractional CO2 laser vs Intralesional Corticosteroids in Alopecia Areata: A comparative study of Efficacy, Safety and Predictive factors

December 2025 in “Eurasian Journal of Scientific and Multidisciplinary Research”

Fractional CO2 laser therapy is more effective and safer than corticosteroid injections for treating alopecia areata.

research Lasers in the management of alopecia: a review of established therapies and advances in treatment

April 2024 in “Lasers in medical science”

Lasers and light therapies are effective in promoting hair regrowth for different types of hair loss.

research Symposium 6-4 (SYP 6-4) : Recent progress in the treatment of male pattern hair loss: Lasers and devices

January 2014 in “프로그램북(구 초록집)”

Laser and light treatments show promise for hair growth but need more research.

research Functional hair follicle regeneration: an updated review

42 citations , February 2021 in “Signal Transduction and Targeted Therapy”

Hair follicle regeneration possible, more research needed.

research A Meta-analysis of the Evidence for Assisted Therapy with Platelet-Rich Plasma for Atrophic Acne Scars

16 citations , September 2019 in “Aesthetic Plastic Surgery”

Platelet-rich plasma therapy helps improve atrophic acne scars.

research Laser and Light-Based Therapies in the Treatment of Hair Loss

1 citations , September 2019

Laser and light therapies can help regrow hair but need more research for best results.

research Perifollicular Elastolysis: A Systematic Review of Clinical Characteristics, Histopathology, and Therapeutic Outcomes

February 2026 in “Cosmetics”

Perifollicular elastolysis is poorly understood, with limited treatment options and inconsistent results.

research Achieving Sustained Hair Repigmentation in Poliosis Circumscripta: Retreatment Outcomes Using Exosomes and Fractional Picosecond Laser

1 citations , March 2025 in “Journal of Cosmetic Dermatology”

Exosomes and laser therapy can help regrow and repigment hair.

Enhancing Hair Regrowth in Pediatric Morphea En Coup De Sabre by Fractional CO2 Laser-Assisted Exosome Delivery

research Enhancing Hair Regrowth in Pediatric Morphea en Coup de Sabre by Fractional CO₂ Laser‐Assisted Exosome Delivery

June 2025 in “Journal of Cosmetic Dermatology”

Exosome therapy with laser treatment helped hair regrowth in a child with a rare skin condition.