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270-300 / 1000+ resultsresearch Active mitochondria in healthy spiny mouse fibroblasts resemble megamitochondria and remain resilient across lifespan
Spiny mice have resilient, large mitochondria that help them regenerate tissue.
research Age‐associated decrease in GDNF and its cognate receptor GFR α‐1 protein expression in human skin
Human skin has less GDNF and its receptor with age.
research Preventing and modifying the aging process.
research Senile Changes of Dog Skin
Old dogs' skin thins, loses hair, and may darken, but doesn't show some human aging signs.
research Characteristic features of ageing in Korean women’s hair and scalp
Korean women's hair thins, weakens, and greys with age, with mineral and sterol changes.
research 685 Modelling intrinsic and extrinsic cellular senescence in vitro with complex bioengineered human skin constructs
Bioengineered skin models aging well, useful for studying aging and testing treatments.
research Association of Risk Factors with Female Pattern Hair Loss
Older age, family history, and low iron levels increase the risk of female hair loss.
research Hair follicle aging is driven by transepidermal elimination of stem cells via COL17A1 proteolysis
Hair loss and aging are caused by the breakdown of a key protein in hair stem cells.
research Senescence-induced reparative fibroblasts enable scarless wound healing in aged murine skin.
Older mice heal wounds without scars due to special fibroblasts.
research A clinical study of Geriatric dermatoses at Tertiary care center in South India
Elderly in South India commonly suffer from skin issues like wrinkles, dryness, and infections, needing better skin care education.
research Clinical Analysis of SLE in the Elderly for 33 Cases
Elderly SLE patients show fewer typical symptoms and more hormonal side effects.
research A clinicoepidemiological study of geriatric dermatoses
Older adults commonly experience skin diseases.
research Tissue regenerative delays and synthetic lethality in adult mice after combined deletion of Atr and Trp53
Removing both Atr and Trp53 genes in adult mice causes severe tissue damage and death due to DNA damage.
research Quantifying effects of aging across structures of the mouse auditory system, with in-vitro brain slice preparations
Chronological age affects the mouse auditory cortex more than hearing loss, and the brain may be less sensitive to mitochondrial dysfunction.
research Assessment of Anemia Symptoms in People with Normal Hemoglobin and Low Ferritin
People with normal hemoglobin but low ferritin experience more fatigue and certain symptoms like restless leg syndrome and dizziness.
research Platelet Immune Interactions, Lifespan, and Senescence
Platelets play a key role in the immune system and their lifespan and aging are important for developing new treatments.
research AB0698 SYSTEMIC LUPUS ERYTHEMATOSUS OVER 80 YEARS OF AGE: A RETROSPECTIVE COHORT OF VERY LATE-ONSET IN A THIRD LEVEL HOSPITAL
Older men with late-onset lupus have a higher mortality rate than women.
research Protein-Losing Enteropathy, Anasarca and Dermatological Manifestations on People of Advanced Age: Don't Overlook the Diagnostic Hypothesis of a Cronkhite Canada Syndrome
Early diagnosis and prednisone treatment can improve outcomes in Cronkhite-Canada syndrome.
research Myotonic Dystrophy—A Progeroid Disease?
Myotonic dystrophy may be classified as a segmental progeroid disorder.
research Lifestyle and Physiological Factors Associated with Facial Wrinkling in Men and Women
Age, smoking, and lower BMI increase facial wrinkles; men wrinkle more than women, except in old age; pale skin and certain hormonal factors can protect against wrinkles.
research Cisd2 deficiency impairs neutrophil function by regulating calcium homeostasis via Calnexin and SERCA
Lack of Cisd2 disrupts calcium balance in cells, leading to poorly functioning neutrophils.
research Hair Graying as an Evolutionary Checkpoint against Malignancy: a Stem Cell Perspective
research Role of Vitamins and Nutrition in Old Age as Immune Modulator with Future Prospective
Proper nutrition and vitamins can boost the immune system and overall health in older adults.
research Stable analytic extrapolations in the theory of strong interactions
Oxidative stress causes hair graying by damaging hair follicle melanocytes more than skin melanocytes.
research Cellular senescence in tissue repair: every cloud has a silver lining
Cell aging can be both good and bad for tissue repair.
research The Pathobiology of Skin Aging
Skin aging is a complex process influenced by various factors, leading to wrinkles and sagging, and should be considered a disease due to its health impacts.
research Acquired loss of hair pigment associated with a flexural dermatosis
research Ocular manifestation in progeria: A case report
A boy with progeria had eye problems and signs of aging like hair loss and skin wrinkling.
research Quantitative morphometric analysis of intrinsic and extrinsic skin ageing in individuals with Fitzpatrick skin types II–III
Skin thickness decreases and structural changes occur with both ageing and sun exposure in certain skin types.