research 559 Induction of tissue-specific premature stem cell aging promotes senescence-like phenotypes in remote multiple organs
Aging in one type of stem cell can cause aging-like changes in various organs.
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research Skin fragility, diffuse ecchymosis and blisters on a yellowish waxy base
A woman's skin symptoms led to a diagnosis of systemic AL amyloidosis, but she died from sepsis shortly after.
research Tricotiodistrofia. Reporte de un caso
A 2-year-old boy was diagnosed with a rare genetic condition causing fragile hair, intellectual issues, and short stature.
research Quantifying effects of aging across structures of the mouse auditory system, with in-vitro brain slice preparations
Chronological age affects the mouse auditory cortex more than hearing loss, and the brain may be less sensitive to mitochondrial dysfunction.
research 1431 Skin aging and hair follicle stem cell dysfunction caused by T cells with defective mitochondrial metabolism
Defective T cell metabolism can cause early skin aging and poor hair follicle stem cell function.
research Tissue regenerative delays and synthetic lethality in adult mice after combined deletion of Atr and Trp53
Removing both Atr and Trp53 genes in adult mice causes severe tissue damage and death due to DNA damage.
research Pseudo "fringe sign" in frontal fibrosing alopecia
Frontal fibrosing alopecia can mimic traction alopecia but has distinct features like facial papules and eyebrow thinning.
research Case 21-2012
The patient was diagnosed with anorexia nervosa and severe malnutrition, requiring urgent refeeding and monitoring.
research Pseudoxanthoma-like late-onset focal dermal elastosis
A woman had a skin condition with increased normal elastic fibers, not related to other known disorders, likely due to aging.
research A clinical study spectrum of various cutaneous manifestation in geriatric age group in rural patient
Elderly in rural areas have many skin issues needing targeted healthcare.
research Association of Risk Factors with Female Pattern Hair Loss
Older age, family history, and low iron levels increase the risk of female hair loss.
research END OF LIFE CARE IN INPATIENT PSYCHIATRY: A CASE STUDY ON END-STAGE ALZHEIMER'S DISEASE
The case shows the need for psychiatrists to manage end-of-life care for dementia patients, including respecting patients' wishes and using hospice services.
research Embryonic NIPP1 depletion in keratinocytes triggers a cell-cycle arrest and premature senescence in adult mice
Deleting NIPP1 in mouse skin cells causes early aging and chronic skin issues.
research Transient mitochondrial DNA double strand breaks in mice cause accelerated aging phenotypes in a ROS-dependent but p53/p21-independent manner
Damaging mitochondrial DNA in mice speeds up aging due to increased reactive oxygen species, not through the p53/p21 pathway.
research Sparse Hair on the Scalp
A 5-year-old girl has sparse, dry, and brittle hair but is otherwise healthy.
research The High Prevalence of Skin Diseases in Adults Aged 70 and Older
Most adults over 70 have skin diseases needing treatment, with men more affected than women.
research 1348 Changes in the aging dermal hair follicle environment in female scalp
Aging causes changes in scalp cells that can negatively affect hair health.
research Health Issues Unique to the Aging Man
Aging men face unique health issues like erectile dysfunction, prostate problems, and baldness.
research Lower Urinary Tract Symptoms in the Elderly Male: Choosing Wisely
research AB0698 SYSTEMIC LUPUS ERYTHEMATOSUS OVER 80 YEARS OF AGE: A RETROSPECTIVE COHORT OF VERY LATE-ONSET IN A THIRD LEVEL HOSPITAL
Older men with late-onset lupus have a higher mortality rate than women.
research Erosive Pustular Dermatosis: A Manifestation of Immunosenescence A Report of 8 Cases
Erosive pustular dermatosis in elderly people may be linked to aging immune systems and skin damage.
research Keratin 17 null mice exhibit age- and strain-dependent alopecia
Keratin 17 is crucial for early hair strength and cell survival.
research Raynaud Phenomenon-Reply
Doctors disagree on whether Raynaud phenomenon often leads to serious diseases, but agree that patients should be monitored for possible progression while being reassured. Rapid weight loss may cause hair loss.
research Congenital and Hereditary Skin Diseases
Bovines can have rare inherited skin diseases with specific symptoms like hair loss, fragile skin, and abnormal porphyrin buildup.
research Cellular senescence in tissue repair: every cloud has a silver lining
Cell aging can be both good and bad for tissue repair.
research Caracterización de signos cutáneos y sus anexos, en niños menores de 5 años con desnutrición severa
Severe malnutrition in young children causes various skin and nail issues, mainly pigmentation changes and extreme thinness.
research Frontal Fibrosing Alopecia. An Example of Disrupted Aryl Hydrocarbon Receptor-Mediated Immunological Homeostasis in the Skin?
Excessive sun protection might contribute to frontal fibrosing alopecia.
research Quantitative morphometric analysis of intrinsic and extrinsic skin ageing in individuals with Fitzpatrick skin types II–III
Skin thickness decreases and structural changes occur with both ageing and sun exposure in certain skin types.
research Do Changes in Chromosomes Cause Aging?
Chromosomal changes, including those in the WRN gene and rDNA, may significantly contribute to aging.
research A clinical study of Geriatric dermatoses at Tertiary care center in South India
Elderly in South India commonly suffer from skin issues like wrinkles, dryness, and infections, needing better skin care education.