research Cachexia and graft-vs.-host-disease-type skin changes in keratin promoter-driven TNF alpha transgenic mice.
TNF alpha in skin cells causes weight loss, hair and fat issues, and skin inflammation in mice.
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research Convergent Decay of Skin-specific Gene Modules in Pangolins
Pangolins have lost some skin-related genes, but kept others, showing complex skin evolution.
research Dermatologic Diseases
The document concludes that early diagnosis and treatment are crucial for managing skin diseases in ferrets.
research Never too old to regenerate? Wound induced hair follicle neogenesis after secondary intention healing in a geriatric patient
An 80-year-old patient grew new hair on a wound, showing that elderly people can still regenerate hair.
research Deletion of adipocyte Sine Oculis Homeobox Homolog 1 prevents lipolysis and attenuates skin fibrosis
Removing SIX1 in fat cells reduces skin fibrosis.
research A Unique Acquired Athletic Dermatologic Condition in a Half Marathon Participant: An Autobiographical Case Report of Sports-Associated Clothing Related Axillary Tangled Clumped Hairs (SCRATCH)
A runner developed tangled armpit hairs from shirt friction, preventable by shaving or wearing smooth shirts.
research Somatic mutations distinguish melanocyte subpopulations in human skin
Hair follicles protect melanocytes from sun damage, helping them replenish skin.
research Hypersensitivity Diseases
The document concludes that various hypersensitivity diseases in horses can be diagnosed and treated with methods like immunotherapy and medication, and early aggressive treatment is crucial for severe diseases like equine cutaneous pythiosis.
research Literature Reviews
Multi-pass laser skin treatments improved healing, reduced pain, and had no major complications.
research Head and Neck Reconstruction
The document concludes that individualized reconstruction plans are essential for improving function and appearance after head and neck burns.
research Thy1 marks a distinct population of slow-cycling stem cells in the mouse epidermis
A specific group of slow-growing stem cells marked by Thy1 is crucial for skin maintenance and healing in mice.
research 9 Role of 5α-reductase in health and disease
5α-reductase is essential for male sexual development and its inhibitors have potential in treating various conditions related to hormone action.
research Transcriptomics analysis reveals molecular alterations underpinning spaceflight dermatology
Spaceflight can harm skin health by altering gene expression, affecting DNA, mitochondria, and skin barriers.
research Alopecia.
The document concludes that correct diagnosis of alopecia types is crucial, scalp biopsies are important, and more research is needed.
research Long-term satisfaction and tolerability with low-dose flutamide: a 20-year surveillance study on 120 hyperandrogenic women
Low-dose flutamide improved hirsutism and satisfaction in women but had common side effects, causing some to stop treatment.
research Methods for quantifying intrafollicular drug delivery: a critical appraisal
The document concludes that there is no agreed-upon best method for measuring drug delivery within hair follicles and more research is needed to validate current techniques.
research Anticytokine therapy, particularly anti-IFN-γ, in Th1-mediated autoimmune diseases
Blocking interferon-gamma might help treat various autoimmune diseases.
research Breaking the cycle of hair breakage: pearls for the management of acquired trichorrhexis nodosa
Proper hair care can prevent and stop hair breakage in people with acquired trichorrhexis nodosa.
research Encephalocraniocutaneous lipomatosis: congenital alopecia treatment in a rare neurocutaneous syndrome
A girl with a rare syndrome had successful hair loss treatment with no relapse after 4 years.
research Exosomes for repair, regeneration and rejuvenation
Exosomes could potentially enhance tissue repair and regeneration with lower rejection risk and easier production than live cell therapies.
research Mesotherapy: myth and reality
Mesotherapy lacks strong evidence for effectiveness and safety, and its ingredients are not FDA-approved for subcutaneous use.
research Short-Chain Fatty Acids from Cutibacterium acnes Activate Both a Canonical and Epigenetic Inflammatory Response in Human Sebocytes
Short-chain fatty acids from *Cutibacterium acnes* cause skin inflammation, contributing to acne.
research ATP-dependent chromatin remodeling during mammalian development
ATP-dependent chromatin-remodeling complexes are crucial for gene regulation, cell differentiation, and organ development in mammals.
research Signaling in the stem cell niche: regulating cell fate, function and plasticity
The niche environment controls stem cell behavior and plasticity, which is important for tissue health and repair.
research Diffuse hair loss: Its triggers and management
To manage diffuse hair loss, identify the cause, improve nutrition, remove triggers, and use specific treatments like minoxidil or finasteride.
research Applications of Engineered Skin Tissue for Cosmetic Component and Toxicology Detection
Engineered skin tissue is a promising tool for safer cosmetic testing.
research Advances in Bioprinting to Model Immune‐Mediated Skin Diseases
Bioprinting is improving skin models for better testing of skin diseases without using animals.
research Non-invasive skin measurement methods and diagnostics for vitiligo: a systematic review
Reliable, non-invasive tools are needed for better vitiligo diagnosis.
research A systematic review of dermatologic manifestations among adult patients with COVID‐19 diagnosis
COVID-19 patients often have skin issues like chilblain-like lesions and rashes, which can help in early diagnosis and sometimes indicate severe illness.
research Targeting the Complexity of In Vitro Skin Models: A Review of Cutting-Edge Developments
In vitro skin models are improving but still need more innovation to fully replicate human skin.