305 citations
,
March 2018 in “International journal of molecular sciences” The document concludes that the understanding of scar formation is incomplete and current prevention and treatment for hypertrophic scars and keloids are not fully effective.
47 citations
,
January 2021 in “Fertility and Sterility” COVID-19 might affect male fertility, but more research is needed to understand the full impact.
40 citations
,
January 2010 in “Indian Journal of Dermatology, Venereology and Leprology” Certain diets can affect skin conditions, but more research is needed to understand these relationships fully.
39 citations
,
May 2011 in “Human Immunology” Genetics play a role in acne, but how exactly they contribute is not fully understood.
32 citations
,
October 2015 in “Frontiers in Cellular Neuroscience” DHT is needed for long-term depression, while E2 is needed for full long-term potentiation in male rat brains.
27 citations
,
January 1984 in “Pharmacology & Therapeutics” Antiandrogens have important biological effects, but more research is needed to understand them fully and compare their effectiveness and side effects to other treatments.
21 citations
,
April 2025 in “MedComm” Alopecia areata causes unpredictable hair loss, and more research is needed to fully understand and treat it effectively.
15 citations
,
May 2014 in “Journal of Biological Chemistry” A chimeric keratin partially improved skin structure in mice lacking keratin 5, but didn't fully restore normal skin.
13 citations
,
April 2019 in “Actas Dermo-Sifiliográficas” Vitamin D is important for skin health, but more research is needed to understand its full effects and treatment potential.
13 citations
,
January 2019 in “Endocrine journal” Dihydrotestosterone treatment can help penis growth in boys with 5α-reductase deficiency but doesn't fully normalize size after puberty.
13 citations
,
January 2015 in “Stem cells international” Mesenchymal Stem Cells (MSCs) are promising for multiple therapies, but more research is needed to fully understand and optimize their use.
11 citations
,
November 2022 in “Journal of Endocrinological Investigation” Hormonal treatments can change hair and skin in transgender people, but may not fully achieve desired results.
10 citations
,
March 1992 in “European Archives of Psychiatry and Clinical Neuroscience” Hair loss from mood stabilizers can grow back, but the reasons why are not fully understood.
2 citations
,
October 2022 in “International journal of Ayurvedic medicine” Licorice has many traditional health benefits, but more research is needed to fully support these claims.
1 citations
,
January 2024 in “Skin research and technology” Deoxycholic acid is FDA-approved for reducing submental fat, but its mechanisms are not fully understood.
1 citations
,
January 2023 in “Przegla̧d dermatologiczny” Zinc may be linked to vitiligo development and severity, but its role is not fully understood and zinc supplementation benefits are unclear.
1 citations
,
January 2018 in “Elsevier eBooks” The skin's dermal layer contains true stem cells with diverse functions and interactions that need more research to fully understand.
PCOS has a strong genetic basis, but more research is needed to fully understand it.
April 2026 in “Frontiers in Medicine” Syphilis can cause hair loss even without penetrative sex, but treatment can fully restore hair.
April 2026 in “Zenodo (CERN European Organization for Nuclear Research)” Hibiscus rosa-sinensis has many health benefits, but more research is needed to fully understand its effects.
December 2025 in “Skin Appendage Disorders” Scalp apocrine glands may help remove waste and balance electrolytes, but their role is not fully understood.
Azelaic acid helps with skin pigmentation issues, but its full effects are not completely understood.
July 2025 in “Buletin Veteriner Udayana” The dog's skin condition improved with treatment, but full recovery wasn't achieved, and environmental cleaning is advised to prevent re-infection.
March 2025 in “International Journal of Trichology” Gloriosa superba poisoning can cause sudden hair loss, but hair usually regrows fully.
February 2025 in “The Indian Journal of Animal Sciences” Sarcoptes scabiei caused mange in Goa goats, but they fully recovered with treatment.
April 2024 in “Clinical, cosmetic and investigational dermatology” Saudi dermatologists' understanding and use of low-dose oral Minoxidil for hair loss may not be fully represented due to a small survey sample and language barriers.
March 2024 in “Bioimpacts” 400 nm particles penetrate hair follicles best, but mouse models aren't fully reliable for human studies.
September 2023 in “Asian journal of beauty & cosmetology” Lipids are important for healthy hair, but their exact role is not fully understood and needs more research.
July 2023 in “Skin health and disease” Most UK survey participants had negative side effects from botulinum toxin injections, with many not fully recovering physically, emotionally, or financially.
July 2023 in “Zenodo (CERN European Organization for Nuclear Research)” Ketoconazole effectively treated a scalp infection in a 6-year-old boy, leading to full recovery.