research A role for the Tgf-β/Bmp co-receptor Endoglin in the molecular oscillator that regulates the hair follicle cycle
Endoglin is crucial for proper hair growth cycles and stem cell activation in mice.
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240-270 / 1000+ results research EMATOPOIESIS REVOLVES AROUND THE PRIMORDIALEVOLUTIONAL RHYTHM OF INNATE IMMUNITY AND PURINERGIC SIGNALING – A JOURNEY TO THE DEVELOPMENTAL ROOTS
Ancient immune and signaling pathways still regulate blood cell development.
research Cutaneous wound healing: recruiting developmental pathways for regeneration
Understanding developmental pathways can improve wound healing treatments.
research Molecular Genetic Characteristics of the Hoxc13 Gene and Association Analysis of Wool Traits
Hoxc13 gene affects wool length in Gansu alpine fine-wool sheep.
research Analysis of Sonic Hedgehog signalling pathway gene expression in Basal Cell Carcinoma and in GLII induced systems
GLI and EGF signalling affect Basal Cell Carcinoma development and could be therapeutic targets.
research Tuning Wnt Signals for More or Fewer Hairs
Changing Wnt signaling can lead to more or less hair growth and might help treat hair loss and skin conditions.
research Defining BMP functions in the hair follicle by conditional ablation of BMP receptor IA
BMP receptor IA is essential for proper hair cell differentiation in mice.
research Hordenine Activated Dermal Papilla Cells and Promoted Hair Regrowth by Activating Wnt Signaling Pathway
Hordenine may help hair grow by activating a specific cell growth pathway.
research ISID1448 – Ligand-dependent Wnt signaling attenuates mechanotransduction and protects against wound occlusion-mediated abolishment of hair follicle regeneration
research Study of gene expression alteration in male androgenetic alopecia: evidence of predominant molecular signalling pathways
Hair loss involves immune responses, inflammation, and disrupted signaling pathways.
research LncRNA RP11-818O24.3 promotes hair-follicle recovery via FGF2-PI3K/Akt signal pathway
research Cutaneous transcriptome analysis in NIH hairless mice
Key genes linked to hair growth and cancer were identified in hairless mice.
research Read-Through for Nonsense Mutations in Type XVII Collagen‒Deficient Junctional Epidermolysis Bullosa
A new therapy for a skin blistering condition has not been developed yet.
research 1313 Fzd2 controls multiple aspects of epidermal development through distinct signaling mechanisms
Fzd2 is important for skin and hair development through various signaling ways.
research AP-1 and TGFß cooperativity drives non-canonical Hedgehog signaling in resistant basal cell carcinoma
AP-1 and TGFß work together to drive resistance in basal cell carcinoma, suggesting new treatment options.
research TBG096 stimulates hair regeneration through IGF-1R-mediated angiogenesis
research iTRAQ-Based Quantitative Proteomic Comparison of Early- and Late-Passage Human Dermal Papilla Cell Secretome in Relation to Inducing Hair Follicle Regeneration
Early-stage skin cells help regenerate hair follicles, with proteins SDF1, MMP3, biglycan, and LTBP1 playing key roles.
research The inconsistent regulation of HOXC13 on different keratins and the regulation mechanism on HOXC13 in cashmere goat (Capra hircus)
The HOXC13 gene affects different hair proteins in cashmere goats in varied ways and is controlled by a feedback loop and other factors.
research Decision letter: Deletion of the MAD2L1 spindle assembly checkpoint gene is tolerated in mouse models of acute T-cell lymphoma and hepatocellular carcinoma
Deleting the MAD2L1 gene in mice led to rapid tumor growth despite chromosomal instability.
research Tgm2/Gh, Gbx1 and TGF-beta are involved in retinoic acid-induced transdifferentiation from epidermis to mucosal epithelium
Retinoic acid changes skin cells to mucosal cells with goblet cells, needing TG2/Gh, Gbx1, and TGF-beta.
research Mechanism of Targeting the Hedgehog Signaling Pathway against Chemotherapeutic Resistance in Multiple Myeloma
Blocking the Hedgehog pathway may help overcome drug resistance in multiple myeloma.
research TLR9 activation in large wound induces tissue repair and hair follicle regeneration via γδT cells
Activating TLR9 helps heal wounds and regrow hair by using specific immune cells.
research 1351 Investigation of the molecular identity of the junctional zone in human
GATA6 is important for maintaining and differentiating cells in a key area of human skin.
research A role for the Tgf-β/Bmp co-receptor Endoglin in the molecular oscillator that regulates the hair follicle cycle
Endoglin is important for proper hair growth cycles and stem cell activation in hair follicles.
research 1390 Active hair growth is fuelled by conveyor-belt like differentiation of germinative layer cells
Hair growth is driven by cells that move and change like a conveyor belt.
research Hair-cycle dependent differential expression of ADAM 10 and ADAM 12
ADAM 10 and ADAM 12 proteins are involved in different stages of hair growth and could be targets for treating hair disorders.
research Supplemental Information: Androgenic Alopecia – Crosstalk between Cell Signal Transduction Pathways
research Autotaxin–lysophosphatidic acid– LPA 3 signaling at the embryo‐epithelial boundary controls decidualization pathways
LPA3 signaling in the uterus is crucial for placental formation and fetal development.
research Low‐level laser activates Wnt/β‐catenin signaling pathway‐promoting hair follicle stem cell regeneration and wound healing: Upregulate the expression of key downstream gene Lef 1
Low-level laser therapy can boost hair growth and speed up wound healing.
research Co-opting Developmental Signaling Pathways to Promote Wound Healing
Using developmental signaling pathways could improve adult wound healing by mimicking scarless embryonic healing.