717 citations
,
June 2010 in “Nature” Alopecia areata involves both innate and adaptive immunity, with specific genes linked to the disease.
37 citations
,
December 2019 in “Giornale italiano di dermatologia e venereologia” The Italian guidelines offer advice for diagnosing and treating alopecia areata based on expert opinion and limited clinical trial evidence.
August 2014 in “Journal of clinical & experimental dermatology research” Platelet-released growth factors can treat hair loss by activating hair follicle stem cells, blocking certain pathways, and controlling inflammation and fibrosis.
18 citations
,
February 2014 in “PubMed” Androgenetic alopecia is a common hair loss condition caused by testosterone effects on hair follicles, leading to thinner, shorter, and less pigmented hair, diagnosed using scalp dermoscopy and treated with topical minoxidil, antiandrogen agents, and 5-alpha reductase inhibitors.
Transglutaminases help form strong hair by linking proteins, and can potentially alter hair properties.
November 2024 in “Journal of Investigative Dermatology” The research aims to better understand hair follicle regulation and find new treatments for hair loss.
105 citations
,
February 1996 in “Journal of biological chemistry/The Journal of biological chemistry” The TGM3 gene's promoter region is key for skin and hair cell function and may aid gene therapy.
July 2025 in “Journal of Education Health and Sport” Androgenetic alopecia may indicate higher risk for certain diseases and mental health issues.
November 2021 in “CRC Press eBooks” Female androgenic alopecia causes hair thinning in women, especially after menopause, and affects their mental well-being.
New drugs, baricitinib and ritlecitinib, are effective for severe alopecia areata.
8 citations
,
January 2015 in “Genetics and Molecular Research” Certain gene variations increase the risk of alopecia areata in Koreans.
August 2024 in “British Journal of Dermatology” Rezpegaldesleukin shows promise for treating severe alopecia areata.
June 2023 in “Clinica Chimica Acta” Finasteride and dutasteride effectively reduce DHT in hair, which may help evaluate their treatment success for hair loss.
578 citations
,
April 1993 in “Cell” TGFα gene mutation in mice causes abnormal skin, wavy hair, curly whiskers, and sometimes eye inflammation.
45 citations
,
July 2009 in “Journal of human genetics” A gene variation is linked to hair thickness in Asians.
October 2025 in “Animal Bioscience” Key genes linked to important traits in Chinese sheep and goats have been identified, but challenges remain in breeding improvements.
8 citations
,
November 2019 in “Dermatologic Clinics” AGA treatments like minoxidil and LLLLT are safe and effective for gender minority patients.
31 citations
,
August 2022 in “Frontiers in Oncology” Photobiomodulation therapy helps manage cancer treatment side effects but needs more research for optimization.
21 citations
,
September 2016 in “Breast” Cooler scalp temperatures during chemotherapy may prevent hair loss.
1 citations
,
September 2001 in “PubMed” Acitretin treats severe skin conditions but requires careful monitoring due to serious side effects.
November 2021 in “OPAL (Open@LaTrobe) (La Trobe University)” Melatonin may treat rosacea and Alzheimer's by reducing inflammation and affecting blood vessel growth.
July 2025 in “Skin Research and Technology” Hsa-miR-193a-5p is important in alopecia areata by promoting inflammation and involving specific genes in hair and immune function.
Men with male pattern baldness may have a higher risk of heart problems.
30 citations
,
March 2015 in “Journal of Dermatology” Hair thickness differences help diagnose hair loss severity.
July 2024 in “Journal of Investigative Dermatology” Squaric acid dibutylester helps hair growth by increasing certain immune cells in the skin.
11 citations
,
October 2021 in “Carbohydrate Polymers” Ginkgo biloba polysaccharides may reduce inflammation and promote hair growth in mice with hair loss.
June 2023 in “Australasian Journal of Dermatology” Australian dermatologists are updating their prescriptions for male pattern baldness.
7 citations
,
May 2007 in “PubMed” Women with androgenetic alopecia (AGA) are more insulin resistant than healthy women, with various insulin sensitivity indices being higher in the AGA group. An oral glucose tolerance test is suggested for women with AGA.
2 citations
,
December 2018 in “International Journal of Dermatology” New grading scale accurately measures hair loss severity and treatment effectiveness.
March 2024 in “Healthcare” Stem cell treatment improved life quality and sexual function in women with hair loss.