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5α-reductase affects dopamine receptors linked to sensorimotor gating, which may help understand disorders like schizophrenia.

New targets for making and using brain-synthesized steroids could lead to better treatments for brain disorders and alcoholism.

Progesterone reduces anxiety and depression in female mice by increasing BDNF in the brain, needing 5α-reduction and estradiol.

Hormones control reproduction and are crucial for body balance.

New treatments for prostate cancer and BPH show promise, including novel compounds that target hormone synthesis and response.

The transcription factor Meis2 is essential for touch sensation and proper nerve development in touch receptors.

Spanish experts provided guidelines for treating skin side effects in cancer patients on new therapies, stressing early action and teamwork.

Meis2 is essential for touch sensation and proper nerve connection to touch receptors in certain skin areas of mice.

2-DG reduces seizures by enhancing brain inhibition through specific receptor activation.

14,15-EET may help reduce poststroke pain by affecting certain brain proteins.

AC-5216 reduces anxiety in mice through neurosteroids affecting GABAA receptors.

Olanzapine reduces stress-related anxiety in rats when given acutely.

Progesterone protects brain cells by converting to allopregnanolone and involving GABAA receptors.

Adjusting neurosteroid levels may help reduce alcohol withdrawal symptoms.

Isolation stress in rats reduces brain enzyme levels, affecting dopamine function.

New treatments are needed for PCOS that target its genetic, hormonal, and metabolic causes.

Progesterone increases alcohol tolerance and withdrawal anxiety, while DHEAS prevents them.

Testosterone increases 3α-androstanediol levels, which can be blocked by finasteride.

Testosterone affects brain behavior in complex and varied ways.

Midazolam's seizure prevention is partly due to increased neurosteroid production.

Allopregnanolone, a progesterone metabolite, helps reduce restraint effects on behavior.

Sodium valproate helps skin healing by affecting GABA and histone deacetylase.

PN hydrates skin; PDRN heals and regenerates skin and hair.

Microglia, the brain's immune cells, may contribute to Polycystic Ovary Syndrome (PCOS) by altering the female brain's structure and function, with kisspeptin neurons and GABA neurotransmitters also playing a role.

Weight loss improves PCOS symptoms and overall health.

Neuroactive steroids affect cocaine's rewarding effects through the ς₁ receptor.

TRPV4 helps cells repair tissue and reduce scarring by controlling calcium levels.

Chinese domestic goats have unique genetic traits due to domestication and geographic isolation.

A brain-made hormone can protect against memory-related brain damage caused by harmful proteins.

TRP channels in the skin are important for sensation and health, and targeting them could help treat skin disorders.