research Nanospanlastic vesicles as novel strategies for enhancing anti-glaucoma drug bioavailability
Nanospanlastic vesicles can improve glaucoma treatment by enhancing drug delivery to the eye.
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360-390 / 1000+ resultsresearch Advances in nitric oxide-releasing hydrogels for biomedical applications
research Minoxidil overdose with hypotension effectively managed with norepinephrine, rather than dopamine
research First-in-human phase 1 study of ETC-159 an oral PORCN inhbitor in patients with advanced solid tumours.
ETC-159 was safe up to 30 mg, but no tumor shrinkage was seen.
research EARLY CARDIAC DAMAGE FOLLOWING SINGLE AND COMBINED EXPOSURE TO LITHIUM CARBONATE AND LEAD ACETATE IN RATS: A TOXICOLOGICAL PERSPECTIVE
Lithium carbonate and lead acetate together harm the heart more than individually.
research MIL-88A derived zerovalent iron embedded mesoporous carbon with carbon black composite based electrochemical sensor for the detection of metol
The new sensor can detect a toxic chemical in water with high sensitivity and accuracy.
research Historical and Current Adenosine Receptor Agonists in Preclinical and Clinical Development
The document concludes that adenosine receptor agonists have potential for treating various conditions, but only a few are approved due to challenges like side effects and the need for selective activation.
research Gum Arabic Enhances Hair Follicle-Targeting Drug Delivery of Minoxidil Nanocrystal Dispersions
Gum arabic improves minoxidil delivery to hair follicles, enhancing hair growth.
research In Vitro and In Vivo Scalp Retention and Penetration of 99mTc-Minoxidil Solution
Thicker minoxidil solutions work better and need less frequent application.
research 414 A fitst-in-human study of BLZ-100 (tozuleristide) demonstrates tolerability and fluorescence contrast in skin cancer
BLZ-100 is safe for use in skin cancer surgery and may help identify cancerous tissue.
research Dyeing Your Hair with Graphene
Graphene-based hair dye is a safe, durable, and effective alternative to traditional black hair dyes.
research Painful, Unexplained Peripheral Neuropathy? Think Thallium Toxicity
If someone has unexplained nerve pain and hair loss, doctors should check for thallium poisoning.
research Two cases of low-prostate-specific antigen localized prostate cancer incidentally detected by computed tomography
CT scans can find serious prostate cancer even when PSA levels are low.
research Functionally enhanced placenta-derived mesenchymal stem cells inhibit adipogenesis in orbital fibroblasts with Graves’ ophthalmopathy
Enhanced stem cells from the placenta can help treat Graves' eye disease by stopping fat cell growth.
research Experimental and Finite Element Analysis of a Residual Hair Keratin‐based Hydrogel with Calcium for Atorvastatin Sequestration, Release, and In Vitro Activity
Keratin-based hydrogels with calcium are effective for delivering anti-fibrotic drugs.
research The Effect of Mushroom Beta‐Glucans from Solid Culture of Ganoderma lucidum on Inhibition of the Primary Tumor Metastasis
Mushroom beta-glucans from Ganoderma lucidum can reduce tumor size and metastasis in cancer.
research Functionally enhanced placenta-derived mesenchymal stem cells inhibit adipogenesis in orbital fibroblasts with Graves’ ophthalmopathy
Enhanced stem cells from the placenta can reduce fat buildup in eye tissue for Graves' disease.
research Antitumour and toxic effects on Wistar rats of two new platinum complexes
The new platinum complexes effectively increased survival in rats with tumors, despite some reversible side effects.
research pH sensitive nano layered double hydroxides reduce the hematotoxicity and enhance the anticancer efficacy of etoposide on non-small cell lung cancer
The nano-carrier makes etoposide safer and more effective against lung cancer.
research Demethylation of ITGAV accelerates osteogenic differentiation in a blast-induced heterotopic ossification in vitro cell culture model
Removing a methyl group from the ITGAV gene speeds up bone formation in a specific type of bone disease model.
research Development and characterization of poly(lactic-co-glycolic acid) (PLGA) nanoparticles with finasteride and in vivo evaluation of their efficacy in hair growth
Finasteride-loaded nanoparticles were successfully created for potential improved hair growth treatment.
research Research Progress of Sodium Alginate-Based Hydrogels in Biomedical Engineering
Sodium alginate-based hydrogels are promising for medical use due to their versatility and biocompatibility.
research Plasma-Polymerised Antibacterial Coating of Ovine Tendon Collagen Type I (OTC) Crosslinked with Genipin (GNP) and Dehydrothermal-Crosslinked (DHT) as a Cutaneous Substitute for Wound Healing
The GNP crosslinked scaffold with antibacterial coating is effective for rapid wound healing and infection prevention.
research Tyrosine kinase inhibition and grey hair
Imatinib can repigment grey hair, while SU11428 can cause temporary hair depigmentation.
research The selective androgen receptor modulator GTx‐024 (enobosarm) improves lean body mass and physical function in healthy elderly men and postmenopausal women: results of a double‐blind, placebo‐controlled phase II trial
Enobosarm significantly increased muscle mass and improved physical function in elderly men and postmenopausal women without serious side effects.
research Dynamically Cross-Linked Granular Hydrogels for 3D Printing and Therapeutic Delivery
The hydrogels are strong, self-healing, and good for 3D printing and delivering treatments.
research Cardiovascular Toxicities of Androgen Deprivation Therapy
ADT for prostate cancer may harm the heart, but GnRH antagonists might be safer.
research The hydroxypropyl‐β‐cyclodextrin‐minoxidil inclusion complex improves the cardiovascular and proliferative adverse effects of minoxidil in male rats: Implications in the treatment of alopecia
A new gel form of minoxidil is equally effective for hair growth and safer for the heart and other organs than the traditional solution.
research Rapid generation of homogenous tumor spheroid microtissues in a scaffold-free platform for high-throughput screening of a novel combination nanomedicine
A new triple drug system using nanoparticles effectively targets breast tumors in 3D models.
research Effect of injectable calcium alginate-amelogenin hydrogel on macrophage polarization and promotion of jaw bone osteogenesis
The hydrogel helps bone growth and healing in jaw and facial defects.