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The G60S Connexin43 mutation causes hair growth issues and poor hair quality in mice, similar to human ODDD patients.

A new TP63 mutation was found in a baby with EEC syndrome, showing the need for TREC testing to check for immune issues.

The study found that p63 needs signals from morphogens to help skin cells differentiate properly.

Different PADI isoforms help cells develop diverse functions.

Mesenchymal stem cells help heal wounds by using Cx43 hemichannels to improve tissue repair.

DAB labeling effectively identifies collagen type III and PDGFR in horse skin, but may show false positives.

A Chinese man with KID syndrome had a new mutation in the GJB2 gene.

A Chinese male with a new genetic mutation has a skin condition and severe urinary issues, with treatments having mixed success.

CNGA3, GLUD1, and SIRT1 are promising targets for treating aging and glioblastoma.

CTP-543 is generally safe for treating alopecia areata.

Chemistry42 effectively creates and optimizes new molecules for drug discovery.

CRISPR/Cas9 and prime editing can potentially fix skin disorder genes safely and effectively.

Hair follicle stem cell exosomes help nerve regeneration.

Hair follicle stem cell exosomes help nerve regeneration.

The study found a specific peptide that helps detect TGase 3 activity in skin and hair follicles.

ΔNp63α stops TAp73β from working in skin cancer by blocking its access to specific genes, not by directly interacting with it.

Epidermal stem cells don't use gap junctions to communicate.

Overexpressing 14-3-3σ in mice skin reduces cell growth and hair density.

SCUBE3 is a potential target for cancer and alopecia treatment but is challenging to target due to its varied roles.

A boy with Oculodentodigital syndrome had a unique GJA1 gene mutation causing his symptoms.

A new therapy for a skin blistering condition has not been developed yet.

Par3–mInsc and Gαi3 work together to ensure proper cell division orientation in skin development.

The DMI3 gene is essential for nodule development and symbiosis in certain plants.

Mouse Scube3 affects teeth, tongue, vibrissae, and eye development, but not facial structure or limb growth.

Mutations in the p63 gene affect skin adhesion, barrier integrity, and hair growth.

A genetic defect causes males in some Mediterranean populations to be born with ambiguous genitalia and develop male traits at puberty.