research What should it take to describe a substance or product as 'sperm-safe'
Products should be called 'sperm-safe' only after thorough, well-designed tests.
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research COVID-19: Understanding Inter-Individual Variability and Implications for Precision Medicine
The conclusion is that individual differences in COVID-19 severity are influenced by factors like age, sex, race, and genetics, which are important for personalized medicine.
research Menopause and aging, quality of life and sexuality
Menopause and aging can affect women's quality of life and sexuality, but hormone therapies may help alleviate these issues.
research Hair and scalp disorders in ethnic populations
Different hair care practices and conditions affect African American hair and scalp health, requiring specialized knowledge for treatment.
research Androgen Profiling by Liquid Chromatography–Tandem Mass Spectrometry (LC-MS/MS) in Healthy Normal-Weight Ovulatory and Anovulatory Late Adolescent and Young Women
The research found that anovulatory young women have higher androgen and hormone levels than those who ovulate, suggesting immature hormonal regulation rather than a specific condition.
research Mutant laboratory mice with abnormalities in hair follicle morphogenesis, cycling, and/or structure: An update
The document concludes that mouse models are crucial for studying hair biology and that all mutant mice may have hair growth abnormalities that require detailed analysis to identify.
research Characteristics of Androgenetic Alopecia in Asian
Asian hair loss differs from Europeans; consider individual needs and psychological well-being for treatment.
research The therapeutic use of androgens in women
Testosterone replacement may improve sexual desire and bone health in women with low androgen levels, but more research is needed on its long-term safety.
research Four days of simulated shift work reduces insulin sensitivity in humans
Working night shifts for four days can lower the body's ability to use insulin, which may increase the risk of type 2 diabetes.
research The novel mechanisms and applications of exosomes in dermatology and cutaneous medical aesthetics
Exosomes can improve skin health and offer new treatments for skin repair and rejuvenation.
research Improving translational research in sex-specific effects of comorbidities and risk factors in ischaemic heart disease and cardioprotection: position paper and recommendations of the ESC Working Group on Cellular Biology of the Heart
The document concludes that future heart disease research should account for sex-specific differences to improve diagnosis, treatment, and outcomes.
research Idiopathic Hirsutism*
The document concludes that more research is needed to understand excessive hair growth in women with normal hormone levels and regular ovulation.
research The biology of hair diversity
Hair diversity is influenced by complex genetics and environmental factors, requiring more research for practical solutions.
research The Androgen Receptor Antagonizes Wnt/β-Catenin Signaling in Epidermal Stem Cells
Androgen receptor activity blocks Wnt/β-catenin signaling, affecting hair growth and skin cell balance.
research Principles and mechanisms of regeneration in the mouse model for wound‐induced hair follicle neogenesis
Mice can grow new hair follicles after skin wounds through a process not involving existing hair stem cells, but requiring more research to understand fully.
research Sex steroid synthesis in human skin in situ: The roles of aromatase and steroidogenic acute regulatory protein in the homeostasis of human skin
Human skin produces sex hormones like estrogen and testosterone, influenced by ARO and StAR, which may affect skin elasticity and hair growth.
research Low-level laser therapy for the treatment of androgenetic alopecia in Thai men and women: a 24-week, randomized, double-blind, sham device-controlled trial
LLLT promotes hair growth and improves hair density safely in men and women.
research Hoxc-Dependent Mesenchymal Niche Heterogeneity Drives Regional Hair Follicle Regeneration
Hoxc genes control hair growth through Wnt signaling.
research Functional hair follicle regeneration: an updated review
Hair follicle regeneration possible, more research needed.
research Transient mitochondrial DNA double strand breaks in mice cause accelerated aging phenotypes in a ROS-dependent but p53/p21-independent manner
Damaging mitochondrial DNA in mice speeds up aging due to increased reactive oxygen species, not through the p53/p21 pathway.
research Therapeutic strategies for treating hair loss
The conclusion is that we need more effective hair loss treatments than the current ones, and these could include new drugs, gene and stem cell therapy, hormones, and scalp cooling, but they all need thorough safety testing.
research Identification of the Ovine Keratin-Associated Protein 22-1 (KAP22-1) Gene and Its Effect on Wool Traits
The gene KAP22-1 affects wool yield and fiber shape in sheep.
research Skin aging as a mechanical phenomenon: The main weak links
Skin aging is largely due to differences in stiffness and elasticity between skin layers, leading to wrinkles.
research Calcineurin/Nfatc1 signaling links skin stem cell quiescence to hormonal signaling during pregnancy and lactation
Hormones during pregnancy and lactation keep skin stem cells inactive, preventing hair growth.
research Androgen modulation of Wnt/β-catenin signaling in androgenetic alopecia
Androgens may block hair growth signals, targeting this could treat hair loss.
research Effect of Adenovirus-Mediated Expression of Sonic Hedgehog Gene on Hair Regrowth in Mice With Chemotherapy-Induced Alopecia
Using a gene therapy with the Sonic Hedgehog gene helps mice regrow hair faster after losing it from chemotherapy.
research Hypertension and Reproduction
Reproductive factors can increase hypertension risk and affect cardiovascular health.
research A Clinical and Biological Guide for Understanding Chemotherapy-Induced Alopecia and Its Prevention
Scalp cooling can help prevent chemotherapy-induced hair loss with a 50-90% success rate and is safe for patients.
research Platelet-derived growth factor signaling modulates adult hair follicle dermal stem cell maintenance and self-renewal
PDGF signaling is crucial for maintaining and renewing hair follicle stem cells, which could help treat hair loss.
research Facial Hair Restoration
Facial hair restoration is generally successful and satisfying for patients when done with quality techniques and realistic expectations.