330 citations
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December 2009 in “Cell stem cell” SKPs are similar to adult skin stem cells and could help in skin repair and hair growth.
205 citations
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March 2012 in “Science Translational Medicine” PGD2 stops hair growth and is higher in bald men with AGA.
144 citations
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September 2012 in “Genes & development” Aging causes skin stem cells to work less effectively.
133 citations
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September 2013 in “Nature Reviews Molecular Cell Biology” Different types of stem cells and their environments are key to skin repair and maintenance.
85 citations
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July 2012 in “Cold Spring Harbor perspectives in biology” The skin protects the body and is constantly renewed by stem cells; disruptions can lead to cancer.
77 citations
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August 2025 in “Signal Transduction and Targeted Therapy” Extracellular vesicles show promise for treating diseases but face challenges in development and regulation.
76 citations
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July 2019 in “Cellular and Molecular Life Sciences” Stem cells are crucial for tissue growth, cancer treatment, and disease modeling, but challenges remain in clinical use.
70 citations
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February 2019 in “The journal of immunology/The Journal of immunology” Short-chain fatty acids from *Cutibacterium acnes* cause skin inflammation, contributing to acne.
60 citations
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September 2015 in “Expert Review of Clinical Immunology” Lymphocytes, especially CD8+ T cells, play a key role in causing alopecia areata, and targeting them may lead to new treatments.
56 citations
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February 2010 in “PLOS ONE” Blocking Wnt signaling in young mice causes thymus shrinkage and cell loss, but recovery is possible when the block is removed.
54 citations
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December 2014 in “Wound Repair and Regeneration” PRP injections may improve hair thickness and density in female hair loss patients.
48 citations
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August 2018 in “Nature Communications” JunB is crucial for maintaining healthy skin and hair follicles.
47 citations
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June 2019 in “Nature Communications” Noncoding dsRNA boosts hair growth by activating TLR3 and increasing retinoic acid.
36 citations
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January 2019 in “Nature communications” High lactate dehydrogenase activity is not necessary for the growth of squamous cell carcinoma.
34 citations
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January 2015 in “Biomedicine and Biotechnology” Bio-fortification through plant breeding can improve the nutritional value of staple crops by adding essential minerals.
29 citations
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December 2016 in “The EMBO Journal” Gata6 is important for protecting hair growth cells from DNA damage and keeping normal hair growth.
25 citations
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November 2018 in “Cell reports” The study concluded that specific proteins are necessary to maintain the structure that holds epithelial cells tightly together.
23 citations
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August 2018 in “Biochimica and biophysica acta. Molecular and cell biology of lipids” Different sPLA2 enzymes affect immunity, skin and hair health, reproduction, and may be potential targets for therapy.
23 citations
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June 2012 in “PLOS ONE” KLF4 is important for maintaining skin stem cells and helps heal wounds.
11 citations
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February 2022 in “Scientific Reports” CD26+ fibroblasts improve skin healing and integration better than CD26− fibroblasts.
11 citations
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January 2022 in “Theranostics” Wnt4 is essential for heart repair and could be a target for heart disease treatment.
9 citations
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October 2022 in “Nature Communications” The DiLiCre mouse model is an effective tool for precise genome editing using light.
8 citations
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February 2020 in “Aesthetic Surgery Journal” Adding cells to fat grafts improves hair regrowth in early baldness, but effects lessen over time.
7 citations
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January 2023 in “Frontiers in cell and developmental biology” Celsr1 is crucial for skin cell alignment, while Celsr2 has little effect on this process.
6 citations
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July 2018 in “Advances in Clinical and Experimental Medicine” Different body parts have varying levels of certain hair follicle markers.
5 citations
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March 2024 in “Acta Scientiarum Polonorum Technologia Alimentaria” Underutilized seeds like jackfruit, Indian almond, and tamarind have valuable nutrients and compounds that can be used sustainably in various industries.
4 citations
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August 2018 in “Facial Plastic Surgery Clinics of North America” Platelet-Rich Plasma (PRP), a protein-rich extract from a patient's blood, shows promise in improving hair density, thickness, and quality, but the best method of use and number of treatments needed for noticeable results are still unclear.
4 citations
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January 2013 in “Advances in Experimental Medicine and Biology” Certain transcription factors are key in controlling skin stem cell behavior and could impact future treatments for skin repair and hair loss.
3 citations
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January 2024 in “Signal transduction and targeted therapy” Lymphatic vessels are essential for health and can be targeted to treat various diseases.
June 2026 in “Scholarly review .” Endocrine-disrupting chemicals cause irreversible harm to children's development, increasing disease risk.