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      Clinical Snippets: Discoveries in Dermatology and Related Fields

      research Clinical Snippets

      November 2003 in “Journal of Investigative Dermatology”
      Topical Imiquimod may fight vascular tumors by affecting blood vessels or the immune system, low iron might be linked to some hair loss, removing the top skin layer helps vitamin C get in, genetic testing helps diagnose skin conditions, and too much iron could worsen skin inflammation.
      The Rotterdam Study: 2014 Objectives and Design Update

      research The Rotterdam Study: 2014 objectives and design update

      266 citations , November 2013 in “European Journal of Epidemiology”
      The Rotterdam Study aims to understand disease causes in the elderly and has found new risk factors and genetic influences on various conditions.
      Polycystic Ovary Syndrome in Adolescents

      research PCOS in adolescents

      71 citations , November 2009 in “Best Practice & Research in Clinical Obstetrics & Gynaecology”
      PCOS in teens is hard to diagnose, linked to genetics and lifestyle, and managed with weight loss and medication.
      Acne

      research ACNE

      58 citations , January 1997 in “Dermatologic Clinics”
      Acne significantly affects mental health and quality of life, with research suggesting hormonal and genetic factors in its development and emphasizing early treatment to prevent scarring.
      Novel TMEM173 Mutation and the Role of Disease-Modifying Alleles

      research Novel TMEM173 Mutation and the Role of Disease Modifying Alleles

      47 citations , December 2019 in “Frontiers in immunology”
      A new mutation in the STING protein causes a range of symptoms and its severity may be affected by other genetic variations; treatment with a specific inhibitor showed improvement in one patient.
      Heterogeneity of Neural Crest-Derived Melanocytes

      research Heterogeneity of neural crest-derived melanocytes

      8 citations , February 2013 in “Central European Journal of Biology”
      Melanocytes are diverse cells important for pigmentation and skin health, influenced by genetics and environment.
      Effects and Mechanism of Nutrients on Root Hair Growth

      research Effects and Mechanism of Nutrients on Root Hair Growth

      December 2017 in “International Journal of Current Research in Biosciences and Plant Biology”
      Nutrients and hormones affect root hair growth, but more research is needed to understand the genetic mechanisms.
      Cutaneous Lupus Erythematosus: Overview and Treatment

      research Cutaneous Lupus Erythematosus

      January 2017 in “Springer eBooks”
      The document concludes that Cutaneous Lupus Erythematosus has different forms, is influenced by genetic and environmental factors, and can be treated with various medications, but more targeted therapies are needed.
      Central Centrifugal Cicatricial Alopecia

      research Central centrifugal cicatricial alopecia

      72 citations , July 2008 in “Dermatologic Therapy”
      CCCA is a scarring hair loss condition mainly in African descent women, possibly caused by genetics and hairstyling, treated with gentle hair care and medications.
      Hair Loss in Women: A Study at Sheffield Royal Infirmary (1959-1966)

      research HAIR LOSS IN WOMEN

      39 citations , October 1967 in “British Journal of Dermatology”
      Hair loss in women often doesn't follow a pattern, isn't linked to age, may be genetic, and can be related to thyroid issues or other health factors.
      The Pathogenesis of Alopecia Areata in Rodent Models

      research The Pathogenesis of Alopecia Areata in Rodent Models

      23 citations , June 2003 in “Journal of Investigative Dermatology Symposium Proceedings”
      Alopecia Areata is an autoimmune disease affecting hair follicles, influenced by genetic and environmental factors, with rodent models being essential for research.
      Discoid Lupus Erythematosus: Comprehensive Overview and Management

      research Discoid Lupus Erythematosus

      July 2018 in “Elsevier eBooks”
      Discoid Lupus Erythematosus often causes scarring hair loss, is influenced by genetics and environment, and requires early treatment to prevent worsening.
      Hair Loss in Children

      research Hair loss in children.

      6 citations , May 1993 in “Archives of Disease in Childhood”
      Children's hair loss can be caused by many factors, including autoimmune diseases, emotional stress, genetics, and infections, with treatment and prognosis varying.
      Stem Cell Heterogeneity and Plasticity in Epithelia

      research Stem Cell Heterogeneity and Plasticity in Epithelia

      129 citations , May 2015 in “Cell Stem Cell”
      Different types of stem cells exist within individual skin layers, and they can adapt to damage, transplantation, or tumor growth. These cells are regulated by their environment and genetic factors. Tumor growth is driven by expanding, genetically altered cells, not long-lived mutant stem cells. There's evidence of cancer stem cells in skin tumors. Other cells, bacteria, and genetic factors help maintain balance and contribute to disease progression. A method for growing mini organs from single cells has been developed.
      Basics of Androgen Synthesis and Action

      research Basics of androgen synthesis and action

      35 citations , May 2022 in “Baillière's best practice and research in clinical endocrinology and metabolism/Baillière's best practice & research. Clinical endocrinology & metabolism”
      Androgens like testosterone are important hormones for both men and women, made differently in each sex and affecting the body by regulating genes and quick interactions with cell components.