research 9. Immunology and Genetics
The document concludes that Borrelia afzelii causes a skin condition in France, a gene is linked to hair loss in Caucasian women, and various genetic mutations affect skin diseases.
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research Hypoxia-Derived Mesenchymal Stem Cell Exosomes Downregulate CXCL12 and Upregulate IL-10 Expression in a Murine Model of Androgenic Alopecia
EH-MSCs may help treat hair loss by reducing inflammation.
research Telomere Dynamics and Telomerase in the Biology of Hair Follicles and their Stem Cells as a Model for Aging Research
Hair follicle studies suggest that maintaining telomere length could help treat hair loss and graying, but it's uncertain if mouse results apply to humans.
research The E6/E7 oncogenes of human papilloma virus and estradiol regulate hedgehog signaling activity in a murine model of cervical cancer
HPV genes and estradiol increase a cancer-related signaling pathway, which may be targeted for cervical cancer treatment.
research Hair regrowth through wound healing process after ablative fractional laser treatment in a murine model
Laser treatment helped regrow hair in mice by activating a key growth pathway.
research Involvement of the central hypothalamic-pituitary-adrenal axis in hair growth and melanogenesis among different mouse strains
Stress can slow hair growth and affect skin color by impacting the body's stress response system.
research The extract of Thujae occidentalis semen inhibited 5α-reductase and androchronogenetic alopecia of B6CBAF1/j hybrid mouse
Thujae occidentalis semen extract may help treat male pattern baldness by blocking a hair loss-related enzyme and reducing hair loss in mice.
research Platelet‐rich plasma for androgenic alopecia: A randomized, placebo‐controlled, double‐blind study and combined mice model experiment
PRP injections promote hair growth and increase hair density in androgenic alopecia.
research Overexpression of alkaline phosphatase improves the hair-inductive capacity of cultured human dermal papilla spheres
Increasing alkaline phosphatase in human skin cells helps to grow more hair.
research The population dynamics of cancer: a Darwinian perspective
Cancer development is like natural selection, involving mutated cells and environmental factors.
research Role of thymosin beta 4 in hair growth
Thymosin beta 4 may help hair growth and could be a treatment for hair issues.
research KLK5 and KLK7 Ablation Fully Rescues Lethality of Netherton Syndrome-Like Phenotype
Removing both KLK5 and KLK7 proteins can prevent death and skin issues in Netherton syndrome.
research Sic Transit Gloria: Farewell to the Epidermal Transit Amplifying Cell?
New research suggests that skin cell renewal may not require a special type of cell previously thought to be essential.
research Modeling of chronic radiation-induced cystitis in mice
Researchers developed a mouse model that successfully mimics the bladder damage seen in humans after radiation therapy.
research Inducible cre-mediated N-ras activation and PTEN inactivation in transgenic mouse melanocytes requires keratinocyte hyperplasia to elicit a melanocyte pathology
Melanocyte pathology requires keratinocyte hyperplasia and regulation dysfunction.
research Blockade of S100A3 activity inhibits murine hair growth
Stopping S100A3 activity slows down hair growth in mice.
research Clinically relevant aberrant Filip1l DNA methylation detected in a murine model of cutaneous squamous cell carcinoma
Increased methylation of the Filip1l gene may contribute to aggressive skin cancer.
research 606 Connecting signaling dynamics with cell fates in live mice
Stem cells control their future role by changing ERK signal timing, affecting tissue regeneration and cancer.
research Targeted Knockout of β-Catenin in Adult Melanocyte Stem Cells Using a Mouse Line, Dct::CreERT2, Results in Disrupted Stem Cell Renewal and Pigmentation Defects
Removing β-catenin in certain stem cells causes hair whitening and pigmentation issues.
research Metabolic and pathologic profiles of human LSS deficiency recapitulated in mice
Mice with LSS deficiency showed hair loss and cataracts, similar to humans, and can help in understanding and treating this condition.
research Angora Mouse Mutation: Altered Hair Cycle, Follicular Dystrophy, Phenotypic Maintenance of Skin Grafts, and Changes in Keratin Expression
The angora mouse mutation causes long hair and hair defects due to a gene deletion.
research Regeneration Genetics
Understanding tissue regeneration in animals can improve regenerative medicine.
research Genetic disorders of keratin: are scarring alopecias a sub-set?
Keratin mutations may cause scarring alopecia by damaging hair structure.
research Mice with Alopecia, Osteoporosis, and Systemic Amyloidosis Due to Mutation in Zdhhc13, a Gene Coding for Palmitoyl Acyltransferase
A gene mutation in mice causes hair loss, weak bones, and protein buildup, showing how protein processing issues can lead to diseases.
research CD34 defines melanocyte stem cell subpopulations with distinct regenerative properties
CD34+ and CD34- melanocyte stem cells have different regenerative abilities.
research Evaluation of hair follicles as a surrogate tissue for pharmacodynamics response in xenograft tumors
Hair follicles can be used to quickly assess drug effects in cancer treatment.
research Human hair production by scalp samples grafted onto nude mice. Biochemical data on normal human hair and the genetic defect trichothiodystrophy
Grafted human scalp samples on mice can produce human hair, useful for studying hair genetics.
research A genome-wide association scan in admixed Latin Americans identifies loci influencing facial and scalp hair features
Genetic factors influence hair traits like shape, color, and greying in Latin Americans.
research Perspectives of Kennedy's disease
Kennedy's disease leads to muscle weakness and sensory issues, has no cure but manageable symptoms, and future treatments look promising.
research Comparative Anatomy of Mouse and Human Nail Units
Mouse nails are similar to human nails, making them useful for studying nail diseases.