research Hair today, gone tomorrow
Two drugs, tofacitinib and ruxolitinib, may help regrow hair by activating hair follicles.
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research Reversal of alopecia areata in a mouse model of human hair loss by daily dietary administration of a proprietary extract of North American ginseng (Panax Quinquefolius)
North American ginseng extract helped regrow hair in balding mice.
research Type 2 Diabetes, Metabolic Syndrome and Lipid Metabolism
Type 2 diabetes in youth is increasing, with high treatment failure rates and more severe than Type 1; certain drugs can lower lipid levels effectively with varying side effects, and apples may benefit heart health like statins but with fewer side effects.
research Introduction to Innovations in the Immunology and Clinical Science of Alopecia Areata
New research is helping develop better treatments for alopecia areata.
research Risk factors for prostate cancer: a case-control study investigating selected key exposures and their interactions with predisposition genes
Age, race, family history, and certain genetic factors increase prostate cancer risk.
research A Comprehensive Review on Metabolic Syndrome
Managing metabolic syndrome needs both lifestyle changes and medical treatments.
research ATP-dependent chromatin remodeling during mammalian development
ATP-dependent chromatin-remodeling complexes are crucial for gene regulation, cell differentiation, and organ development in mammals.
research Early inductive events in ectodermal appendage morphogenesis
Early development of hair, teeth, and glands involves specific signaling pathways and cellular interactions.
research Pharmacologic inhibition of JAK-STAT signaling promotes hair growth
Blocking JAK-STAT signaling can lead to hair growth.
research The Harmonies Played by TGF-β in Stem Cell Biology
TGF-β is crucial for controlling stem cell behavior and changes in its signaling can lead to diseases like cancer.
research Cutaneous lupus erythematosus: a review
Patients with certain skin symptoms and high ANA titers should be monitored for potential systemic lupus.
research Comparison of viral RNA–host protein interactomes across pathogenic RNA viruses informs rapid antiviral drug discovery for SARS-CoV-2
Cepharanthine and Trifluoperazine are effective against SARS-CoV-2.
research Hair follicle stem cell differentiation is inhibited through cross‐talk between Wnt/β‐catenin and androgen signalling in dermal papilla cells from patients with androgenetic alopecia
Androgens block hair growth by disrupting cell signals; targeting GSK-3 may help treat hair loss.
research Obesity and polycystic ovary syndrome
Obesity increases the risk of developing polycystic ovary syndrome, and weight loss can improve the condition.
research The Senescence–Stemness Alliance – A Cancer-Hijacked Regeneration Principle
Cancer can hijack the body's cell repair system to promote tumor growth, and targeting this process may improve cancer treatments.
research Immune deficiency–related enteropathy-lymphocytopenia-alopecia syndrome results from tetratricopeptide repeat domain 7A deficiency
A deficiency in the TTC7A gene causes immune problems, gut issues, and hair loss.
research Mutant laboratory mice with abnormalities in hair follicle morphogenesis, cycling, and/or structure: An update
The document concludes that mouse models are crucial for studying hair biology and that all mutant mice may have hair growth abnormalities that require detailed analysis to identify.
research FGFR2 is associated with hair thickness in Asian populations
A gene variation is linked to hair thickness in Asians.
research Men with Kennedy disease have a reduced risk of androgenetic alopecia
Men with Kennedy disease have less chance of hair loss.
research Melatonin promotes Cashmere goat (Capra hircus) secondary hair follicle growth: a view from integrated analysis of long non-coding and coding RNAs
Melatonin helps Cashmere goats grow more hair by affecting certain genes and cell pathways.
research Signalling couples hair follicle stem cell quiescence with reduced histone H3 K4/K9/K27me3 for proper tissue homeostasis
Certain signals are important for reducing specific chemical markers on hair follicle stem cells during rest periods, which is necessary for healthy hair growth.
research Variation in the caprine keratin-associated protein 15-1 (KAP15-1) gene affects cashmere fibre diameter
The KRTAP15-1 gene affects cashmere fiber thickness in goats.
research Phosphatidylinositol‐specific phospholipase C2 functions in auxin‐modulated root development
A protein called PLC2 is important for the growth and development of plant roots influenced by auxin.
research Breakdown of Immune Tolerance in AIRE-Deficient Rats Induces a Severe Autoimmune Polyendocrinopathy–Candidiasis–Ectodermal Dystrophy–like Autoimmune Disease
AIRE-deficient rats developed severe autoimmune disease similar to APECED, useful for testing treatments.
research Biallelic HEPHL1 variants impair ferroxidase activity and cause an abnormal hair phenotype
Mutations in the HEPHL1 gene cause abnormal hair and cognitive issues.
research Getting to the Core of the Dermal Papilla
The document concludes that understanding dermal papilla cells is key to improving hair regeneration treatments.
research Estimation methods for human circadian phase by use of peripheral tissues
New method uses hair follicle cells to estimate human body clock phase, potentially improving sleep disorder diagnosis.
research Androgenetic Alopecia: Relationship to Anthropometric Indices, Blood Pressure and Life-Style Habits
Men with hair loss have higher BMI, waist size, blood pressure, and are linked to smoking and inactivity.
research The intragenic mRNA-microRNA regulatory network during telogen-anagen hair follicle transition in the cashmere goat
The research found that a complex gene network, controlled by microRNAs, is important for hair growth in cashmere goats.
research Androgenetic alopecia as an indicator of metabolic syndrome and cardiovascular risk
Hair loss may indicate higher heart risk and metabolic issues.