research Alopecia areata: a review of diagnosis, pathogenesis and the therapeutic landscape
New treatments for alopecia areata show promise, but standardized guidelines are needed.
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300-330 / 1000+ results research Investigation of hub genes and immune infiltration in androgenetic alopecia using bioinformatics analysis
Immune activities and specific genes are important in male pattern baldness.
research Alopecia areata. Actualidad y perspectivas
Alopecia areata needs new treatments targeting autoimmune processes due to its emotional impact and variable treatment responses.
research The Mechanism and Research Progress of Skin Microbiota in Pathogenesis of Acne
Restoring skin microbial balance may help treat acne.
research Fibroblasts: Origins, definitions, and functions in health and disease
Fibroblasts are crucial for tissue repair and inflammation, and understanding them can help treat fibrotic diseases.
research The IL-23/IL-17 Pathway in Inflammatory Skin Diseases: From Bench to Bedside
Targeting the IL-23/IL-17 pathway effectively treats several inflammatory skin diseases.
research The endocannabinoid system of the skin. A potential approach for the treatment of skin disorders
Targeting the skin's endocannabinoid system could help treat skin disorders.
research Pulmonary Edema in COVID-19 Patients: Mechanisms and Treatment Potential
Targeting abnormal lung fluid metabolism could reduce COVID-19 deaths and ventilator use.
research Minoxidil may suppress androgen receptor-related functions
Minoxidil can reduce functions related to androgen receptors.
research Skin cancer: understanding the journey of transformation from conventional to advanced treatment approaches
New treatments like nanotechnology show promise in improving skin cancer therapy.
research Bioengineered microneedles and nanomedicine as therapeutic platform for tissue regeneration
Bioengineered microneedles and nanomedicine offer promising, precise treatments for tissue regeneration.
research Biomimetic Cell Membrane‐Coated Scaffolds for Enhanced Tissue Regeneration
Biomimetic cell membrane-coated scaffolds significantly enhance tissue regeneration by mimicking natural cellular environments.
research METTL1-mediated m7G tRNA modification drives papillary thyroid cancer progression and metastasis by regulating the codon-specific translation of TNF-α
Targeting METTL1 may help slow papillary thyroid cancer growth and spread.
research The role of vitamin D receptor signaling in hair follicle health and alopecia: Current understanding and therapeutic implications
Vitamin D receptor is crucial for hair health and may help treat hair loss.
research 478 Mutation-specific siRNA Knockdown of GJB2 − Potential gene therapy for Keratitis-ichthyosis-deafness Syndrome
Targeted siRNA therapy may be a promising treatment for KID syndrome by reducing mutant gene expression and improving cell communication.
research On the effects of testosterone on brain behavioral functions
Testosterone affects brain behavior in complex and varied ways.
research The genetics of alopecia areata: New approaches, new findings, new treatments
New genetic discoveries may lead to better treatments for alopecia areata.
research A novel therapeutic paradigm for patients with extensive alopecia areata
New treatments targeting immune pathways show promise for severe hair loss but need more research for safety and effectiveness.
research Cytoskeletal Regulation of Dermal Regeneration
Targeting the actin cytoskeleton could improve skin healing and reduce scarring.
research Mechanisms of tolerance and potential therapeutic interventions in Alopecia Areata
Targeting immune tolerance issues in Alopecia Areata could restore hair growth and maintain remission.
research Wnt is back in drugmakers' sights, but is it druggable?
Drugmakers are optimistic about targeting the Wnt pathway for new treatments despite past challenges.
research Langerin+ Dendritic Cells in Cutaneous Fibrosis: The TGF-β1 Signaling Axis
Targeting specific cell interactions may help treat skin fibrosis.
research Tregs: Where We Are and What Comes Next?
The conclusion is that Treg-targeted therapies have potential, but more knowledge of Treg biology is needed for effective treatments, including for cancer.
research Revising the role of the androgen receptor in breast cancer
The document concludes that targeting the androgen receptor may be a promising breast cancer treatment, especially for certain types.
research Nano-PROTACs: state of the art and perspectives
Nano-PROTACs could improve drug targeting and delivery by using nanotechnology.
research Drug repositioning: current approaches and their implications in the precision medicine era
Drug repositioning is becoming more targeted and efficient with new technologies, offering personalized treatment options and growing interest in the field.
research Signaling pathways in the mechanisms of drug action
Signaling pathways are key targets for developing effective drugs.
research The dihydrotestosterone (DHT) hypothesis of prostate cancer and its therapeutic implications
The document suggests that targeting the hormone DHT could be a more effective treatment for prostate cancer than targeting testosterone.
research Effects of sex steroid hormones and their metabolites on neuronal injury caused by oxygen-glucose deprivation/reoxygenation in organotypic hippocampal slice cultures
Progesterone and testosterone protect brain cells from damage through specific pathways.
research Implications of neuroimaging for the treatment of epilepsy
Neuroimaging suggests that treatments targeting brain steroids could help control epilepsy, especially types linked to the menstrual cycle.