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Flutamide caused damage to male rat reproductive organs and may affect fertility.

Compartmentalized organization might be crucial for stem cells to effectively respond to growth or injury.

Male hair loss is caused by inactive hair follicle stem cells.

Deleting Snai2 and Snai3 causes fatal autoimmunity.

GRK2 is essential for healthy hair follicle function, and its absence can lead to hair loss and cysts.

Zinc deficiency causes reversible hair loss by disrupting hair growth and stem cell function.

An imbalanced gut and lack of biotin can cause hair loss in mice.

Removing the ATR gene in adult mice causes rapid aging and stem cell loss.

Mice lacking a key DNA methylation enzyme in skin cells have a lower chance of activating stem cells necessary for hair growth, leading to progressive hair loss.

Hair can regrow after certain stem cells are lost because other stem cells can take over their role.

Lack of a certain enzyme causes hair to grey early by damaging stem cells, but an antioxidant can help prevent this.

Deleting the p63 gene in certain cells causes problems in thymus development and severe hair loss in mice.

Nestin marks cells that can become a specific type of skin cell in hair follicles of both developing and adult mice.

Sox10 is important for hair follicle development and hair growth cycles.

Aging mice have slower hair regeneration due to changes in signal balance, but the environment, not stem cell loss, controls this, suggesting treatments could focus on environmental factors.

NF-κB is crucial for different stages and types of hair growth in mice.

BMP and Wnt signaling balance controls hair follicle stem cell activity and hair growth.

MicroRNA-205 helps hair grow by changing the stiffness and contraction of hair follicle cells.

Zinc deficiency disrupts hair growth and cycle, but zinc supplements can fix this.

Brg1 is crucial for keeping hair follicle stem cells and repairing skin, working with the Sonic Hedgehog pathway to promote hair growth.

Deleting the BRD4 protein in certain skin cells causes hair loss and skin inflammation.

Basal cell carcinomas in mice can start from hair follicle stem cells and other skin cell types, depending on signaling levels.

Lipocalin-Type Prostaglandin D2 Synthase (L-PGDS) is a protein that plays many roles in the body, including sleep regulation, pain management, food intake, and protection against harmful substances. It also affects fat metabolism, glucose intolerance, cell maturation, and is involved in various diseases like diabetes, cancer, and arthritis. It can influence sex organ development and embryonic cell differentiation, and its levels can be used as a diagnostic marker for certain conditions.

Scientists restored fertility in male mice lacking a key fertility gene by using a modified gene.

Adult tissue stem cells can adapt and switch roles to help repair and maintain the body.

MicroRNA-205 helps hair regrow by making hair follicle stem cells less stiff.

Circadian clock genes are important for hair growth and may affect aging-related hair loss and graying.

Dying cells can help with faster healing and new hair growth by releasing a growth-promoting molecule.

Nestin-expressing cells turn into a specific type of skin cell in hair follicles during development and in adults.

The circadian clock affects skin stem cell behavior, impacting aging and cancer risk.