research Computer-Aided Designing Peptide Inhibitors of Human Hematopoietic Prostaglandin D2 Synthase Combined Molecular Docking and Molecular Dynamics Simulation
Two peptides, RMYYY and VMYMI, may be effective anti-inflammatory drugs.
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research Potential of nano-phytochemicals in cervical cancer therapy
Nano-sized plant-based chemicals could improve cervical cancer treatment by being more effective and causing fewer side effects than current methods.
research Cytotoxic Potential of Mangifera indica L var Arumanis Rind Extract and Fraction Against T47D Cells with Microtetrazolium (MTT) Method
Arumanis mango rind extract and its fractions can kill breast cancer cells, especially the ethanol extract and ethyl acetate fraction.
research Unsaturated Halogenated Hydrocarbons
These chemicals can be toxic and cause health issues like irritation, liver damage, and cancer.
research Lipid-based liquid crystals as drug delivery vehicles for antimicrobial peptides
Cubosomes enhance antimicrobial peptide stability and effectiveness.
research Deep facial mycosis due to Trichophyton verrucosum—molecular genetic identification of the dermatophyte in paraffin‐embedded tissue—case report and review of the literature
An 80-year-old man's deep beard infection was cured with oral terbinafine after identifying the fungus Trichophyton verrucosum.
research Apoptosis in growing hair follicles following gamma-irradiation and application for the evaluation of radioprotective agents.
Radiation increases cell death in hair follicles, but certain treatments can protect against this effect.
research Dissolving microneedles incorporating kopexil multicomponent crystals for improved transdermal delivery
Multicomponent crystals in microneedles improve drug delivery for hair loss treatment.
research The role of Glucosylceramides in Keratinocyte Differentiation and Epidermal Barrier Function
Glucosylceramides are essential for healthy skin and proper wound healing.
research Kaempferol Rhamnosides from Geranium sibiricum as Aldose Reductase Inhibitors and Their Content by HPLC Analysis
Geranium sibiricum may help manage diabetic complications by inhibiting a key enzyme.
research Dermatological drugs and topical agents
Certain skin drugs and topical agents, including some natural extracts and fragrances, can cause allergic reactions. Some hair dyes and extensions, as well as minoxidil, a hair growth treatment, can also cause allergies. Botulinum toxin A can effectively reduce sweat but may have temporary side effects.
research Cytostatics and immunosuppressive drugs
Some cancer and immune system drugs can cause serious side effects, including heart, lung, nerve, and organ damage, which need careful monitoring and management.
research A Transition State Analogue of 5′-Methylthioadenosine Phosphorylase Induces Apoptosis in Head and Neck Cancers
MT-DADMe-ImmA can selectively kill head and neck cancer cells without harming normal cells.
research Molecular Docking and Molecular Dynamics Analysis of Phytochemical Compounds from Nutmeg Fruit (Myristica fragrans Houtt.) on Androgen Receptor (4K7A) as Anti-Alopecia Therapy
Geranylgeraniol from nutmeg may effectively treat hair loss, similar to finasteride and better than minoxidil.
research A Facile Synthesis of Mollugin
Mollugin may help treat diseases and boost hair growth and anti-aging.
research Rosmarinus officinalis L. (Rosemary) Extracts Containing Carnosic Acid and Carnosol are Potent Quorum Sensing Inhibitors of Staphylococcus aureus Virulence
Rosemary extracts with carnosic acid and carnosol can reduce the harmfulness of Staphylococcus aureus without stopping its growth.
research A Porcine Model for the Development and Testing of Preoperative Skin Preparations
Povidone iodine reduced skin bacteria more than chlorhexidine gluconate, but neither met FDA reduction standards.
research Parasitic angiosperms, semagenesis and general strategies for plant–plant signaling in the rhizosphere
Reactive oxygen species are key for parasitic plant attachment and affect root development in various plants.
research Application of Marine Microbial Natural Products in Cosmetics
Marine microbes could be used in cosmetics for sun protection, skin care, and possibly preventing hair loss.
research Repurposing Finasteride as a quorum sensing inhibitor in Pseudomonas aeruginosa
Finasteride may help treat Pseudomonas aeruginosa infections by reducing its harmful activities.
research 554 Repurposing a clinical antimalarial for the therapeutic induction of lethal ER stress targeting BRAF-kinase inhibitor-resistant malignant melanoma
Mefloquine, an antimalarial drug, is effective in killing melanoma cells resistant to other treatments by causing lethal stress in the cells.
research Phytochemical analysis and antibacterial activities of Avicennia marina (Forssk.) Vierh. extracts against Vancomycin-resistant Enterococcus faecium
Avicennia marina leaf extract can fight Vancomycin-resistant bacteria.
research Multi-Approach Assessment of Albizia saponaria Bioactivity Against Dandruff-Related Bacteria and Fungi
Albizia saponaria stem bark shows promise as a natural antidandruff treatment.
research Managing the adverse effects of cytotoxic chemotherapy at the level of primary healthcare
Primary healthcare clinics are key in managing chemotherapy side effects using various medications and treatments.
research A Honey Trap for the Treatment of Acne: Manipulating the Follicular Microenvironment to ControlPropionibacterium acnes
The conclusion suggests a new acne treatment that controls bacteria by reducing water in the skin's pores using sugar-like substances.
research Lysocellin, a metabolite of the novel drug ‘alopestatin’, induces G1 arrest and prevents cytotoxicity induced by etoposide
Lysocellin helps stop cell damage from etoposide and may prevent hair loss.
research Autophagy-related protein 12 associates with anti-apoptotic B cell lymphoma-2 to promote apoptosis in gentamicin-induced inner ear hair cell loss
Blocking autophagy increases survival of inner ear hair cells exposed to gentamicin.
research Pyrene Excimer Nucleic Acid Probes for Biomolecule Signaling
Pyrene excimer nucleic acid probes are promising for detecting biomolecules accurately with potential for biological research and drug screening.
research Which chemicals should be grouped together for mixture risk assessments of male reproductive disorders?
Group a wide range of chemicals, not just phthalates, for assessing risks to male reproductive health.
research New fluorogenic probes for neutral and alkaline ceramidases
New probes were created to effectively measure specific enzymes involved in fat metabolism, which could help develop new drugs.