18 citations
,
June 2018 in “Journal of Dental Research” Msx2 is essential for proper enamel formation by preventing abnormal cell transformation.
16 citations
,
August 2019 in “Cell Proliferation” Keratinocytes help keep hair follicle cells and skin cells separate in 3D cultures, which is important for hair growth research.
The human scalp has different types of pigment cells in hair follicles with varying abilities to produce pigment.
27 citations
,
January 2006 in “Colloids and Surfaces B: Biointerfaces” Researchers found that bulge cells from human hair can grow quickly in culture and have properties of hair follicle stem cells, which could be useful for skin treatments.
November 2022 in “Journal of Investigative Dermatology” DermaCult™ Keratinocyte Expansion Medium allows human skin cells to grow longer while keeping their ability to develop properly.
December 2004 in “Reproduction Fertility and Development” Porcine hair follicles are useful for studying keratinocyte function, with galectin-1 as a potential stem cell marker.
6 citations
,
August 2008 in “Journal of Forensic Sciences” Recognizing specific tissue types on telogen hair roots can improve DNA typing.
36 citations
,
December 2004 in “British Journal of Dermatology” The cyst had unusual keratin spherules and resembled bone marrow.
55 citations
,
January 2004 in “The International Journal of Developmental Biology” Corneal cells can transform into hair-producing skin cells when exposed to certain signals.
86 citations
,
February 2012 in “Journal of Clinical Investigation” Stem cells in hair follicles are diverse and change throughout the hair cycle.
April 2017 in “Plastic and reconstructive surgery. Global open” Baby and adult skin cells are different, with baby cells having more active pathways that could help grow new hair follicles.
K15 and Id3 are important in hair follicle regeneration, with K15 increasing in early stages and Id3 responding later.
1 citations
,
July 2006 in “Journal of Investigative Dermatology” A 4kb fragment of the desmocollin 3 promoter targets gene expression to specific skin and hair follicle areas.
32 citations
,
February 2019 in “eLife” BMP signaling is essential for the development of touch domes.
2 citations
,
June 2013 in “In Vitro Cellular & Developmental Biology - Animal” Melanocytes from human fetal hair follicles were successfully cultured, showing potential for hair disease research and clinical use.
January 2006 in “Zhongguo bingli shengli zazhi” Murine epidermal stem cells can develop into skin structures without rejection when implanted.
January 2002 in “Basic medical sciences and clinics” Hair follicle stem cells are crucial for hair growth and renewal.
11 citations
,
January 2013 in “Veterinary dermatology” Keratinocytes from dog hair follicles can create a functional skin layer in a lab model, useful for dog skin therapy.
1 citations
,
April 2016 in “PubMed” Epidermis and dermis cells together can regenerate hair follicles.
February 2022 in “Cosmetic Dermatology” Healthy skin prevents water loss and protects against threats.
26 citations
,
July 1993 in “Journal of Investigative Dermatology” April 2013 in “Cancer Research” SKH1 hairless mice have identifiable epidermal stem cells with specific markers.
8 citations
,
June 2022 in “Scientific Reports” LGR5 is a common marker of hair follicle stem cells in different animals and is important for hair growth and regeneration.
August 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” The research found that specific stem cells maintain skin gland openings and that disrupting their activity can cause blockages or early cancer signs, indicating a need for targeted treatments.
July 2025 in “Genome biology” HT-scCAT-seq helps understand gene regulation in embryonic skin development.
February 2019 in “American International Journal of Humanities Arts and Social Sciences” The dermis of Millivora Capenesis has two layers with various connective tissues, blood vessels, glands, and sensory structures.
43 citations
,
September 2009 in “Stem Cells” A nonviral method was developed to label and culture human hair follicle stem cells.
24 citations
,
December 2013 in “Archives of Dermatological Research” 26 citations
,
December 2013 in “Seminars in cell & developmental biology” Skin varies in thickness, color, and features due to complex genetic and cellular processes.
39 citations
,
March 2022 in “Nature Protocols” Scientists created hair-growing skin models from stem cells, which could help treat hair loss and skin diseases.