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Spironolactone treatment reduced hair growth and androgen levels in hirsute women, but the overall effectiveness was just adequate.

Treatment with a hormone agonist can reduce excess male hormones in postmenopausal women without surgery.

Neurosteroid withdrawal increases α4 subunit expression in the hippocampus, which may relate to catamenial epilepsy in women.

Targeting 5α-reductase type 1 may help manage Tourette-like symptoms.

Both Diane 35 combinations effectively and safely reduce hirsutism and acne, with potential for better results if treatment extends beyond 12 months.

Finasteride 1 mg/day reduces semen quality without affecting hormones or sexual function.

Certain hormones can reduce skin oil and hair growth, potentially helping treat acne and excessive hair in women.

Trazodone and chlorpromazine may help treat sexual dysfunction caused by finasteride and SSRIs.

GnRH agonists can help manage recurrent priapism in sickle cell patients, but long-term safety is unclear.

The method is quick and effective for testing steroid 5 alpha-reductase inhibitors.

Predstanormix Duo is a safe and effective new drug for treating urinary symptoms from BPH.

Spironolactone can cause side effects like high potassium levels and breast enlargement, and patients need careful monitoring.

Spironolactone was effective in reducing hair growth in women with hirsutism.

Clascoterone is a new, effective, and safe acne treatment without systemic side effects.

Epristeride's metabolism involves key metabolites and proteins, affecting its use in doping tests.

CB-03-04 shows promise as a treatment for prostate issues due to its strong anti-androgen effects.

Flutamide is more effective and has fewer side effects than spironolactone for treating hirsutism.

Compounds 15, 20, and 25 are strong inhibitors of human steroid 5α-reductase type 2.

Clascoterone 1% cream is a promising new treatment for acne.

Certain compounds reduced hamster flank organ size by inhibiting 5α-reductase, like finasteride, without affecting androgen receptors.

5α-reductase affects dopamine receptors linked to sensorimotor gating, which may help understand disorders like schizophrenia.

Allopregnanolone and opioids together reduce stress hormone responses during pregnancy.

Cyproterone acetate is a safe treatment that causes mild feminizing effects in adolescent trans-girls.

Higher 3α,5α-THP levels in the brain may reduce depression in pregnant rats.

Bimatoprost treats glaucoma and promotes hair growth, with potential for more medical uses.

17α-estradiol lotion can reduce hair loss but doesn't promote new hair growth.

A teenage girl's excessive hair growth was caused by a medication for mania, but improved after stopping the medication.