4 citations
,
August 2018 in “Facial Plastic Surgery Clinics of North America” Platelet-Rich Plasma (PRP), a protein-rich extract from a patient's blood, shows promise in improving hair density, thickness, and quality, but the best method of use and number of treatments needed for noticeable results are still unclear.
April 2023 in “The journal of investigative dermatology/Journal of investigative dermatology” Blocking EGFR can lead to hair loss due to inflammation and stem cell damage.
7 citations
,
March 2007 in “International Journal of Dermatology” Targeting FGFR-1 with antisense oligonucleotides may help treat baldness by increasing hair follicle activity.
December 2025 in “Lviv clinical bulletin” PRP therapy may help with ovarian issues and fertility, but more research is needed.
78 citations
,
June 2003 in “Journal of Investigative Dermatology Symposium Proceedings” TGF-β1 from dermal papilla cells suppresses hair growth, and targeting it may help treat androgenetic alopecia.
9 citations
,
January 2018 in “International Journal of Trichology” A woman's hair loss from graft versus host disease helps understand similar hair loss conditions.
October 2025 in “Clinical Case Reports” PRP injection for hair growth can cause reversible vision loss due to inflammatory optic neuropathy.
11 citations
,
January 2015 in “Journal of cellular physiology” HR protein causes abnormal hair cycles by increasing Tgf-β2 and reducing miR-31.
25 citations
,
May 2013 in “Experimental Dermatology” Epidermal growth factor helps hair recover after chemotherapy.
April 2023 in “Journal of Investigative Dermatology” PRP shows promise for treating hair loss but needs more research.
Arabidopsis Formin 2 stabilizes actin filaments to aid cell-to-cell trafficking.
8 citations
,
January 2019 in “The journal of investigative dermatology/Journal of investigative dermatology” Growth hormone is important for regulating human hair growth.
13 citations
,
July 2016 in “BMC Complementary and Alternative Medicine” Hominis Placenta helps hair grow back by increasing cell growth and a specific growth factor.
252 citations
,
November 1995 in “The EMBO Journal” Blocking EGFR in mice causes hair loss and skin changes.
April 2017 in “Journal of Investigative Dermatology” Laser treatment may help with hair growth in some people with frontal fibrosing alopecia, but results vary and the exact way it works is unclear.
75 citations
,
September 2007 in “Journal of Heredity” FGF5 gene mutations cause long hair in domestic cats.
November 2022 in “bioRxiv (Cold Spring Harbor Laboratory)” Prostaglandin E2 helps prevent hair loss from radiotherapy by protecting hair cells.
March 2016 in “Experimental Dermatology” EGFR helps hair follicles transition properly by controlling Stathmin levels.
1 citations
,
February 2020 in “International journal of research in dermatology” PRP therapy is effective for hair loss, skin rejuvenation, wound healing, and scar treatment.
23 citations
,
May 2020 in “Cell Death and Disease” Blocking the FGF5 gene in sheep leads to more fine wool and active hair follicles due to changes in certain cell signaling pathways.
4 citations
,
March 2008 in “Hair transplant forum international” PRP reduces complications in hair transplants.
4 citations
,
October 2024 in “BMC Oral Health” Platelet-rich fibrin shows promise for treating oral lesions but needs more research.
August 2019 in “Journal of the American Academy of Dermatology” Frontal fibrosing alopecia may be caused by an autoimmune reaction and hormonal imbalance.
31 citations
,
March 2020 in “International Journal of Regenerative Medicine” PRP treatment can safely boost hormone levels in some IVF patients with low ovarian reserve.
April 2012 in “Cancer Research” EGFR deficiency in skin causes hair follicle issues and inflammation.
53 citations
,
August 2005 in “The Journal of Cell Biology” Sgk3 is essential for normal hair follicle growth and maintenance.
44 citations
,
January 2006 in “Biological & Pharmaceutical Bulletin” Androgen hormones cause hair follicle scarring in hair loss, and finasteride helps reduce it.
January 2026 in “OSF Preprints (OSF Preprints)” This paper introduces a comprehensive therapeutic framework for androgenetic alopecia (AGA) that combines PROTAC-mediated androgen receptor (AR) degradation with regenerative and micro-environmental strategies. It highlights GT20029 as a topical AR-PROTAC and compares AR degradation with antagonism. The study also explores early-intervention models based on genetic predisposition and pre-miniaturization biomarkers. The framework integrates stem-cell biology, dermal papilla senescence, perifollicular fibrosis, and niche-engineering into a three-phase protocol: stabilization, reversal, and maintenance. Additionally, it proposes a development timeline for therapies and testable hypotheses to guide future research and clinical applications in AGA.
June 2024 in “Saudi Journal of Medicine” PRP therapy significantly improves hair thickness and density in male pattern baldness.
PRP hair treatment is generally safe but may cause minor pain, bleeding, redness, and scalp tightness, and isn't suitable for everyone.