research Celsr1 and Celsr2 exhibit distinct adhesive interactions and contributions to planar cell polarity
Celsr1 is crucial for skin cell alignment, while Celsr2 has little effect on this process.
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research Lineage potential, plasticity and environmental reprogramming of epithelial stem/progenitor cells
Environmental cues can change the fate and function of epithelial cells, with potential for cell therapy.
research Shushing down the epigenetic landscape towards stem cell differentiation
The document concludes that pig iPSCs show promise for transplant therapies and the field is advancing in controlling cell behavior for biology and medicine.
research Cell-Type-Specific Chromatin States Differentially Prime Squamous Cell Carcinoma Tumor-Initiating Cells for Epithelial to Mesenchymal Transition
Different types of skin cells have unique genetic markers that affect how likely they are to spread cancer.
research Smurf2-induced degradation of SMAD2 causes inhibition of hair follicle stem cell differentiation
Increasing Smurf2 hinders hair follicle stem cell differentiation and wound healing.
research Pluripotent Stem Cell Technology: A Promising Remedy for Hypopigmentation Disorders
Pluripotent stem cells show promise for treating skin color loss disorders like vitiligo.
research The Role of Adipocytes in Tissue Regeneration and Stem Cell Niches
Fat cells are important for tissue repair and stem cell support in various body parts.
research Extracellular vesicles from 3D cultured dermal papilla cells improve wound healing via Krüppel-like factor 4/vascular endothelial growth factor A -driven angiogenesis
Tiny particles from 3D-grown skin cells speed up wound healing by promoting blood vessel growth.
research Activation of β-Catenin Signaling in CD133-Positive Dermal Papilla Cells Drives Postnatal Hair Growth
Activating β-catenin in certain skin cells speeds up hair growth in mice.
research New substrates for stem cell control
New materials help control stem cell growth and specialization for medical applications.
research Effective high-throughput isolation of enriched platelets and circulating pro-angiogenic cells to accelerate skin-wound healing
Angio PRP speeds up skin wound healing and reduces inflammation.
research Coordinated Activation of Wnt in Epithelial and Melanocyte Stem Cells Initiates Pigmented Hair Regeneration
Wnt signaling is crucial for pigmented hair regeneration by controlling stem cell activation and differentiation.
research Overactivated sonic hedgehog signaling aggravates intrauterine adhesion via inhibiting autophagy in endometrial stromal cells
Overactive sonic hedgehog signaling worsens uterine scarring by reducing cell recycling.
research Responses of hair follicle–associated structures to loss of planar cell polarity signaling
Loss of Fz6 disrupts hair follicle and associated structures' orientation.
research WNT10A mutation causes ectodermal dysplasia by impairing progenitor cell proliferation and KLF4-mediated differentiation
A WNT10A gene mutation leads to ectodermal dysplasia by disrupting cell growth and differentiation.
research Spatiotemporal Labeling of Melanocytes in Mice
The research showed how melanocytes develop, move, and respond to UV light, and their stem cells' role in hair color and skin cancer risk.
research Shh pathway in wounds in non-diabetic Shh-Cre-eGFP/Ptch1-LacZ mice treated with MAA beads
MAA beads improved wound healing in male mice by activating the Shh pathway, but not in females.
research Optimal stimulation toward the dermal papilla lineage can be promoted by combined use of osteogenic and adipogenic inducers
Combining specific inducers helps dermal papilla cells regain hair-forming ability.
research Decision letter: Interplay of opposing fate choices stalls oncogenic growth in murine skin epithelium
Skin cells can naturally limit the growth of cancerous changes by balancing cell renewal and differentiation.
research Faculty Opinions recommendation of Lrig1 expression defines a distinct multipotent stem cell population in mammalian epidermis.
Lrig1 marks a unique group of stem cells in mouse skin that can become different skin cell types.
research Skin tissue engineering
Improved understanding of stem cell mechanisms can enhance skin tissue engineering.
research Biology of melanocytes in mammals
Melanocytes are important for skin and hair color and protect the skin from UV damage.
research 3D spheroid culture synchronizes heterogeneous MSCs into an immunomodulatory phenotype with enhanced anti-inflammatory effects
3D spheroid culture makes stem cells better at reducing inflammation.
research Large-Scale Preparation of Hair Follicle Germs Using a Microfluidic Device
A new method using a microfluidic device can prepare hair follicle germs efficiently for potential use in hair loss treatments.
research Subcutaneous injection of genetically engineered exosomes for androgenic alopecia treatment
EX104 shows promise in treating hair loss by promoting hair growth and improving scalp health.
research Follicle-innervating Aδ-low threshold mechanoreceptors organize through a population-dependent mechanism
Mouse touch-sensitive nerve cells adjust their connections based on competition with other similar cells.
research Author response: Generation of inner ear hair cells by direct lineage conversion of primary somatic cells
Four transcription factors can convert mouse cells into hair cell-like cells, aiding hearing loss research and treatment.
research Morphogenesis of chimeric hair follicles in engineered skin substitutes with human keratinocytes and murine dermal papilla cells
Engineered skin can grow chimeric hair follicles only with mouse dermal papilla cells.
research Progenitor-derived endothelin controls dermal sheath contraction for hair follicle regression
A specific signal from hair cells controls the tightening of the surrounding muscle, which is necessary for hair shedding.
research A Window into Mammalian Basement Membrane Development: Insights from themTurq2-Col4a1Mouse Model
The mTurq2-Col4a1 mouse model shows that cells can divide while attached to stable basement membranes during development.