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research Safety and efficacy of advanced and targeted acid α-glucosidase (AT-GAA) (ATB200/AT2221) in ERT-switch nonambulatory patients with Pompe disease: preliminary results from the ATB200-02 trial

3 citations , February 2019 in “Molecular genetics and metabolism”

The combination of tadalafil and finasteride improves urinary symptoms and erectile function in men with enlarged prostates.

research Efficacy and safety of topical GT20029 in male patients with androgenetic alopecia: a multicenter, randomized, double-blind, placebo-controlled phase 2 study

January 2025

Topical GT20029 effectively promotes hair regrowth and is well-tolerated.

Cystatin M/E Is a High Affinity Inhibitor of Cathepsin V and Cathepsin L by a Reactive Site Distinct from the Legumain-binding Site

research Cystatin M/E Is a High Affinity Inhibitor of Cathepsin V and Cathepsin L by a Reactive Site That Is Distinct from the Legumain-binding Site

100 citations , March 2006 in “Journal of biological chemistry/The Journal of biological chemistry”

Cystatin M/E strongly inhibits cathepsin V and cathepsin L, important for skin formation.

The VEGF +405 G>C 5' Untranslated Region Polymorphism and Risk of PCOS: A Study in South Indian Women

research The VEGF +405 G>C 5' untranslated region polymorphism and risk of PCOS: a study in the South Indian Women

28 citations , August 2014 in “Journal of Assisted Reproduction and Genetics”

The VEGF +405G allele may increase the risk of PCOS in South Indian women.

research Serine-rich ultra high sulfur protein gene expression in murine hair and skin during the hair cycle

1 citations , February 1991 in “Journal of Biological Chemistry”

research Defining a Region of the Human Keratin 6a Gene That Confers Inducible Expression in Stratified Epithelia of Transgenic Mice

44 citations , May 1997 in “Journal of Biological Chemistry”

The human keratin 6a gene's specific sequences trigger expression in skin layers after injury.

research Identification and characterization of the hamster polyomavirus middle T antigen

52 citations , June 1991 in “Journal of Virology”

The hamster polyomavirus middle T antigen is linked to tumors in hamsters and associates with a specific tyrosine kinase.

research Conditional expression of the ErbB2 oncogene elicits reversible hyperplasia in stratified epithelia and up-regulation of TGFα expression in transgenic mice

150 citations , June 1999 in “Oncogene”

Expression and Distribution of the Guanine Nucleotide-Binding Protein Subunit Alpha-S in Mice Skin Tissues and Its Association with White and Black Coat Colors

research Expression and Distribution of the Guanine Nucleotide-binding Protein Subunit Alpha-s in Mice Skin Tissues and Its Association with White and Black Coat Colors

1 citations , January 2016 in “Asian-Australasian journal of animal sciences”

The protein GnÎ±s is found more in black mice than white mice and may influence their coat color.

research 034 Characterization of novel TMEM173 mutation causing a lupus- and SAVI-like phenotype, modified by polymorphisms in TMEM173 and IFIH1

September 2019 in “The journal of investigative dermatology/Journal of investigative dermatology”

A new mutation in the STING protein causes a disease with lupus-like symptoms and responds well to a specific inhibitor treatment.

research Decreased GATA3 levels cause changed mouse cutaneous innate lymphoid cell fate, facilitating hair follicle recycling

5 citations , May 2024 in “Developmental Cell”

Lower GATA3 levels in mice help hair regrow by changing certain immune cells.

research The role of Atg5i> gene in tumorigenesis under autophagy deficiency conditions

4 citations , June 2024 in “The Kaohsiung Journal of Medical Sciences”

Atg5 can promote tumors when autophagy is deficient but suppresses them under normal conditions.

research Tβ4-overexpression based on the piggyBac transposon system in cashmere goats alters hair fiber characteristics
18 citations , November 2016 in “Transgenic research”

Overexpressing Tβ4 in cashmere goats improves hair fiber traits and increases cashmere yield.

research Topical Gene Electrotransfer to the Epidermis of Hairless Guinea Pig by Non-Invasive Multielectrode Array
22 citations , August 2013 in “PLOS ONE”

The method safely and efficiently delivers genes to the skin but may not work for conditions needing high levels of gene products.

research Uso de la simulación en el control de errores en la Rasterización
2 citations , January 1997 in “Mapping”

Gambogic Amide may prevent hair greying and promote hair growth by maintaining hair pigmentation.

research iε-(γ^-Glutamyl) lysine cross-linkage in citrulline-containing protein fractions from hair
125 citations , February 1971 in “Biochemistry”

Specific cross-linkages help make hair proteins stable and strong.

research DataSheet1.zip
December 2021

GPC1 is important for hair growth by helping blood vessels form around hair follicles.

research Identification of dual-purpose therapeutic targets implicated in aging and glioblastoma multiforme using PandaOmics - an AI-enabled biological target discovery platform
17 citations , April 2023 in “Aging”

CNGA3, GLUD1, and SIRT1 are promising targets for treating aging and glioblastoma.

research Helminth protein enhances wound healing by inhibiting fibrosis and promoting tissue regeneration
August 2024 in “Life Science Alliance”

Helminth protein helps wounds heal better by reducing scarring and promoting tissue growth.

research Independent DSG4 frameshift variants in cats with hair shaft dystrophy
December 2021 in “Molecular genetics and genomics”

Cats with abnormal hair had DSG4 gene changes causing hair problems.

research Mutations in the Serum/Glucocorticoid Regulated Kinase 3 (Sgk3) Are Responsible for the Mouse Fuzzy (fz) Hair Phenotype
11 citations , October 2007 in “Journal of Investigative Dermatology”

Mutations in the Sgk3 gene cause fuzzy hair in mice.

research Correction of Hair Shaft Defects through Allele-Specific Silencing of Mutant Krt75
6 citations , September 2015 in “Journal of Investigative Dermatology”

Using special RNA to target a mutant gene fixed hair problems in mice.

research Enzyme Replacement Therapy Ameliorates Multiple Symptoms of Murine Homocystinuria
29 citations , December 2017 in “Molecular therapy”

Enzyme replacement therapy improved multiple symptoms of homocystinuria in mice.

research Deletion of an Enhancer in FGF5 is Associated With Ectopic Expression in Goat Hair Follicles and the Cashmere Growth Phenotype
1 citations , October 2020 in “Research Square (Research Square)”

A genetic variant in goats is linked to cashmere growth.

research Novel D323G mutation of DSG4i> gene in a girl with localized autosomal recessive hypotrichosis clinically overlapped with monilethrix
8 citations , July 2015 in “International Journal of Dermatology”

A new DSG4 gene mutation causes hair defects in a young girl.

research Overexpression of cotton Trihelix transcription factor GhGT-3b_A04 enhances resistance to Verticillium dahliae and affects plant growth in Arabidopsis thaliana
February 2023 in “Journal of Plant Physiology”

research The Region Coding for the Helix Termination Motif and the Adjacent Intron 6 of the Human Type I Hair Keratin Gene hHa2 Contains Three Natural, Closely Spaced Polymorphic Sites
6 citations , March 1996 in “Journal of Investigative Dermatology”

research NUDT15i>,FTOi>, andRUNX1i>genetic variants and thiopurine intolerance among Japanese patients with inflammatory bowel diseases
40 citations , January 2017 in “Intestinal Research”

Genotyping for NUDT15 p.Arg139Cys can help predict thiopurine side effects in Japanese IBD patients.

research A homozygous missense mutation in the fibroblast growth factor 5 gene is associated with the long-hair trait in Angora rabbits
5 citations , June 2023 in “BMC genomics”

A specific gene mutation causes long hair in Angora rabbits.

research Activation of the transcription factor Gli1 and the Sonic hedgehog signalling pathway in skin tumours
638 citations , October 1997 in “Nature”

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Research

research Safety and efficacy of advanced and targeted acid α-glucosidase (AT-GAA) (ATB200/AT2221) in ERT-switch nonambulatory patients with Pompe disease: preliminary results from the ATB200-02 trial

research Efficacy and safety of topical GT20029 in male patients with androgenetic alopecia: a multicenter, randomized, double-blind, placebo-controlled phase 2 study

research Cystatin M/E Is a High Affinity Inhibitor of Cathepsin V and Cathepsin L by a Reactive Site That Is Distinct from the Legumain-binding Site

research The VEGF +405 G>C 5' untranslated region polymorphism and risk of PCOS: a study in the South Indian Women

research Serine-rich ultra high sulfur protein gene expression in murine hair and skin during the hair cycle

research Defining a Region of the Human Keratin 6a Gene That Confers Inducible Expression in Stratified Epithelia of Transgenic Mice

research Identification and characterization of the hamster polyomavirus middle T antigen

research Conditional expression of the ErbB2 oncogene elicits reversible hyperplasia in stratified epithelia and up-regulation of TGFα expression in transgenic mice

research Expression and Distribution of the Guanine Nucleotide-binding Protein Subunit Alpha-s in Mice Skin Tissues and Its Association with White and Black Coat Colors

research 034 Characterization of novel TMEM173 mutation causing a lupus- and SAVI-like phenotype, modified by polymorphisms in TMEM173 and IFIH1

research Decreased GATA3 levels cause changed mouse cutaneous innate lymphoid cell fate, facilitating hair follicle recycling

research The role of Atg5i> gene in tumorigenesis under autophagy deficiency conditions

research Tβ4-overexpression based on the piggyBac transposon system in cashmere goats alters hair fiber characteristics

research Topical Gene Electrotransfer to the Epidermis of Hairless Guinea Pig by Non-Invasive Multielectrode Array

research Uso de la simulación en el control de errores en la Rasterización

research iε-(γ^-Glutamyl) lysine cross-linkage in citrulline-containing protein fractions from hair

research DataSheet1.zip

research Identification of dual-purpose therapeutic targets implicated in aging and glioblastoma multiforme using PandaOmics - an AI-enabled biological target discovery platform

research Helminth protein enhances wound healing by inhibiting fibrosis and promoting tissue regeneration

research Independent DSG4 frameshift variants in cats with hair shaft dystrophy

research Mutations in the Serum/Glucocorticoid Regulated Kinase 3 (Sgk3) Are Responsible for the Mouse Fuzzy (fz) Hair Phenotype

research Correction of Hair Shaft Defects through Allele-Specific Silencing of Mutant Krt75

research Enzyme Replacement Therapy Ameliorates Multiple Symptoms of Murine Homocystinuria

research Deletion of an Enhancer in FGF5 is Associated With Ectopic Expression in Goat Hair Follicles and the Cashmere Growth Phenotype

research Novel D323G mutation of DSG4i> gene in a girl with localized autosomal recessive hypotrichosis clinically overlapped with monilethrix

research Overexpression of cotton Trihelix transcription factor GhGT-3b_A04 enhances resistance to Verticillium dahliae and affects plant growth in Arabidopsis thaliana

research The Region Coding for the Helix Termination Motif and the Adjacent Intron 6 of the Human Type I Hair Keratin Gene hHa2 Contains Three Natural, Closely Spaced Polymorphic Sites

research NUDT15i>,FTOi>, andRUNX1i>genetic variants and thiopurine intolerance among Japanese patients with inflammatory bowel diseases

research A homozygous missense mutation in the fibroblast growth factor 5 gene is associated with the long-hair trait in Angora rabbits

research Activation of the transcription factor Gli1 and the Sonic hedgehog signalling pathway in skin tumours