Search

for
Search:

Sort by

Research

570-600 / 1000+ results

research Overexpression of protein kinase C-α in the epidermis of transgenic mice results in striking alterations in phorbol ester-induced inflammation and COX-2, MIP-2 and TNF-α expression but not tumor promotion

135 citations , October 1999 in “Journal of Cell Science”

Overexpressing PKCα in mice skin increases inflammation but doesn't affect tumor growth.

Large-Scale Skin scRNA-Seq Profiling Highlights Distinct Body Site-Specific Ligand-Receptor Interactions and Pathways in Keratinocytes

research LB1671 Large-scale skin scRNA-seq profiling highlights distinct body site-specific ligand-receptor interactions and pathways in keratinocytes

August 2023 in “Journal of Investigative Dermatology”

Different body areas have unique skin cell communication patterns, explaining why certain skin diseases occur in specific regions.

research The role of ghrelin and ghrelin receptors in polycystic ovary syndrome

July 2005 in “TSpace (University of Toronto)”

Ghrelin and its receptors likely aren't risk factors for PCOS.

research Mrp3, a Mitogen-Regulated Protein/Proliferin Gene Expressed in Wound Healing and in Hair Follicles

19 citations , May 2001 in “Endocrinology”

Mrp3 may aid in wound healing and hair growth.

research Genetic targeting of lymphatic endothelial cells in mice: current strategies and future perspectives

5 citations , January 2024 in “The International Journal of Developmental Biology”

Mouse models help target specific genes in lymphatic cells for research.

Oncogenic Kras Induces Spatiotemporally Specific Tissue Deformation Through Converting Pulsatile Into Sustained ERK Activation

research Oncogenic Kras induces spatiotemporally specific tissue deformation through converting pulsatile into sustained ERK activation

September 2022 in “bioRxiv (Cold Spring Harbor Laboratory)”

The Kras mutation changes normal cell signals, leading to disrupted tissue structure and potential cancer.

Knock-Down of Arabidopsis PLC5 Reduces Primary Root Growth and Secondary Root Formation While Overexpression Improves Drought Tolerance and Causes Stunted Root Hair Growth

research Knock-Down of Arabidopsis PLC5 Reduces Primary Root Growth and Secondary Root Formation While Overexpression Improves Drought Tolerance and Causes Stunted Root Hair Growth

38 citations , June 2018 in “Plant & cell physiology/Plant and cell physiology”

Changing the amount of PLC5 in Arabidopsis affects root growth and drought resistance, with less PLC5 slowing root growth and more PLC5 improving drought tolerance but hindering root hair growth.

research Trans glutaminase-mediated cross-linking in mammalian epidermis

44 citations , January 1984 in “Molecular and Cellular Biochemistry”

research Mechanism of action of NLRP3 protein macromolecule based on electrochemical sensors in the treatment of alopecia areata in mice: The role of Ritlecitinib in AA mice through NLRP3

March 2026 in “Microchemical Journal”

research Hutchinson-Gilford Progeria Syndrome: Premature Aging

April 2026

RNA-based treatments show promise for managing Hutchinson-Gilford Progeria Syndrome.

research Desmoglein 4 Mutations Underlie Localized Autosomal Recessive Hypotrichosis in Humans, Mice, and Rats

13 citations , August 2005 in “Journal of Investigative Dermatology Symposium Proceedings”

Mutations in the DSG4 gene cause fragile, sparse hair in humans, mice, and rats.

research Thymic stromal lymphopoietin controls hair growth

5 citations , February 2022 in “Stem cell reports”

Thymic stromal lymphopoietin (TSLP) promotes hair growth, especially after skin injury.

research Dual role of laminin‑511 in regulating melanocyte migration and differentiation

17 citations , September 2018 in “Matrix Biology”

Laminin-511 is essential for proper melanocyte movement and development in mice.

research Il-10 family members as novel responders to genotoxic stress

January 2015 in “ScholarlyCommons (University of Pennsylvania)”

IL-19 and IL-24 help cells respond to DNA damage and could be targeted for cancer and age-related disease treatments.

research Krt6a-Cre Transgenic Mice Direct LoxP-Mediated Recombination to the Companion Cell Layer of the Hair Follicle and Following Induction by Retinoic Acid to the Interfollicular Epidermis

10 citations , January 2004 in “Journal of Investigative Dermatology”

Krt6a-Cre transgenic mice help study gene effects on hair follicle development and tumor suppression.

research PROTACs in cancer therapy: targeted degradation of GPX4, PARP and epigenetic regulators

March 2026 in “Journal of Enzyme Inhibition and Medicinal Chemistry”

PROTACs show promise in cancer treatment by effectively degrading specific harmful proteins.

research Spermidine/spermine-N¹-acetyltransferase: a key metabolic regulator

305 citations , March 2008 in “AJP Endocrinology and Metabolism”

SSAT is a key enzyme affecting cell growth and metabolism, with potential but risky use in disease treatment.

research Chaperones as thermodynamic sensors

August 2013 in “Nature Reviews Drug Discovery”

New cancer treatments show promise in reducing tumor growth and improving skin regeneration in mice.

research LB1048 Effectiveness of OR-101 in a murine model of atopic dermatitis

July 2024 in “Journal of Investigative Dermatology”

OR101 may effectively treat atopic dermatitis and similar skin conditions.

research Skin-specific expression of a truncated E1a oncoprotein binding to p105-Rb leads to abnormal hair follicle maturation without increased epidermal proliferation.

30 citations , June 1993 in “The Journal of Cell Biology”

The oncoprotein causes abnormal hair growth without increasing skin cancer risk.

research A new mutation Rim3 resembling Re den is mapped close to retinoic acid receptor alpha (Rara) gene on mouse Chromosome 11

76 citations , January 1998 in “Mammalian Genome”

research Correction of ornithine transcarbamylase (OTC) deficiency in spf‐ash mice by introduction of rat OTC gene

14 citations , February 1991 in “FEBS Letters”

Introducing the rat OTC gene partially corrected OTC deficiency in mice.

research Glutamic acid promotes hair growth in mice

12 citations , July 2021 in “Scientific Reports”

Glutamic acid helps increase hair growth in mice.

research Overexpression of Lnk in the Ovaries Is Involved in Insulin Resistance in Women With Polycystic Ovary Syndrome

11 citations , July 2016 in “Endocrinology”

Higher Lnk protein levels in ovaries may lead to insulin resistance in women with PCOS.

research The promoter of an androgen dependent gene in the hamster flank organ

6 citations , May 1997 in “Journal of Dermatological Science”

Researchers found a gene in hamsters that responds to male hormones and may be indirectly controlled by them.

ELife Assessment: Touch Receptor End-Organ Innervation and Function Require Sensory Neuron Expression of the Transcription Factor Meis2

research eLife assessment: Touch receptor end-organ innervation and function require sensory neuron expression of the transcription factor Meis2

February 2024

Meis2 is essential for touch sensation and proper nerve connection to touch receptors in certain skin areas of mice.

GRHL3 Binding and Enhancers Rearrange as Epidermal Keratinocytes Transition Between Functional States

← Previous page Next page →