The document concludes that Syndromes of Severe Insulin Resistance are rare disorders with limited treatment options.
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January 2016 in “Recent Advances in Biology and Medicine” Smeathxanthone A improves wound healing and lowers blood sugar in diabetic mice.
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June 2020 in “Journal of Advanced Research” High-dose vitamin A and E with zinc improved blood sugar control and insulin function in diabetics, but may cause hair loss.
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June 2018 in “Life Sciences” Diabetex improves diabetic wound healing better than metformin.
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January 2018 in “Dermato-endocrinology” Darkened knuckles can be an early sign of insulin resistance.
February 2026 in “Endokrynologia Polska” Early diagnosis and treatment are crucial for managing Berardinelli–Seip syndrome.
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January 2012 in “Internal Medicine” A Rathke's cleft cyst caused hormonal imbalances and symptoms in a 68-year-old woman.
Glycosylated keratin levels in hair can help identify the onset of insulin-dependent diabetes.
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May 2011 in “Bioorganic & Medicinal Chemistry” Changing the 6-position on benzopyran molecules affects insulin release, with some compounds showing strong inhibitory effects.
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April 1998 in “Journal of Investigative Dermatology” ACTH promotes hair growth in mink, but α-MSH does not.
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January 2026 in “International Journal of Health Science” Human insulin via microinfusion may effectively improve atrophic acne scars.
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February 1989 in “PubMed” Hair glycation can indicate long-term blood sugar levels and diabetic nerve issues.
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March 2015 in “PLOS ONE” Fibroblast Growth Factor-9 (FGF-9) can help improve heart function in diabetic mice after a heart attack by reducing inflammation and harmful changes to the heart's structure.
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January 2008 in “Cochrane Database of Systematic Reviews” Glucocorticoid corticosteroids improve muscle strength in Duchenne muscular dystrophy but can cause side effects.
September 2023 in “Tạp chí Y Dược học Cần Thơ” Shallot extract effectively lowers blood sugar levels.
June 2025 in “Mağallaẗ ʻulūm al-rāfidayn” Combining metformin with amoxicillin/clavulanate lowers blood sugar in diabetic female rats.
October 2004 in “Australian Prescriber” Agalsidase alfa helps treat Fabry's disease but needs more research for long-term benefits.
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July 2019 in “Experimental Dermatology” 2-deoxy D-glucose does not help with hair regrowth in alopecia areata.
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December 2025 in “Biomaterials Research” The hydrogel effectively improves diabetic wound healing by reducing inflammation and promoting tissue repair.
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January 2020 in “European Journal of Endocrinology” Test thyroid function in all obese patients and prioritize weight loss for hormonal balance.
January 2015 in “Durham e-Theses (Durham University)” Adipose tissue changes in obesity can trigger stress in fat cells.
May 2021 in “Journal of the Endocrine Society” A patient produced cortisol after adrenalectomy, possibly due to residual tissue or other body parts making steroids.
November 2016 in “Tesis Doctorals en Xarxa (Consorci de Serveis Universitaris de Catalunya)” The VMH AMPK-SNS-BAT axis may help treat cachexia and obesity.