research Azelaic Acid in the Treatment of Acne in Adult Females: Case Reports
Azelaic Acid is effective and safe for treating adult female acne, with few side effects.
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research ROS-scavenging microneedles loaded with Portulaca oleracea L.-derived exosomes for atopic dermatitis therapy
A new microneedle patch effectively treats atopic dermatitis by reducing skin stress and restoring immune balance.
research TCM “medicine and food homology” in the management of post-COVID disorders
Traditional Chinese medicinal foods may help manage long-term post-COVID symptoms.
research Efficacy and safety evaluations of topical proretinal nanoparticles
Proretinal nanoparticles are a safe and effective way to deliver retinal to the skin.
research TGF‐β2 is specifically expressed in human dermal papilla cells and modulates hair folliculogenesis
TGF-β2 plays a key role in human hair growth and development.
research Effect of Miscanthus sinensis var. purpurascens Flower Extract on Proliferation and Molecular Regulation in Human Dermal Papilla Cells and Stressed C57BL/6 Mice
Miscanthus sinensis flower extract may help promote hair growth and prevent hair loss.
research Developing formulations designed to deliver antiseptic agents to target sites within the skin
Nanoemulsions can effectively deliver antiseptic agents deep into the skin.
research Xenobiotica-metabolizing enzymes in the skin of rat, mouse, pig, guinea pig, man, and in human skin models
Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.
research Advances in Chitosan-Based Nanoparticles for Drug Delivery
Chitosan, a natural substance, can be used to create tiny particles that effectively deliver various types of drugs, but more work is needed to improve stability and control of drug release.
research The human skin as a hormone target and an endocrine gland
Human skin acts like a hormone-producing organ, making and managing various hormones important for skin and hair health.
research Therapeutic Potential of Brassinosteroids in Biomedical and Clinical Research
Brassinosteroids may be useful in treating cancer, infections, and other diseases.
research Novel Synthetic Steroid Derivatives: Target Prediction and Biological Evaluation of Antiandrogenic Activity
New steroid compounds may help with hormonal therapy and have potential benefits for glucose disorders, but more research is needed.
research Trapa bispinosa Roxb. Pericarp Extract Exerts 5α-Reductase Inhibitory Activity in Castrated Benign Prostatic Hyperplasia Model Mice
Trapa bispinosa Roxb. extract may help reduce prostate size and cell growth in BPH.
research Efficacy of Longdan Xiegan Decoction on the Treatment of Eczema: A Systematic Review and Meta-Analysis
Longdan Xiegan decoction is more effective than conventional medicine for treating eczema.
research Functional characterization and unraveling the structural determinants of novel steroid hydroxylase CYP154C7 from Streptomyces sp. PAMC26508
CYP154C7 enzyme can effectively modify steroids and is promising for commercial use.
research Recombinant Human Annexin A5 Ameliorates Localized Scleroderma by Inhibiting the Activation of Fibroblasts and Macrophages
Recombinant Human Annexin A5 may help treat localized scleroderma by reducing skin thickening and inflammation.
research Hair Follicle Pigmentation
Hair color is determined by melanin produced and transferred in hair follicles.
research Hyperactivation of sympathetic nerves drives depletion of melanocyte stem cells
Stress can cause hair to turn gray by depleting stem cells.
research Impaired wound healing in transgenic mice overexpressing the activin antagonist follistatin in the epidermis
Overexpressing follistatin in mice delays wound healing and reduces scar size.
research Intracrine androgen biosynthesis, metabolism and action revisited
The document concludes that blocking the internal pathways that create androgens might help treat cancers that depend on sex hormones.
research Thou shall not heal: Overcoming the non-healing behaviour of diabetic foot ulcers by engineering the inflammatory microenvironment
Controlling inflammation can help heal diabetic foot ulcers.
research Insights into the angiogenic effects of nanomaterials: mechanisms involved and potential applications
Nanomaterials can aid tissue repair and healing but need more safety research.
research Exploring the new horizons of drug repurposing: A vital tool for turning hard work into smart work
research Effects of Curcumin and Its Different Formulations in Preclinical and Clinical Studies of Peripheral Neuropathic and Postoperative Pain: A Comprehensive Review
Curcumin shows promise in reducing pain and inflammation, but more research is needed.
research Evidence for 1,25-Dihydroxyvitamin D3-independent Transactivation by the Vitamin D Receptor
The vitamin D receptor can work without its usual activating molecule.
research The Immunological Impact of IL-1 Family Cytokines on the Epidermal Barrier
IL-1 family cytokines are crucial for skin defense and healing, but their imbalance can cause skin diseases.
research The Future of Alopecia Treatment: Plant Extracts, Nanocarriers, and 3D Bioprinting in Focus
New treatments like plant extracts, nanocarriers, and 3D bioprinting show promise for hair loss, but more research is needed.
research Bioconversion, Pharmacokinetics, and Therapeutic Mechanisms of Ginsenoside Compound K and Its Analogues for Treating Metabolic Diseases
Ginsenoside compound K shows promise for treating metabolic diseases like diabetes and obesity.
research Phytochemicals With Anti 5-alpha-reductase Activity: A Prospective For Prostate Cancer Treatment
Plant-based compounds might be a promising alternative for prostate cancer treatment with fewer side effects.
research Hesperidin from Orange Peel as a Promising Skincare Bioactive: An Overview
Hesperidin from orange peels is a promising natural ingredient for skincare due to its multiple beneficial properties.