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A new mutation in the human glucocorticoid receptor reduces its function and causes resistance to glucocorticoids.

Large doses of glucocorticoids are not suitable for general use in treating severe alopecia areata due to inconsistent results and risks.

Steroids stop hair growth temporarily but don't block the signals that start it.

Hormonal changes in skin may cause stretch marks.

New findings explain how genetic changes, body clocks, and certain molecules affect tissue response to stress hormones.

Targeting glucocorticoid action might help treat type-2 diabetes, but human trials are needed.

Manipulating 5α-reductase type 2 can affect liver fat production and glucocorticoid effects.

The conclusion is that genetic changes in the glucocorticoid receptor can lead to conditions affecting stress response, immunity, and metabolism, requiring personalized treatment.

Glucocorticoid use in dogs quickly causes liver changes and Cushing's syndrome symptoms.

Overexpression of the glucocorticoid receptor in mice causes developmental defects similar to ectodermal dysplasia.

Natural 5α-reduced glucocorticoids might be anti-inflammatory with fewer side effects than current options.

Thioredoxin reductase 1 does not affect glucocorticoid receptor activity in hair follicle cells.

Certain defective glucocorticoid receptor mutants move faster inside cell nuclei and work less effectively.

Researchers created a mouse model for Cushing's syndrome to study glucocorticoid excess and potential treatments.

Dexamethasone may cause hair loss by stopping cell growth.

Hair follicle bulge cells don't help skin regrow after glucocorticoid damage; interfollicular epidermis cells do.

The N363S gene variant does not cause higher adrenal androgen levels in women with polycystic ovary syndrome.

High glucocorticoids cause pancreatic malfunction and malabsorption, reversible with enzyme supplements.

Demodicosis should be considered in cats with facial skin issues exposed to inhalant glucocorticoids.

Glucocorticoid receptors help regulate genes important for skin health and hair growth.

Glucocorticoid treatment improved symptoms in a girl with Satoyoshi disease.

Higher doses of glucocorticoids increase the risk of blood clots in asthma patients.

Local skin glucocorticoid production is crucial for healthy skin, and its disruption can lead to skin diseases.

AKR1D1 controls glucocorticoid levels and receptor activity in liver cells.

People with Parkinson's disease have higher levels of cortisone in their hair, which may indicate chronic stress hormone dysfunction.

Genetic defects in the glucocorticoid receptor gene can cause conditions with abnormal sensitivity to stress hormones, and other factors may also affect this sensitivity.

Mutations in the NR3C1 gene cause a rare condition that affects hormone signaling and can lead to various symptoms, with dexamethasone as a treatment option.

Megestrol acetate helps fat-derived stem cells grow, move, and turn into fat cells through a specific receptor.

Male C57BL/6 mice show age-related fluctuations in certain hormones and their ratios in both blood and hair.

Blocking the mineralocorticoid receptor improves wound healing by reducing inflammation and promoting blood vessel growth.