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Damaging mutations in NFKB2 cause a severe and distinct form of primary immunodeficiency with early-onset and often ACTH-deficiency.

Cholesterol affects coronavirus spread and could be a target for treatment.

New treatments for COVID-19 show promise, but more effective antiviral drugs are needed.

Alopecia areata is caused by immune attacks on hair follicles, affecting hair growth and quality of life.

Insulin resistance might not be enough to worsen blood vessel function in young, nonobese women with polycystic ovary syndrome.

Microneedles are promising for disease monitoring and drug delivery due to their minimal invasiveness and versatility.

Biomaterials can help reduce skin scarring and improve wound healing.

Minoxidil and finasteride are the best for non-scarring hair loss; more research is needed for scarring hair loss treatments.

Microneedles improve delivery of plant-based compounds through the skin, aiding treatments for hair loss, cancer, and wounds.

Significant progress was made in understanding androgen excess disorders, but much is still unknown.

Nitric Oxide has potential in medicine, especially for infections and heart treatments, but its short life and delivery challenges limit its use.

Some small molecule antivirals show promise against COVID-19, but more research is needed to understand and improve them.

Steroid 5α-reductase evolved from protists and diversified in eukaryotes, with specific roles in mammals and plants.

Olive mill wastewater can be used as a sustainable source of skin-benefiting ingredients.

Vitamin D3 deficiency can worsen psoriasis by promoting Candida overgrowth.

Understanding how acne develops in different diseases could lead to new treatments.

Enzymes are classified into six types and are essential for many biological processes, with only a few targeted by drugs.

Advanced technologies can improve understanding and monitoring of skin-brain interactions.

NLRP3 helps control inflammation and repair in wound healing, making it a potential target for treatment.

Functionalized bacterial cellulose can improve medical tissue engineering.

LncRNAs play a crucial role in muscle regulation and could help develop treatments for Duchenne muscular dystrophy.

Calorie restriction changes the elemental and isotopic makeup of mouse hair and bone.

Long COVID causes a wide range of long-lasting symptoms that change over time and are hard to diagnose and treat.

Smart biomaterials and dressings show promise in treating chronic skin diseases by improving drug delivery and minimizing side effects.

Extracellular vesicles show promise for treating psoriasis by reducing inflammation and skin lesions.

CRISPR/Cas9 has improved precision and control but still faces clinical challenges.

Thyroid disease can cause skin, hair, and nail problems, and treating the thyroid condition often improves these symptoms.

Stem cell therapy shows promise for better burn healing but needs more research and standardization.

Elephants use their skin, ears, and behavior to cool down, but climate change makes it harder for them.

Hair follicles could be used to noninvasively monitor our body's internal clock and help identify risks for related diseases.